【单选题】
呼吸作用是生物体内的有机物在细胞内经过一系列的氧化分解，在释放出能量的同时，最终生成的主要是 ___
A. 氧气
B. 二氧化碳
C. 氮气
D. 不知道
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相关试题
【单选题】
晚上，植物与动物都不应该放入卧室内，要将其移到卧室外，这是因为它们会降低卧室内的___
A. 空气温度
B. 空气湿度
C. 氧气浓度
D. 氮气浓度
【单选题】
杂交优势往往在第几代杂交种子中表现最明显。___
【单选题】
以下不属于人体增强技术类型的是___
A. 短暂性增强
B. 持续性增强
C. 结构性增强
D. 内在增强
【单选题】
大陆漂移学说是由谁提出的___
A. 勒比雄
B. 魏格纳
C. 赫斯
D. 李四光
【单选题】
(1)Whieh of the following descriptions about the characteristics of physiology is wrong？___
A. It is the study of how living organisms work.
B. It illustrates the discipline of the development and the evolution of disease and the essence of disease.
C. It is to study the living phenomena and the function activities of living organs.
D. It is to explain how they are regulated and integrated.
【单选题】
(2) Which of the following are specialized in producing force and movement?___
A. muscle cells
B. connective tissues
C. nerve cells
D. epithelial cells
【单选题】
(3)The fluid environment surrounding each cell is called the___
A. intracellular fluid
B. intracellular fluid
C. internal environment
D. external environment
【单选题】
(4) Which of the following is not the fundamental characteristic of living organisms?___
A. metabolism
B. adaption
C. reproduction
D. passive diffusion
【单选题】
(5)Whicl of the following is a physiological process with negative feedback?___
A. blood coagulation
B. process of passing urine
C. sino-aortic baroreceptor reflex
D. process of parturition
【单选题】
(6)Which of the following is not the characteristic of regulation by hormone?___
A. diffusenin nature
B. longer in duration
C. accurate in action
D. action in overcorrection
【单选题】
7)Which of the following is not the characteristic of cells?___
A. They are bound by the plasma membrane
B. They have the ability to break down large molecules to smaller ones to Liberate energy for their activities
C. They possess a nucleus which contains genetic information in the form of deoxyribonucleicacid(DNA).
D. Living cells can not transform materials.
【单选题】
8)The breakdown of large molecules to smaller ones is called___
A. respiration
B. anabolism
C. catabolism
D. absorption
【单选题】
9) Which of the following descriptions about the characteristics of nervous regulation is wrong?___
A. It responds fast
B. It acts exactly
C. It responds slowly.D.
D. uration is short
【单选题】
10)Which of the following descriptions about the control of body function is wrong?___
A. Homeostasis is kept by feedback control.
B. Negative feedback minimizes the changes, leading to stability.
C. Positive feedback is not useful.
D. Feed-forward makes human body foresee and adapt itself to the environment promptly.
【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
推荐试题
【单选题】
DNA复制时下列哪一种酶是不需要的? ___
A. D D DP
B. D D RP
C. RD DP
D. 连接酶
E. 拓扑异构酶
【单选题】
以下哪些代谢过程需要以RNA为引物? ___
A. 体内DINA复制
B. 转录
C. RNA复制
D. 翻译
E. 反转录
【单选题】
RNA 引物在DNA复制过程中的作用是___
A. 提供起始模板
B. 激活引物酶
C. 提供复制所需的5'一磷酸
D. 提供复制所需的3'- 羟基
E. 激活DNA-po1Ⅲ
【单选题】
冈崎片段是指___
A. 复制起始时，RNA聚合酶合成的
B. 两个复制起始点之间的DNA片段
C. DNA半不连续复制时出现的DNA片段
D. DNA连续复制时出现的DNA片段
E. E.coli复制起始点oriC的跨度为245bp片段
【单选题】
DNA复制过程中参与冈崎片段之间连接的酶有___
A. RNA酶
B. DNA-p11Ⅲ
C.
D. naA蛋白
【单选题】
合酶;⑤DNA连接酶参加，其作用的顺序是___
A. 4→3→1→2→5
B. 2→3→4→1→5
C. 4→2→1→5→3
D. 4→2→1→3→5
E. 2→4→1→3→5
【单选题】
下列关于逆转录酶的叙述，正确的是___
A. 以mRNA为模板，催化合成RNA的酶
B. 其催化合成反应的方向是3'→5'
C. 催化合成时需先合成冈崎片段
D. 此酶具有RNase活性
【单选题】
逆转录的遗传信息流向是___
A. DNA→DNA
B. DNA→RNA
C. RNA→DNA
D. RNA-蛋白质
E. RNA→RNA
【单选题】
RNA指导的DNA合成是___
A. 复制
B. 转录
C. 反转录
D. 翻译
E. 整合
【单选题】
关于DNA聚合酶的叙述，错误的是___
A. 需模版DNA
B. 需引物RNA
C. 延伸方向为5'→3'
D. 以NTP为原料
E. 具有3'→5'外切酶的活性
【单选题】
DNA复制的特点___
A. 单向复制
B. 连续复制
C. 全保留复制
D. 有特定起点
E. 由遗传密码控制
【单选题】
反转录是指___
A. 以RNA为模板合成RNA
B. 以DNA为模板合成DNA
C. 以DNA为模板合成RNA
D. 以RNA为模板合成蛋白质
E. 以RNA为模板合成DNA
【单选题】
能以RMA为模板催化合成与RKA互补的DNA (cDNA)的酶称为___
A. DNA聚合酶Ⅰ
B. DNA聚合酶Ⅱ
C. DNA聚合酶Ⅲ
D. RVA聚合酶
E. 反转录酶
【单选题】
下列能导致框移的突变是___
A. A取代C
B. G取代A
C. 缺失三个核苷酸
D. 插入一个核苷酸
E. 插入三个核苷酸
【单选题】
紫外线照射引起DNA形成常见的嘧啶二聚体是___
A. C-C
B. C-T
C. T-U
D. T-T
E. C-T
【单选题】
细胞内最重要和有效的修复方式是___
A. 光修复
B. 切除修复
C. 重组修复
D. SOS修复
E. 错配修复
【单选题】
下列不参与DNA的切除修复过程的是___
A. DNA聚合酶Ⅰ
B. DNA聚合酶Ⅲ
C. 核酿内切酶
D. DNA连接酶
E. 解螺旋酶
【单选题】
与修复过程缺陷有关的疾病是___
A. 黄嘌呤尿症
B. 着色性干皮病
C. 卟啉病
D. 痛风
E. 黄疸
【单选题】
在大多数DNA修复中，牵涉到四步序列反应，这四步序列反应的次序是___
A. 识别、切除、再合成、再连接
B. 再连接、再合成、切除、识别
C. 切除、再合成、再连接、识别
D. 识别、再合成、再连接、切除
E. 切除、识别、再合成、再连接
【单选题】
DNA损伤后切除修复的说法中错误的是___
A. 修复机制中以切除修复最为重要
B. 切除修复包括有重组修复及SOS修复
C. 切除修复包括糖基化酶起始作用的修复
D. 切除修复中有以UvrABC进行的修复
E. 是对DNA损伤部位进行切除，，随后进行正确合成的修复
【单选题】
镰刀状红细胞贫血其β链有关的突变是___
A. 插入
B. 断裂
C. 缺失
D. 交联
E. 点突变
【单选题】
DNA突变和DNA修复之间的平衡在生物进化中发挥着重要的作用，这是因为___
A. DNA 损伤过于严重总是导致物种的灭绝
B. DNA修复需要DNA聚合酶Ⅲ去纠正DNA的损伤
C. DNA损伤和DNA修复是细胞中互不相关的事件
D. 胞嘧啶的脱氨基反应是一件罕见的事件，但却是引起突变的
E. 生殖细胞中的DNA突变如果没有被修复，只可以允许自然选择
【单选题】
关于DNA损伤的切除修复，不正确的是___
A. DNA 的一条链损伤，互补链完整
B. 由限制性内切酶识别并切除损伤的DNA片段
C. DNA链中的TT二聚体可切除修复
D. 切除DNA损伤片段，5'→3'合成互补新链
E. 需DNA内切酶、外切酶及DNA聚合酶等催化
【单选题】
11,突变___
A. 是由有害因素引起的有害结果
B. 是进化的基础
C. 反映遗传的保守性
D. 自然突变频率很低，可以忽略
E. 一定会引起功能受损
【单选题】
点突变引起的后果是___
A. DNA降解
B. 氨基酸读码可改变
C. DNA复制停顿
D. 转录终止
E. 氨基酸缺失
【单选题】
DNA损伤后原核生物切除修复过程需要: 1. DINA连接酶: 2. DNA聚合酶Ⅰ; 3.Uvr 蛋白类___
A. 1,2,3
B. 3,2,1
C. 2,3,1
D. 2,1,3
E. 3,1,2
【单选题】
嘧啶二聚体的解聚方式靠___
A. SOS修复
B. 光修复酶的作用
C. 原核生物的切除修复
D. 重组修复
E. 真核生物的切除修复
【单选题】
除DNA复制外，属于RNA生物合成的还有___
A. 半保留复制
B. 半不连续复制
C. 不对称转录
D. 反转录
E. 翻译
【单选题】
2真核细胞的转录发生在___
A. 缁胞浆
B. 内质网
C. 线粒体
D. 细胞核
E. 核蛋白体
【单选题】
转录的模板链是___
A. 编码链
B. 前导链
C. DNA的两条链
D. 基因组DNA中的一条链
E. 基因DNA中的-条链
【单选题】
转录需要的原料为___
A. NMP
B. NTP
C. dNMP
D. dNDP
E. dNTP
【单选题】
转录需要的酶有___
A. 引物酶
B. 依赖DNA的DNA聚合酶(DDPD）
C. 依赖DNA的RNA聚合酶(DDRP)
D. 依赖RNA的DNA聚合酶(RDDP)
E. 依赖RNA的RNA聚合酶(RDRP)
【单选题】
以下关于转录的概念，不正确的是___
A. 以DNA为模板合成RNA的过程
B. RNA的生物合成过程叫做转录
C. 将染色休DNA分子中储存的遗传信息转为RNA碱基排列顺序的过程
D. 转录在遗传信息传递中起中介作用
E. 遗传信息的表达包括转录形成RNA及由mRNA指导的蛋白质生物合成
【单选题】
以下有关转录叙述，不正确的是___
A. DNA双链中指导RNA合成的链是模板链
B. DNA双链中不指导RNA合成的链是编码链
C. 能转录出RNA的DNA序列称为结构基因
D. 染色体DNA双链中仅一条链可转录
E. 基因DMA双链中一条链可转录，另一条链不转录
【单选题】
原核生物体内催化RNA延长的是___
A. α因子
B. α、β亚基
C. ,α、β、β'亚基
D. α2. β、β'亚基
E. RNA-po1全酶
【单选题】
利福平(或利福霉素)抑制结核函的机制是___
A. 抑制细胞DNA聚合酶
B. 抑制细菌DNA聚合酶
C. 抑制细胞RNA聚合酶
D. 抑制细菌RNA聚合酶
E. 抑制细菌蛋白质合成
【单选题】
利福平(或利福霉素)抑制结核菌的机制是它抑制了菌体RNA聚合酶中的___
A. σ亚基
B. β亚基
C. β'亚基
D. σ亚基
E. ρ因子
【单选题】
在DNA分子中，转录起始的5'上游端___
A. 原核生物-35区存在TATA盒是RNA-po1识别的位点
B. 原核生物-10区存在TATA盒是RNA-po1结合的位点
C. 原核生物-35区存在TTGACA序列是RNA-po1结合的位点
D. 原核生物-10区存在TTGACA序列是RNA-po1识别的位点
E. 真核生物不存在TATA盒
【单选题】
12,哪项不是原核生物转录终止可依赖的因素___
A. ρ因子
B. σ因子
C. 转录产物RNA3' 端出现可对折互补序列，形成茎环结构
D. 转录产物RMA3嘴出现寡聚u,与模板DINA 结合力小
E. 终止因子与产物RENA结合促使其与DNA分离
【单选题】
真核细胞中由RNA po1Ⅲ催化生成的产物是___
A. tRNA 前体
B. mRNA
C. hnRNA
D. snRNA
E. 45sRNA
