量变中的阶段性部分质变表现了___

量变中的局部性部分质变是___

揭示事物发展的趋势和道路的规律是___

“肯定和否定相互渗透，在一定意义上，肯定就是否定。”这是一种___

事物的否定方面是指___

作为辩证的否定的“扬弃”是___

辩证的否定是事物发展的环节,因为辩证的否定___

否定之否定规律___

事物发展的周期性体现了___

直线论的错误在于只看到___

循环论的错误在于___

对立统一规律揭示了___

唯物辩证法的实质和核心是___

辩证法所说的矛盾是指___

矛盾的基本属性是___

依据是___

矛盾问题的精髓是___

题的方法都是___

“任何个别（无论怎样）都是一般”。这句话的正确含义是___

在唯物辩证法看来，水果同苹果、梨、香蕉、桔子等的关系是___

“是就是是，不是就是不是，除此之外都是鬼话。”这是一种___

真象和假象的区别在于___

有的哲学家说，在大风扬起的尘土中，每一粒尘土的运动状况都是纯粹必然的。这是种___

“或然率”是指___

Economically speaking, are we better off than we were ten years ago? Twenty years ago? In their thirst for evidence on this issue, commentators seized on the recent report by the Census Bureau, which found that average household income rose by 5.2% in 2015. Unfortunately, that conclusion puts too much weight on a useful, but flawed and incomplete, statistic. Among the more significant problems with the Census’s measure are that: 1) it excludes taxes, transfers, and compensation like employer-provided health insurance; and 2) it is based on surveys rather than data. Even if precisely measured, income data exclude important determinants of economic well-being, such as the hours of work needed to earn that income. While thinking about the question, we came across a recently published article by Charles Jones and Peter Klenow, which proposes an interesting new measure of economic welfare. While by no means perfect, it is considerably more comprehensive than average income, taking into account not only growth in consumption per person but also changes in working time, life expectancy, and inequality. Moreover, it can be used to assess economic performance both across countries and over time. The Jones-Klenow method can be illustrated by a cross-country example. Suppose we want to compare the economic welfare of citizens of the U.S. and France in 2005. In 2005, as the authors observe, real consumption per person in France was only 60% as high as the U.S., making it appear that Americans were economically much better off than the French on average. However, that comparison omits other relevant factors: leisure time, life expectancy, and economic inequality. The French take longer vacations and retire earlier, so typically work fewer hours; they enjoy a higher life expectancy, presumably reflecting advantages with respect to health care, diet, lifestyle, and the like; and income and consumption are somewhat more equally distributed there than in the U.S. Because of these differences, comparing France’s consumption with the U.S.’s overstates the gap in economic welfare. Similar calculations can be used to compare the U.S. and other countries. For example, this calculation puts economic welfare in the United Kingdom at 97% of U.S. levels, but estimates Mexican well-being at 22%. The Jones-Klenow measure can also assess an economy’s performance over time. According to this measure, as of the early-to-mid-2000s, the U.S. had the highest economic welfare of any large country. Since 2007, economic welfare in the U.S. has continued to improve. However, the pace of improvement has slowed markedly. Methodologically, the lesson from the Jones-Klenow research is that economic welfare is multi-dimensional. Their approach is flexible enough that in principle other important quality-of-life changes could be incorporated—for example, decreases in total emissions of pollutants and declines in crime rates. What does the author think of the 2015 report by the Census Bureau?___

Economically speaking, are we better off than we were ten years ago? Twenty years ago? In their thirst for evidence on this issue, commentators seized on the recent report by the Census Bureau, which found that average household income rose by 5.2% in 2015. Unfortunately, that conclusion puts too much weight on a useful, but flawed and incomplete, statistic. Among the more significant problems with the Census’s measure are that: 1) it excludes taxes, transfers, and compensation like employer-provided health insurance; and 2) it is based on surveys rather than data. Even if precisely measured, income data exclude important determinants of economic well-being, such as the hours of work needed to earn that income. While thinking about the question, we came across a recently published article by Charles Jones and Peter Klenow, which proposes an interesting new measure of economic welfare. While by no means perfect, it is considerably more comprehensive than average income, taking into account not only growth in consumption per person but also changes in working time, life expectancy, and inequality. Moreover, it can be used to assess economic performance both across countries and over time. The Jones-Klenow method can be illustrated by a cross-country example. Suppose we want to compare the economic welfare of citizens of the U.S. and France in 2005. In 2005, as the authors observe, real consumption per person in France was only 60% as high as the U.S., making it appear that Americans were economically much better off than the French on average. However, that comparison omits other relevant factors: leisure time, life expectancy, and economic inequality. The French take longer vacations and retire earlier, so typically work fewer hours; they enjoy a higher life expectancy, presumably reflecting advantages with respect to health care, diet, lifestyle, and the like; and income and consumption are somewhat more equally distributed there than in the U.S. Because of these differences, comparing France’s consumption with the U.S.’s overstates the gap in economic welfare. Similar calculations can be used to compare the U.S. and other countries. For example, this calculation puts economic welfare in the United Kingdom at 97% of U.S. levels, but estimates Mexican well-being at 22%. The Jones-Klenow measure can also assess an economy’s performance over time. According to this measure, as of the early-to-mid-2000s, the U.S. had the highest economic welfare of any large country. Since 2007, economic welfare in the U.S. has continued to improve. However, the pace of improvement has slowed markedly. Methodologically, the lesson from the Jones-Klenow research is that economic welfare is multi-dimensional. Their approach is flexible enough that in principle other important quality-of-life changes could be incorporated—for example, decreases in total emissions of pollutants and declines in crime rates. What does the author say about the Jones-Klenow method?___

Economically speaking, are we better off than we were ten years ago? Twenty years ago? In their thirst for evidence on this issue, commentators seized on the recent report by the Census Bureau, which found that average household income rose by 5.2% in 2015. Unfortunately, that conclusion puts too much weight on a useful, but flawed and incomplete, statistic. Among the more significant problems with the Census’s measure are that: 1) it excludes taxes, transfers, and compensation like employer-provided health insurance; and 2) it is based on surveys rather than data. Even if precisely measured, income data exclude important determinants of economic well-being, such as the hours of work needed to earn that income. While thinking about the question, we came across a recently published article by Charles Jones and Peter Klenow, which proposes an interesting new measure of economic welfare. While by no means perfect, it is considerably more comprehensive than average income, taking into account not only growth in consumption per person but also changes in working time, life expectancy, and inequality. Moreover, it can be used to assess economic performance both across countries and over time. The Jones-Klenow method can be illustrated by a cross-country example. Suppose we want to compare the economic welfare of citizens of the U.S. and France in 2005. In 2005, as the authors observe, real consumption per person in France was only 60% as high as the U.S., making it appear that Americans were economically much better off than the French on average. However, that comparison omits other relevant factors: leisure time, life expectancy, and economic inequality. The French take longer vacations and retire earlier, so typically work fewer hours; they enjoy a higher life expectancy, presumably reflecting advantages with respect to health care, diet, lifestyle, and the like; and income and consumption are somewhat more equally distributed there than in the U.S. Because of these differences, comparing France’s consumption with the U.S.’s overstates the gap in economic welfare. Similar calculations can be used to compare the U.S. and other countries. For example, this calculation puts economic welfare in the United Kingdom at 97% of U.S. levels, but estimates Mexican well-being at 22%. The Jones-Klenow measure can also assess an economy’s performance over time. According to this measure, as of the early-to-mid-2000s, the U.S. had the highest economic welfare of any large country. Since 2007, economic welfare in the U.S. has continued to improve. However, the pace of improvement has slowed markedly. Methodologically, the lesson from the Jones-Klenow research is that economic welfare is multi-dimensional. Their approach is flexible enough that in principle other important quality-of-life changes could be incorporated—for example, decreases in total emissions of pollutants and declines in crime rates. What do Jones and Klenow think of the comparison between France and the U.S. in terms of real consumption per person?___

Economically speaking, are we better off than we were ten years ago? Twenty years ago? In their thirst for evidence on this issue, commentators seized on the recent report by the Census Bureau, which found that average household income rose by 5.2% in 2015. Unfortunately, that conclusion puts too much weight on a useful, but flawed and incomplete, statistic. Among the more significant problems with the Census’s measure are that: 1) it excludes taxes, transfers, and compensation like employer-provided health insurance; and 2) it is based on surveys rather than data. Even if precisely measured, income data exclude important determinants of economic well-being, such as the hours of work needed to earn that income. While thinking about the question, we came across a recently published article by Charles Jones and Peter Klenow, which proposes an interesting new measure of economic welfare. While by no means perfect, it is considerably more comprehensive than average income, taking into account not only growth in consumption per person but also changes in working time, life expectancy, and inequality. Moreover, it can be used to assess economic performance both across countries and over time. The Jones-Klenow method can be illustrated by a cross-country example. Suppose we want to compare the economic welfare of citizens of the U.S. and France in 2005. In 2005, as the authors observe, real consumption per person in France was only 60% as high as the U.S., making it appear that Americans were economically much better off than the French on average. However, that comparison omits other relevant factors: leisure time, life expectancy, and economic inequality. The French take longer vacations and retire earlier, so typically work fewer hours; they enjoy a higher life expectancy, presumably reflecting advantages with respect to health care, diet, lifestyle, and the like; and income and consumption are somewhat more equally distributed there than in the U.S. Because of these differences, comparing France’s consumption with the U.S.’s overstates the gap in economic welfare. Similar calculations can be used to compare the U.S. and other countries. For example, this calculation puts economic welfare in the United Kingdom at 97% of U.S. levels, but estimates Mexican well-being at 22%. The Jones-Klenow measure can also assess an economy’s performance over time. According to this measure, as of the early-to-mid-2000s, the U.S. had the highest economic welfare of any large country. Since 2007, economic welfare in the U.S. has continued to improve. However, the pace of improvement has slowed markedly. Methodologically, the lesson from the Jones-Klenow research is that economic welfare is multi-dimensional. Their approach is flexible enough that in principle other important quality-of-life changes could be incorporated—for example, decreases in total emissions of pollutants and declines in crime rates. What is an advantage of the Jones-Klenow method?___

Economically speaking, are we better off than we were ten years ago? Twenty years ago? In their thirst for evidence on this issue, commentators seized on the recent report by the Census Bureau, which found that average household income rose by 5.2% in 2015. Unfortunately, that conclusion puts too much weight on a useful, but flawed and incomplete, statistic. Among the more significant problems with the Census’s measure are that: 1) it excludes taxes, transfers, and compensation like employer-provided health insurance; and 2) it is based on surveys rather than data. Even if precisely measured, income data exclude important determinants of economic well-being, such as the hours of work needed to earn that income. While thinking about the question, we came across a recently published article by Charles Jones and Peter Klenow, which proposes an interesting new measure of economic welfare. While by no means perfect, it is considerably more comprehensive than average income, taking into account not only growth in consumption per person but also changes in working time, life expectancy, and inequality. Moreover, it can be used to assess economic performance both across countries and over time. The Jones-Klenow method can be illustrated by a cross-country example. Suppose we want to compare the economic welfare of citizens of the U.S. and France in 2005. In 2005, as the authors observe, real consumption per person in France was only 60% as high as the U.S., making it appear that Americans were economically much better off than the French on average. However, that comparison omits other relevant factors: leisure time, life expectancy, and economic inequality. The French take longer vacations and retire earlier, so typically work fewer hours; they enjoy a higher life expectancy, presumably reflecting advantages with respect to health care, diet, lifestyle, and the like; and income and consumption are somewhat more equally distributed there than in the U.S. Because of these differences, comparing France’s consumption with the U.S.’s overstates the gap in economic welfare. Similar calculations can be used to compare the U.S. and other countries. For example, this calculation puts economic welfare in the United Kingdom at 97% of U.S. levels, but estimates Mexican well-being at 22%. The Jones-Klenow measure can also assess an economy’s performance over time. According to this measure, as of the early-to-mid-2000s, the U.S. had the highest economic welfare of any large country. Since 2007, economic welfare in the U.S. has continued to improve. However, the pace of improvement has slowed markedly. Methodologically, the lesson from the Jones-Klenow research is that economic welfare is multi-dimensional. Their approach is flexible enough that in principle other important quality-of-life changes could be incorporated—for example, decreases in total emissions of pollutants and declines in crime rates. What can we infer from the passage about American people’s economic well-being?___

大学生的成才目标是___。

现代人才素质的灵魂是___。

___是人才素质的基础.

世界政治格局发展的必然趋势是___。

在全面发展的教育中德、智、体、美是缺一不可，统一存在的，其中处于主导地位的是___。

时代精神的内涵十分丰富，其中___居于核心地位。

民族精神是一个民族赖以生存和发展的精神支撑。中华民族在五千年的发展中所形成的伟大民族精神的核心是___。

下列名言反映中华民族是一个艰苦奋斗的民族的有___。

___是人才素质的基本内容

10。___是我们立党立国的根本指导思想

衡量大学生全面发展的一个重要标准是___

2016中国CML指南定义一线格列卫治疗失败的标准为3个月无任何CyR。

2016中国CML指南定义一线格列卫治疗失败的标准为6个月未达到CCyR。

2016中国CML指南定义一线格列卫治疗最佳反应的标准为12个月达到CCyR或BCR-ABL（IS）≤1%。

2016中国CML指南定义一线格列卫治疗最佳反应的标准为12个月获得MMR。

2016中国CML指南定义一线格列卫治疗最佳反应的标准为6个月至少达到PCyR或BCR-ABL（IS）≤10%。

2016中国CML指南推荐，每3个月进行1次分子学检测，直至获得稳定MMR即可停止监测

CML-CP患者获得部分细胞遗传学反应的定义为Ph+ 1%-35%。

CML-CP患者获得完全分子学反应的定义为定量PCR检测不到BCR-ABL转录本，巢式PCR检测阴性。

CML-CP患者未获得细胞遗传学反应的定义为Ph+ >95% 。

CML-IV研究中位随访3年时，无患者出现证实的MR4.5进展

CML常规染色体分析，检测20-30个有丝分裂中期的骨髓细胞中有多少Ph+细胞。

CML患者FISH检测的样本来源于外周血/骨髓，检测敏感度为0.5-5%，可用于CML诊断、常规细胞遗传学疗效和微小残留病变检测。

CML患者RT-PCR检测的样本来源于外周血/骨髓，检测敏感度可达0.0001-0.001%，可用于常规微小残留病变和融合基因断裂点检测。

CML患者分子学水平检测的疗效结果为MMR和CMR等。

CML患者染色体核型分析样本来源于外周血，检测敏感度仅有1-5%，可用于CML诊断和分析费城染色体之外的染色体异常。

CML患者细胞遗传学水平检测的疗效结果描述为MMR和CMR等。

CML治愈之路是诺华和CML社区的一项长期合作，包括对CML更好的理解，改进检测和监测手段和优化治疗方案，从而使患者实现更好的转归。

CMR是指完全分子学反应。

ENESTcmr研究中伊马替尼进行一线治疗的CML患者，较继续使用伊马替尼，更多的患者通过二线达希纳获得DMR。

ENESTfreedom 研究中，由于不稳定DMR没有尝试TFR资格的患者经达希纳治疗1年后可获得尝试TFR的资格。

ENESTnd标志性分析中，3个月时获得BCR-ABLIS≤10%与60个月时更佳的OS无关

ENESTnd标志性分析中，与伊马替尼相比，达希纳一线治疗更早获得分子学反应。

ENESTnd研究中，从第一年至第五年的随访中，达希纳和伊马替尼组累积的MR4.5相差的比例保持完全不变。

ENESTnd研究中，与伊马替尼相比，达希纳一线治疗组疾病进展至AP/BC显著更少。

ENESTnd研究中，在5年随访中，所有时间点达希纳组MMR的比例始终高于伊马替尼组。

ENESTnd研究中在伊马替尼治疗12个月内的MMR率为27%。

ENESTxtnd研究发现一线达希纳治疗反应欠佳或治疗失败后增加达希纳剂量可获得较高的MMR率。

IRIS研究随访10年, 32% 伊马替尼治疗患者由于不满意治疗反应中断治疗，＞10%由于不良事件。

NCCN发表的关于TKI尝试停用之前需满足MR4 ≥ 3 年

NCCN指南中，CML-CP患者获得主要分子学反应的定义为定量PCR检测不到BCR-ABL转录本。

STIM格列卫停药研究。

STIM是指停用格列卫。

TKI治疗第二肿瘤发生率与普通人群相当。

达到DMR是实现停药的门槛。

达到EMR（3个月 BCR-ABL≤10%）能改善最佳长期结局，并为将来保持无疾病进展提供最佳机会。

达希纳不可以与羟基脲或阿那格雷联用。

达希纳代谢产物少部分经肾脏代谢，所以对于肾损害患者无需进行剂量调整？

达希纳服用时，如果错过给药，患者不得另外补充剂量，而是按照处方服用下一次剂量。

达希纳及其代谢产物只有少部分经肾脏排泄，所以预计肾损害患者并不会出现总体清除率的降低。对肾损害患者不需要进行剂量调整？

达希纳胶囊服用时，可以咀嚼或吮吸，可以打开胶囊。