【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
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相关试题
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
(2)Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
(7)Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
(3) As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site(s) of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
【单选题】
(1)地球表层覆盖着很多圈层,其中最厚的圈层是 ___
A. 岩石圈
B. 水圈
C. 大气圈
D. 生物圈
【单选题】
(2)目前受人类影响最强烈的地球圈层部位主要在大气圈底层、岩石圈上层以及 ___
A. 生物圈表层
B. 生物圈中层
C. 水圈底层
D. 水圈全部
【单选题】
(3)生物圈的范围为___
A. 大气圈、水圈和岩石圈的全部
B. 大气圈和水圈的全部、岩石圈的上部
C. 大气圈的底部、水圈和岩石圈的全部
D. 大气圈的底部、水圈的全部和岩石圈的上部
【单选题】
(4)地球上最大的生态系统是 ___
A. 森林生态系统
B. 生物圈
C. 海洋生态系统
D. 城市生态系统
【单选题】
(5)被称为地球之“肺”的是:___
A. 草原
B. 针叶林
C. 沼泽地
D. 热带雨林
推荐试题
【单选题】
对于昏睡与昏迷的鉴别,最有价值的是___
A. 瞳孔对光反应正常否
B. 角膜反射存在与否
C. 膝腱反射是否消失
D. 能否看到吞咽动作
E. 患者能否被唤醒
【单选题】
抢救急性一氧化碳中毒的关键是及时纠正脑缺氧,最有效的措施是___
A. 高压氧舱吸氧
B. 使用呼吸兴奋剂
C. 采用人工呼吸器
D. 输新鲜血或换血疗法
E. 解除脑血管痉挛,静脉滴注1g/L普鲁卡因
【单选题】
正常足月妊娠时,羊水量约为___
A. 350ml
B. 500ml
C. 1000ml
D. 2000ml
E. 250ml
【单选题】
下列哪类药物服用后须多饮水___
A. 铁剂
B. 止咳糖浆
C. 助消化药
D. 健胃药
E. 磺胺类药
【单选题】
下列情况中,不能通过心电图做出判断的是___
A. 心律失常
B. 心室肥大
C. 心肌损害
D. 心功能不全
E. 束支传导阻滞
【单选题】
某病人推之不醒、呼之不应。查体:瞳孔散大,角膜反射消失,可能为___
A. 熟睡
B. 嗜睡
C. 昏睡
D. 浅昏迷
E. 深昏迷
【单选题】
下列关于结核菌素试验结果描述正确的是___
A. 结核菌素试验阴性即可除外结核
B. 卡介苗接种成功,结核菌素反应多呈阳性
C. 重症肺结核的结核菌素反应阳性
D. 结核菌素试验阳性,肯定有结核病
E. 初次感染结核后4周内,结核菌素试验阳性
【单选题】
一健康小儿体重18kg,身长100Cm。其年龄约为___
A. 3岁
B. 4岁
C. 5岁
D. 6岁
E. 7岁
【单选题】
双气囊三腔管插入多长时间开始间断放气___
A. 6h
B. 12h
C. 24h
D. 36h
E. 48h
【单选题】
尿道损伤愈合后易引起___
A. 膀胱容量变小
B. 经常血尿
C. 膀胱炎
D. 尿道狭窄
E. 尿道炎
【单选题】
护理重度营养不良患儿,应特别注意观察可能发生下列哪种情况___
A. 重度贫血
B. 低血钠
C. 低血钾
D. 低血糖
E. 继发感染
【单选题】
中毒型痢疾多见于___
A. 新生儿
B. 婴幼儿
C. 儿童
D. 青年
E. 成人
【单选题】
对可疑糖尿病患者最有诊断价值的诊断检查是___
A. 尿糖定性试验
B. 尿糖定量测定
C. 空腹血糖测定
D. 口服葡萄糖耐量试验
E. 胰岛细胞抗体测定
【单选题】
早期妊娠快速准确的辅助检查为___
A. X线
B. B超检查
C. 妊娠试验
D. 黄体酮试验
E. 基础体温测定
【单选题】
用于冲洗外伤伤口以预防厌氧菌感染的外用药是___
A. 0.02%呋喃西林
B. 0.9%氯化钠
C. 0.01%新洁尔灭
D. 3%过氧化氢
E. 0.02%洗必泰
【单选题】
铺无菌盘时哪项是错误的___
A. 用无菌持物钳夹取治疗巾
B. 注意使治疗巾边缘对齐
C. 治疗巾开口部分及两侧反折
D. 有效期不超过6h
E. 避免潮湿和暴露过久
【单选题】
糖尿病诊断标准为___
A. 空腹血糖≥7.0mmol/L
B. 空腹血糖≥11.1mmol/L
C. 餐后血糖≥7.0mmol/
D. 餐后血糖≥7.8mmol/L
E. 空腹血糖≥6.0mmol/L
【单选题】
幼儿期是指___
A. 生后29天至1周岁
B. 1~3周岁
C. 2~5周岁
D. 3~5周岁
E. 4~6周岁
【单选题】
婴儿饮食中,三大营养素(蛋白质:脂肪:碳水化合物)所需热量的百分比正确的是___
A. 15:50:35
B. 15:35:50
C. 25:40:35
D. 25:35:40
E. 25:25:50
【单选题】
刺激性呛咳或带金属音的咳嗽应首先考虑___
A. 上呼吸道感染
B. 肺部病变早期
C. 左心功能不全
D. 支气管扩张
E. 支气管肺癌
【单选题】
现代医学模式为___
A. 生物一社会医学模式
B. 生物一心理医学模式
C. 生物一生理医学模式
D. 生物一生理一社会医学模式
E. 生物一心理一社会医学模式
【单选题】
儿科护理工作的中心是___
A. 儿童及其家庭
B. 病儿
C. 疾病
D. 病儿及其家属
E. 儿童预防保健
【单选题】
关于子宫肌瘤的正确说法是___
A. 是妇科最常见的恶性肿瘤
B. 多发生于绝经期妇女
C. 肌壁间肌瘤少见
D. 黏膜下肌瘤多见
E. 黏膜下肌瘤易发生月经过多
【单选题】
自我照顾模式是由谁提出的___
A. 纽曼
B. 佩普劳
C. 汉斯席尔
D. 马斯洛
E. 奥瑞姆
【单选题】
预防阵发性夜间呼吸困难发作,最主要的护理措施是___
A. 保持安静,减少声、光的刺激
B. 夜间持续吸氧
C. 夜间睡眠应保持半卧位
D. 睡前给少量镇静剂
E. 注意保暖
【单选题】
新生儿颅内出血的诊断依据应除外___
A. 缺氧史
B. 尖叫
C. 产伤史
D. 嗜睡、拒乳
E. 感染病灶
【单选题】
斜疝修补术后,预防阴囊血肿的措施是___
A. 平卧位,膝下垫软枕
B. 预防便秘、尿潴留
C. 切口处用沙袋压迫并托起阴囊
D. 咳嗽时用手按压伤口
E. 不宜过早下床活动
【单选题】
小儿受结核菌感染致PPD试验阳性的时间为___
A. 2~4周
B. 4~8周
C. 8~10周
D. 10~12周
E. 12~16周
【单选题】
慢性胃炎临床表现一般不包括___
A. 食欲不振
B. 餐后腹胀
C. 恶心、呕吐
D. 反酸、嗳气
E. 规律性上腹痛
【单选题】
有关新生儿窒息。下述哪项正确___
A. 胎儿只有心跳无呼吸称新生儿窒息
B. 产时使用麻醉剂不可能造成新生儿窒息
C. 青紫窒息为重度窒息
D. 苍白窒息为轻度窒息
E. 苍白窒息时,全身皮肤苍白,仅口唇呈暗紫色
【单选题】
骑跨伤易引起尿道损伤的部位是___
A. 尿道口
B. 尿道球部
C. 尿道膜部
D. 前列腺部
E. 尿道中段
【单选题】
为病人保暧解痉最简便的方法是___
A. 热水袋
B. 热坐浴
C. 热湿敷
D. 温水浴
E. 红外线照射
【单选题】
婴儿手足搐搦症主要死亡原因是___
A. 无热惊厥
B. 心力衰竭
C. 喉痉挛
D. 呼吸衰竭
E. 手足搐搦
【单选题】
风湿性心脏病心房颤动病人突然抽搐、偏瘫。首先考虑___
A. 心力衰竭加重
B. 洋地黄中毒
C. 低钾血症
D. 脑栓塞
E. 蛛网膜下腔出血
【单选题】
外敷疖肿用___
A. 0.02%呋喃西林溶液
B. 0.1%雷佛奴尔溶液
C. 氧化锌软膏
D. 10%鱼石脂软膏
E. 0.75%碘伏
【单选题】
对一位需住院的心力衰竭病人,住院处的护理人员首先应___
A. 卫生处置
B. 介绍医院的规章制度
C. 立即护送病人人病区
D. 通知医生作术前准备
E. 了解病人有何护理问题
【单选题】
一个肾病综合征患儿,有胸腔积液,全身水肿较重,护理该患儿时不应采用的方法是___
A. 避免皮肤擦伤及受压
B. 保持皮肤清洁干燥
C. 阴囊部用吊带托起
D. 让患儿卧于橡胶单上以利清理床单位
E. 静脉穿刺时选好血管,争取一次穿刺成功
【单选题】
新生儿败血症出生后感染的主要途径是___
A. 口腔黏膜
B. 呼吸道
C. 脐部和皮肤
D. 泌尿道
E. 消化道
【单选题】
阑尾周围脓肿消退后作阑尾切除的最佳时间是___
A. 立即手术切除
B. 两周后手术切除
C. 3个月后手术切除
D. 数年后手术切除
E. 无须手术切除
【单选题】
糖尿病酮症酸中毒患者经注射胰岛素及静滴生理盐水后。血糖降低、失水纠正、尿量增多。此时最应注意防止___
A. 低钠血症
B. 低钾血症
C. 低钙血症
D. 低血糖
E. 低血压