【单选题】
8)The breakdown of large molecules to smaller ones is called___
A. respiration
B. anabolism
C. catabolism
D. absorption
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【单选题】
9) Which of the following descriptions about the characteristics of nervous regulation is wrong?___
A. It responds fast
B. It acts exactly
C. It responds slowly.D.
D. uration is short
【单选题】
10)Which of the following descriptions about the control of body function is wrong?___
A. Homeostasis is kept by feedback control.
B. Negative feedback minimizes the changes, leading to stability.
C. Positive feedback is not useful.
D. Feed-forward makes human body foresee and adapt itself to the environment promptly.
【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
推荐试题
【多选题】
涉密办公自动化设备禁止接入___
A. 涉密计算机和信息系统
B. 单位内部非涉密计算机或信息系统
C. 国际互联网
D. 公共信息系统
【多选题】
关于涉密计算机的使用，以下行为中错误的有___
A. 根据工作需要，可以安装摄像头
B. 可以安装FTP服务器端，面向系统用户提供涉密文档资料下载和上传
C. 在计算机上安装个人硬盘，换成可刻录光驱进行文件的输入输出
D. 使用普通优盘直接连接涉密计算机
【多选题】
下列说法正确的是___
A. 涉密信息系统经本单位保密工作机构测试后即可投入使用
B. 涉密信息系统投入运行前应当经过国家保密行政管理部门审批
C. 涉密计算机重装操作系统后可降为非涉密计算机使用
D. 未经单位信息管理部门批准不得自行重装操作系统
【多选题】
关于国家秘密的保密期限，下列说法正确的是___
A. 国家秘密的保密期限，除另有规定外，绝密级不超过四十年，机密级不超过三十年，秘密级不超过二十年
B. 机关单位应当根据工作的需要，确定具体的保密期限、解密时间或者解密条件
C. 机关单位对工作中需要保密的事项，根据工作需要决定公开的，正式公布时即视为解密
D. 不能确定期限的国家秘密，应当确定解密的条件
【多选题】
下列说法正确的是___
A. 国家秘密载体的制作、收发、传递、使用、复制、保存、维修和销毁，应当符合国家保密规定
B. 绝密级国家秘密载体应当在符合国家保密标准的设施、设备中保存，并指定专人管理
C. 经原定密机关、单位或上级机关批准，可以复制和摘抄
D. 收发、传递和携带外出，应当指定人员负责，并采取必要的安全措施
【多选题】
关于涉密信息系统，下列说法正确的是___
A. 存储、处理国家秘密的计算机信息系统应按照涉密程度实现分级保护
B. 涉密信息系统应当按照国家保密标准配备保密设施、设备
C. 相关保密设备的采购，应当提前与厂商预约或定制
D. 涉密信息系统应当按照规定，经检查合格后，方可投入使用
【多选题】
关于涉密人员管理，下列说法正确的是___
A. 涉密人员应当具备良好的政治素质和品行，具有胜任涉密岗位所要求的能力
B. 有关机关认为涉密人员出境将对国家安全造成危害或者对国家利益造成重大损失的，不得批准出境
C. 涉密人员在脱密期内，应当履行保密义务，不得违反规定就业，不得以任何方式泄露国家机密
D. 涉密人员的合法权益受法律保护
【多选题】
国家秘密的基本范围包括___
A. 国家实务重大决策中的秘密事项
B. 大型央企的商业机密
C. 外交和外事活动中的秘密事项
D. 国民经济和社会发展中的秘密事项
【多选题】
关于涉密人员脱密期，下列说法正确的是___
A. 涉密人员脱密期自当事人向机关、单位提交离岗申请之日起计算
B. 核心涉密人员的脱密期为5年至8年
C. 对特殊的高知密人员，可以依法设定超过规定期限的脱密期
D. 脱密期内，不得到境外驻华机构、组织或者外资企业工作
【多选题】
涉密人员需报告的重大事项有___
A. 与境外人员结婚的
B. 接受境外亲属人员资助的
C. 配偶子女获得境外永久居留资格或者获得外国国籍的
D. 购买境外企业股份及有价债券的
【多选题】
保密工作应当坚持以下哪些原则___
A. 最小化原则
B. 法制化原则
C. 全程化原则
D. 精准化原则
【判断题】
核心涉密岗位是指产生、管理、掌握或者经常处理绝密级事项的工作岗位。
【判断题】
经审查合格，进入涉密岗位的人员须按规定签订保密承诺书，承担相应的保密责任。
【判断题】
涉密人员与境外人员通婚或者接受境外机构、组织资助的应当向单位报告。
【判断题】
涉密人员本人或者直系亲属获得境外永久居留权以及取得外国国籍的应当向单位报告。
【判断题】
涉密人员在脱密期内不得到境外驻华机构、组织或者外资企业工作，但可以为境外组织或人员提供劳务咨询或其他服务。
【判断题】
国家秘密的保密期限已满的，可以自行解密。
【判断题】
涉密人员离开涉密岗位后，就不再对本人在原涉密岗位上知悉的国家秘密事项承担保密义务.
【判断题】
涉密人员出境应当经有关部门批准，有关机关认为涉密人员出境将对国家安全造成危害或者对国家利益造成重大损失的，不得批准出境。
【判断题】
配偶、子女和本人都是涉密人员，互相谈涉密事项没有关系。
【判断题】
保密范围定得越宽，密级越高，越有利于国家秘密的安全。
【判断题】
国家秘密的标志为★，★前标注密级，★后标注保密期限。
【判断题】
摘录、引用密件中属于国家秘密的内容，应当以其中最高密级和最长保密期限作出标志。
【判断题】
国家秘密事项的密级和保密期限一经确定，就不能改变。
【判断题】
国家秘密的保密期限，除有特殊规定外，绝密级事项不超过20年，机密级事项不超过10年，秘密级事项不超过5年。
【判断题】
企业的技术成果被确定为国家秘密后，在保密期限内不得擅自解密和对外提供。
【判断题】
复制绝密级涉密载体应当履行审批手续，经本机关或本单位负责人批准，加盖复制戳记，视同原件管理，并进行登记。
【判断题】
普通手机处于关机状态下，不存在泄密隐患。
【判断题】
因工作需要随身携带密件、密品外出时，不得进入购物、餐饮娱乐等公共场所。
【判断题】
密品是指直接含有国家秘密信息的设备或者产品。
【判断题】
涉密存储介质经文件删除并格式化处理后，仍不得作为非密介质使用。
【判断题】
涉密计算机和移动存储介质未经国家指定的专业销密点销密，不得自行淘汰处理。
【判断题】
在涉密场所使用的与国际互联网或者其他公共网络连接的计算机不得安装视频、音频等输入装置。
【判断题】
确因工作需要，可以使用私人计算机处理涉密文件，但要与国际互联网断开连接，待处理完涉密信息后可与互联网连接。
【判断题】
召开涉及国家秘密的会议，使用无线扩音、通信设备不能把音量开得太大。
【判断题】
在对外交往与合作中急需提供国家秘密事项的，可以先提供，后补办手续。
【判断题】
发现国家秘密载体在使用中下落不明，应当在8小时内向本单位保密工作机构报告，向上级报告不应超过24小时。
【判断题】
保密行政管理部门对保密检查中发现的非法获取、持有的国家秘密载体，应当予以收缴。
