【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
查看试卷，进入试卷练习
微信扫一扫，开始刷题
相关试题
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
【单选题】
（1）地球表层覆盖着很多圈层，其中最厚的圈层是 ___
A. 岩石圈
B. 水圈
C. 大气圈
D. 生物圈
【单选题】
（2）目前受人类影响最强烈的地球圈层部位主要在大气圈底层、岩石圈上层以及 ___
A. 生物圈表层
B. 生物圈中层
C. 水圈底层
D. 水圈全部
【单选题】
（3）生物圈的范围为___
A. 大气圈、水圈和岩石圈的全部
B. 大气圈和水圈的全部、岩石圈的上部
C. 大气圈的底部、水圈和岩石圈的全部
D. 大气圈的底部、水圈的全部和岩石圈的上部
【单选题】
（4）地球上最大的生态系统是 ___
A. 森林生态系统
B. 生物圈
C. 海洋生态系统
D. 城市生态系统
推荐试题
【单选题】
___
A. 震颤产生机制与杂音相同，有震颤一定可听到杂音
B. 听到杂音不一定能触到震颤
C. 狭窄越重震颤越强，过度狭窄可无震颤
D. 震颤可分为收缩期震颤、舒张期震颤及连续性震颤
【单选题】
___
A. 主动脉瓣关闭不全并狭窄
B. 动脉导管未闭
C. 肺动脉瓣关闭不全并狭窄
D. 二尖瓣关闭不全并狭窄
【单选题】
___
A. 球型心
B. 靴型心
C. 烧瓶样心
D. 梨型心
【单选题】
___
A. 摩擦感消失不一定提示病情改善，也可能病情加重
B. 触及部位在心尖部
C. 收缩期易触及
D. 吸气末明显
【单选题】
___
A. 糖尿病
B. 肝性腹水
C. 神经性厌食
D. 恶性肿瘤
【单选题】
___
A. 腹壁静脉常以脐为中心，流向四方
B. 脐水平线以上腹壁静脉血流方向自上而下，脐水平线以下腹壁静脉血流方向自上而下
C. 脐水平线以上腹壁静脉血流方向自下而上，脐水平线以下腹壁静脉血流方向自下而上
D. 脐水平线以上腹壁静脉血流方向自上而下，脐水平线以下腹壁静脉血流方向自下而上
【单选题】
___
A. 胃穿孔
B. 结核性腹膜炎
C. 腹腔出血
D. 急性阑尾炎
【单选题】
___
A. 急性肝炎
B. 肝癌
C. 肝脓肿
D. 急性肝炎
【单选题】
___
A. 脾明显肿大时，应加作第Ⅱ线测量和第Ⅲ线测量
B. 第Ⅲ 线测量指脾右缘与前正中线距离
C. 第Ⅰ线测量指左肋缘至脾下缘的距离
D. 脾轻度肿大只作第Ⅰ线测量
【单选题】
___
A. 急性胆囊炎
B. 急性肝炎
C. 急性胃炎
D. 急性胰腺炎
【单选题】
___
A. 组织缺镁
B. 组织缺钙
C. 真菌感染
D. 组织缺铁
【单选题】
___
A. 慢性缺氧
B. 组织缺镁
C. 组织缺钙
D. 真菌感染
【单选题】
___
A. 脊柱过度前凸
B. 脊柱弓形畸形
C. 脊柱姿势性侧凸
D. 脊柱器质性侧凸
【单选题】
___
A. (B)(A)(B)inski 征阳性
B. Kerning 征阳性
C. Oppenheim 征阳性
D. Gor(D)on's 征阳性
【单选题】
___
A. 3 级
B. 6 级
C. 5 级
D. 2 级
【单选题】
___
A. 脊柱侧弯
B. 脊柱前屈
C. 脊柱压痛
D. 脊柱后伸
【单选题】
___
A. 膝部摩擦感
B. 握茶杯姿势
C. 膝反张
D. “X”形腿
【单选题】
___
A. 阵挛
B. (C)h(A)(D)(D)o(C)k 征
C. Hoffm(A)nn 征
D. Kernig 征
【单选题】
___
A. 肌张力是指静息状态下的肌肉紧张度
B. 肌张力增加时可表现为关节过伸
C. 除肌肉的收缩力外，还可以动作的幅度与速度来衡量肌力
D. 肌力是指肢体作某种主动运动时肌肉最大的收缩力
【单选题】
___
A. PR间期逐渐延长至QRS脱落
B. PR间期延长，PR≥ 0.20秒
C. PR固定，部分P 波后无QRS波
D. PR间期缩短，QRS增宽且有δ波
【单选题】
___
A. 提前出现一个变异的P波
B. PR间期 < 0.12秒，代偿间期不完全
C. PR间期＞ 0.12秒，代偿间期不完全
D. QRS波一般不变形
【单选题】
___
A. 提早出现一个宽大畸形的QRS－T 波群
B. T波与主波方向相反
C. 早搏的QRS波前有P波
D. 有完全性代偿间期
【单选题】
___
A. 右房肥大
B. 双室肥大
C. 左室肥大
D. 左房肥大
【单选题】
___
A. I、(A)VL
B. V1～ V5
C. V1～V3
D. II、III、(A)VF
【单选题】
___
A. 心外膜面缺血，出现与正常相反的T波，如下壁缺血出现II、 III、(A)VF倒置T波
B. 心内膜下心肌缺血，出现与QRS主波方向一致的高大T波
C. 心肌缺血时，下移的ST段与R波夹角≥90o
D. ST段弓背向上抬高
【单选题】
___
A. QRS波群增宽
B. 左室高电压
C. 心电轴显著左偏
D. T波倒置明显
【单选题】
___
A. I、(A)VL、V5
B. V7、V8
C. II、III、(A)VF
D. V1、V2、V3
【单选题】
___
A. Q波宽度≥ 0.04 秒，深度≥1/4R，并排除个别导联的正常变异
B. (A)VR导联上出现的QS波
C. Q波宽度≥0.04秒
D. V1导联上出现的QS波
【多选题】
病史采集的“ 临床场景”的画面是___
A. 患者
B. 患者及其家庭、工作、社会关系及朋友
C. 陪人
D. 医生
【多选题】
现病史的结构应包括___
A. 起病情况、病因与诱因
B. 病情的发展与演变
C. 伴随病状和一般情况
D. 诊治经过
【单选题】
网络管理员在网络中捕获到了一个数据帧，其目的MAC地址是01-00-5E-A0-B1-C3。关于该MAC地址的说法正确的是（）___。
A. 它是一个单播MAC地址
B. 它是一个广播MAC地址
C. 它是一个组播MAC地址
D. 它是一个非法MAC地址
【单选题】
以下哪项不是CSMA/CD的工作原理？___
A. 边发边听
B. 延迟固定时间后重发
C. 冲突停发
D. 随机延迟后重发
E. 先听后发
【单选题】
主机的IPv4地址为200.200.200.201/30，拥有下列哪个IPv4地址的主机和其通信不需要经过路由器转发？___
A. 200.200.200.1
B. 200.200.200.202
C. 200.200.200.200
D. 200.200.200.203
【单选题】
网络管理员在网络中捕获到了一个数据帧，其目的MAC地址是01-00-5E-A0-B1-C3。关于该MAC地址的说法正确的是（）___。
A. 它是一个单播MAC地址
B. 它是一个广播MAC地址
C. 它是一个组播MAC地址
D. 它是一个非法MAC地址
【单选题】
以下哪项不是CSMA/CD的工作原理？___
A. 边发边听
B. 延迟固定时间后重发
C. 冲突停发
D. 随机延迟后重发
E. 先听后发
【单选题】
主机的IPv4地址为200.200.200.201/30，拥有下列哪个IPv4地址的主机和其通信不需要经过路由器转发？___
A. 200.200.200.1
B. 200.200.200.202
C. 200.200.200.200
D. 200.200.200.203
【单选题】
VRP操作系统命令划分为访问级、监控级、配置级、管理级4个级别。能运行各种业务配置命令但不能操作文件系统的哪一级？___
A. 访问级
B. 监控级
C. 配置级
D. 管理级
【单选题】
VRP界面下，使用命令delete或unreserved vrpcfg.zip 无法删除文件，必须在回收站中清空，才能彻底删除文件。___
【单选题】
9现有交换机MAC地址表如下，下列说法正确的有？___
A. MAC地址5489-9885-1838是由管理员手工配置
B. MAC地址5489-9811-0b49是由管理员手工配置
C. MAC地址5489-3891-1450是由管理员手工配置
D. 交换机重启后，所有MAC地址都需要重新学习
