【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
查看试卷，进入试卷练习
微信扫一扫，开始刷题
相关试题
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
推荐试题
【单选题】
如果触电者伤势严重,呼吸停止或心脏停止跳动,应竭力施行___和胸外心脏按压。
【单选题】
乙炔瓶的定期检验,每三年进行一次,库存或停用周期超过___年的乙炔瓶,启用前应进行检验。
【单选题】
在不大于规定充装量的条件下,液化石油气储罐的压力随___变化而变化。
A. 储存温度
B. 充装量
C. 输送设备的压力
【单选题】
劳动者离开用人单位时,有权索取本人职业健康监护档案复印件,用人单位应当如实、无偿提供,并在所提供的复印件上___。
【单选题】
在炸药中掺入少量炭黑、石墨、硼粉等导电物质,以降低炸药的___,减少静电的积聚。
【单选题】
易燃品闪点在28℃以下,气温高于28℃时应当在___运输。
【单选题】
如果可燃气体在泄漏的同时被点燃,将会在泄漏处发生 ___。
【单选题】
根据《常用化学危险品贮存通则》规定,下列贮存方式不属于危险化学品贮存方式的是___贮存。
【单选题】
危险化学品存在的主要危险是___。
A. 火灾、爆炸、中毒、腐蚀及污染环境
B. 火灾、爆炸、中毒、灼伤及污染环境
C. 火灾、爆炸、感染、腐蚀及污染环境
【单选题】
我国包装代码标准与联合国标准基本相同,用___表示容器的种类。
【单选题】
国家标准《安全色》中规定,对比色使安全色更加醒目的反衬色,包括___两种颜色。
【单选题】
特种设备在投入使用前或者投入使用后___日内,特种设备使用单位应当向直辖市或者设区的市的特种设备安全监督管理部门登记。
【单选题】
压缩气体和液化气体必须与爆炸物品、氧化剂、易燃物品、自燃物品、腐蚀性物品___储存。
【单选题】
危险化学品经营单位经营方式发生变化的,应当___办理经营许可证。
【单选题】
根据《工伤保险条例》,职工在工作时间和工作场所内,因履行工作职责受到暴力等意外伤害,但本人醉酒的,___认定为工伤。
【单选题】
化学品使用单位,应向___索取全套的最新的化学品安全技术说明书。
A. 安全生产许可证发证机关
B. 生产商
C. 供应商
【单选题】
安全检查是指对生产过程及安全管理中可能存在的事故隐患、危险与有害因素、安全缺陷等进行___。
【单选题】
企业应根椐重大危险源目标模拟事故___,制订出各种状态的应急处置方案。
【单选题】
应急救援过程中,救援人员在做好自身防护的基础上,应快速___,控制事故发展。
【单选题】
事故隐患分为一般事故隐患和___事故隐患。
【单选题】
没有建立专职应急救援队的危险化学品企业必须与邻近的具备相应能力的专业救援队签订应急___。
【单选题】
危险化学品单位应当将其危险化学品事故应急预案报所在地设区的___级人民政府安全生产监督管理部门备案。
【单选题】
《危险化学品安全管理条例》规定,国家对危险化学品经营实行___制度。
【单选题】
《危险化学品安全管理条例》规定,危险化学品单位的___对本单位的危险化学品安全管理工作全面负责。
A. 主要负责人
B. 安全管理人员
C. 安全负责人
【单选题】
屏护装置把___同外界隔离开来,防止人体触及或接近。
【单选题】
《气瓶安全监察规程》规定,车用液化石油气钢瓶,每___年检验一次。
【单选题】
《气瓶安全监察规程》规定,气瓶充装登记有效期为___年。
【单选题】
在生产过程、劳动过程、___环境中存在的危害劳动者健康的因素,称为职业性危害因素。
【单选题】
一般来讲___。
A. 液体比较容易燃烧,其次是气体,再次是固体
B. 气体比较容易燃烧,其次是液体,再次是固体
C. 固体比较容易燃烧,其次是液体,再次是气体
【单选题】
常用危险化学品的标志设主标志和副标志,副标志___种。
【单选题】
在《常用危险化学品的分类及标志》中,自燃物品的安全标志是___。
【单选题】
易燃液体灌装时应控制流速,其流速不得超过3m/s,其原因是___。
【单选题】
贮存化学品的仓库有___要求。
A. 同时存放酸与碱
B. 不得同时存放酸与碱
C. 任意存放各类化学品
【单选题】
企业安全目标管理体系的建立是一个___过程,是全体职工努力的结果,是集中管理与民主相结合的结果。
A. 自下而上
B. 自上而下、自下而上反复进行
C. 各部门间横向反复
【单选题】
下列___对本岗位的安全生产负直接责任。
【单选题】
零售业务的店面内只许存放民用小包装的危险化学品,其存放总质量不得超过___t。
