【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
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相关试题
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
【单选题】
（1）地球表层覆盖着很多圈层，其中最厚的圈层是 ___
A. 岩石圈
B. 水圈
C. 大气圈
D. 生物圈
【单选题】
（2）目前受人类影响最强烈的地球圈层部位主要在大气圈底层、岩石圈上层以及 ___
A. 生物圈表层
B. 生物圈中层
C. 水圈底层
D. 水圈全部
推荐试题
【单选题】
灰浆泵泵送的灰浆的稠度为___mm。
A. 60~80
B. 70~80
C. 80~120
D. 120~140
【单选题】
扣件式钢管脚手架所用的钢管规格尺寸___。
A. Φ48x3.5或Φ51x3
B. Φ38x2.5
C. Φ30x1.5
D. Φ62x4
【单选题】
横向水平杆(小横杆)的最大长度应为___。
A. 3500mm
B. 4000mm
C. 2200mm
D. 5000mm
【单选题】
纵向水平杆(大横杆)的最大长度应为___。
A. 6500mm
B. 5000mm
C. 4500mm
D. 4000mm
【单选题】
扣件式钢管脚手架所用的扣件应采用___。
A. 钢板压制扣件
B. 可锻铸铁制作的扣件
C. 材质符合《钢管脚手架扣件》规定的可锻铸铁制作的扣件
D. 其他形式扣件
【单选题】
在脚手架主节点处必须设置一根横向水平杆(小横杆)，用直角扣件扣紧，且严禁拆除，这是因为___。
A. 横向水平杆是构成脚手架整体刚度的必不可少的杆件
B. 横向水平杆是承传竖向荷载的重要受力构件
C. 横向水平杆是承传竖向、水平荷载的重要受力构件
D. 横向水平杆是承受竖向荷载的重要受力构件，又是保证脚手架的整体刚度的不可缺少的杆件
【单选题】
为计算简便，并确保安全，对脚手架立杆要求___。
A. 仅按轴心压杆计算
B. 仅按压弯杆计算
C. 仅按受弯杆计算
D. 既按轴心压杆又按压弯杆计算
【单选题】
计算纵向或横向水平杆与立杆的连接扣件抗滑承载力时，应采用扣件抗滑承载力的设计值，其值为___。
A. 10kN；
B. 3.2kN；
C. 8kN；
D. 40kN
【单选题】
纵向水平杆(大横杆)的内力和挠度按___。
A. 两端固接的单跨梁计算
B. 两跨连续梁计算
C. 三跨连续梁计算
D. 既可按单跨梁又可按三跨连续梁计算
【单选题】
已知双排架连墙件间距竖向为H1，，水平向为L1，风荷载标准值WK，则此脚手架连墙件所受水平力设计值为___。
A. H1×L1×WK＋3kN
B. 1.4H1×L1×WK＋3kN
C. 1.4 H1×L1×WK＋5kN
D. H1×L1×WK＋5kN
【单选题】
当脚手板采用竹笆板时，纵向水平杆应满足以下要求___。
A. 等间距设置，最大间距不大于400mm
B. 等间距设置，最大间距不大于300mm
C. 等间距设置，最大间距不大于500mm
D. 间距不限
【单选题】
脚手架作业层上为支承脚手板在非主节点处设置横向水平杆的要求是___。
A. 宜等间距设置，最大间距不大于纵距的1／3
B. 宜等间距设置，最大间距不大于纵距的1/2
C. 宜等间距设置，最大间距不大于1000mm
D. 宜等间距设置，最大间距不大于750
【单选题】
单排脚手架的横向水平杆设置应满足要求___。
A. 一端用直角扣件固定在纵向水平杆上，另一端插入墙内，插入深度不小于180mm
B. 一端用旋转扣件固定在纵向水平杆上，另一端插入墙内，插入深度不小于100mm
C. 一端用旋转扣件固定在纵向水平杆上，另一端插入墙内，插入深度不小于80mm
D. 一端用直角扣件固定在纵向水平杆上，另一端插入墙内，插入深度不小于50mm
【单选题】
脚手架作业层的脚手板铺设规定为___。
A. 可以不满铺
B. 应满铺、铺稳
C. 应铺满、铺稳，离开墙面不超过120~150mm
D. 应铺满、铺稳，离开墙面200~300mm处可以不设任何防护
【单选题】
冲压钢脚手板对接平铺时，接头处构造应满足的要求是___。
A. 接头处必须设一根横向水平杆
B. 接头处必须设两根横向水平杆；脚手板外伸长度应取130~150mm；且两块脚手板外伸长度之和不大于300mm
C. 接头处必须设两根横向水平杆；两块脚手板外伸长度之和不大于400mm
D. 接头处必须设两根横向水平杆；两块脚手板外伸长度之和不大于300mm
【单选题】
脚手板搭接铺设时，接头必须支在横向水平杆上，搭接长度和伸出横向水平杆的长度应分别为___。
A. 大于200mm和不小于100mm
B. 大于80mm和不小于50mm
C. 大于40mm和不小于200mm
D. 大于100mm和不小于50mm
【单选题】
脚手架底层步距不应___。
A. 大于2m
B. 大于3m
C. 大于3.5m
D. 大于4.5m
【单选题】
有—双排脚手架，搭设高度为48m；步距h=1.5m跨距La= 1.8m，此脚手架连墙件布置除应满足计算要求外，其最大竖向间距和最大水平间距还应不大于___。
A. 竖向6m，水平向6m
B. 竖向5m，水平向5.4m
C. 竖向4.5m，水平向5.4m
D. 竖向4.5m，水平向6m
【单选题】
连墙件应靠近主节点设置，这是为了___。
A. 便于施工
B. 便于连墙件没置
C. 便于立杆接长
D. 保证连墙件对脚手架起到约束作用
【单选题】
连墙件设置要求是___
A. 应靠近主节点，偏离主节点的距离不应大于600mm
B. 应靠近主节点，偏离主节点的距离不应大于300mm
C. 应远离主节点，偏离主节点的距离不应小于400mm
D. 应远离主节点，偏离主节点的距离不应小于600mm
【单选题】
对一字形、开口形脚手架连墙件的设置规定___。
A. 是相同的
B. 要求较低
C. 无特别考虑
D. 更为严格，有专门规定
【单选题】
高度24m以上的双排脚手架连墙件构造规定为___。
A. 可以采用拉筋和顶撑配合的连墙件
B. 可以采用仅有拉筋的柔性连墙件
C. 可采用顶撑顶在建筑物上的连墙件
D. 必须采用刚性连墙件与建筑物可靠连接
【单选题】
连墙件必须___。
A. 采用可承受压力的构造
B. 采用可承受拉力的构造
C. 采用可承受压力和拉力的构造
D. 采用仅有拉筋或仅有顶撑的构造
【单选题】
剪刀撑的设置宽度___。
A. 不应小于4跨，且不应小于6m
B. 不应小于3跨，且不应小于4.5m
C. 不应小于3跨，且不应小于5m
D. 不应大于4跨，且不应大于6m
【单选题】
剪刀撑斜杆与地面的倾角宜___。
A. 在45°~75°之间
B. 在45°~60°之间
C. 在30°~60°之间
D. 在30°~75°之间
【单选题】
剪刀撑斜杆用旋转扣件固定在与其相交的横向水平杆伸出端或立杆上，旋转扣件中心线至主节点的距离不应___。
A. 大于150mm
B. 小于150mm
C. 大于300mm
D. 小于300mm
【单选题】
运料斜道的宽度和坡度的规定是___。
A. 不宜小于0.8m和宜采用1:6
B. 不宜小于1.5m和宜采用1:6
C. 不宜小于0.5m和宜采用1:3
D. 不宜小于1.5m和宜采用1:7
【单选题】
人行斜道的宽度和坡度的规定是___。
A. 不宜小于1m和宜采用1:8
B. 不宜小于0.8m和宜采用1:6
C. 不宜小于1m和宜采用1:3 C．不宜小于1.5m和宜采用l:7
【单选题】
双排脚手架横向水平杆靠墙一端至墙装饰面的距离不宜___。
A. 大于100mm
B. 大于600mm
C. 大于500mm
D. 大于400mm
【单选题】
脚手架立杆底座底面标高宜至少应高于自然地坪___。
A. 100mm
B. 70mm
C. 50mm
D. 30mm
【单选题】
立杆底座下的垫板长度和厚度尺寸是___。
A. 不宜小于3跨和小于50mm
B. 不宜小于2跨和小于50mm
C. 不宜小于2跨和小于30mm
D. 不宜小于3跨和小于30mm
【单选题】
脚手架施工荷载按均布荷载计算可分为___。
A. 承重架(结构施工用)3kN／m2，装修架2kN／m2
B. 承重架2.7kN／m2，装修架2.5kN／m2
C. 承重架2kN／m2，装修架1kN／m2
D. 承重架5kN／m2，装修架4kN／m2
【单选题】
当脚手架基础下有设备基础、管沟时，___。
A. 如果不采取加固措施，不应开挖
B. 可以开挖，否则施工进度跟不上
C. 可以开挖，不必采取加固措施
D. 开挖后，墓础可以暂时悬空
【单选题】
脚手架搭设时，应遵守：___。
A. 一次搭设高度不应超过相邻连墙件以上二步
B. 一次搭设高度可以不考虑连墙件的位置
C. 一次搭设高度可以在相邻连墙件以上四步
D. 一次搭设高度可以在相邻连墙件以上五步
【单选题】
开始搭设立杆时，应遵守下列规定：___。
A. 每隔6跨设置一根抛撑，直至连墙件安装稳定后，方可拆除
B. 搭设立杆时，可以不必设置抛撑和连墙件，一直搭到顶
C. ，采用钢丝和结构固定，待立杆搭设到顶后，再回过头来安装连墙件
D. 相邻立杆的对接扣件都可在同一个水平面内
【单选题】
纵向水平杆(大横杆)的对接扣件应符合下列规定：___。
A. 应交错布置，两根相邻杆的接头，在不同步或不同跨的水平方向错开的距离应不小于500mm，各接头中心距最近的主节点的距离不大于纵距的1／3
B. 两根相邻杆的接头，应在同一步和同一跨内布置
C. 两根相邻杆的接头，可在同一个竖向平面内
D. 两根相邻杆的接头，在水平方向的接头可在200mm以内
【单选题】
各类杆件端头伸出扣件盖板边缘的长度，应为___。
A. 100mm
B. 80mm
C. 50mm
D. 200mm
【单选题】
脚手架拆除时必须是___。
A. 必须由上而下逐层进行，严禁上下同时作业
B. 可以上下同时拆除
C. 由下部往上逐层拆除
D. 对于不需要的部分，可以随意拆除
【单选题】
当脚手架采取分段，分立面拆除时，对不拆除的脚手架___。
A. 应在两端按规定设置连墙件和横向斜撑加固
B. 可不设加固措施
C. 不必设连墙件
D. ，设置卸荷措施
【单选题】
扣件拧紧抽样检查的数目及质量制定标准为：___。
A. 连接横向水平杆与纵向水平杆的扣件，每51~90个应抽检5个，不允许存在不合格
B. 1000个扣件以内，不必抽检
C. 每抽查时，允许有30％不合格
D. 抽检时，可不用扭力矩扳手检查
