【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
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相关试题
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
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【多选题】
NB-IoT系统无线帧长为（ ）。
A. 10ms
B. 5ms
C. 40ms
D. 20ms
【多选题】
NPDCCH信道的作用有（ ）。
A. 资源分配
B. 指示NPDSCH，NPUSCH的传输格式
C. 传递接入限制信息
D. 传递系统帧号
【多选题】
NB-IoT具有较低的传输速率，单用户下行速率峰值为（ ）。
A. 21.26kbps
B. 21.25kbps
C. 21.28kbps
D. 21.27kbps
【多选题】
NB–IoT上行子载波带宽有哪几种选择？（ ）
A. 7.5KHz
B. 3.75KHz
C. 180 KHz
D. 15KHz
【多选题】
OFDM numerology是OFDM系统的基础参数集合，包含（ ）。
A. 循环前缀长度
B. 子载波间隔
C. 系统带宽
D. TTI长度
【多选题】
下列选项中关于beam report描述有误的是：（ ）
A. UE通过RRC信令上报beam测量结果
B. 网络配置CSI-RS资源和上报方式
C. UE可以通过SSB进行beam测量上报
D. 可以将beam分组，以组的形式上报
【多选题】
对于1个服务小区，基站可以通过专用RRC信令给UE配置多个DL BWP和多个UL BWP，最多各配（ ）个。
【多选题】
5G中PUSCH支持的波形包括（ ）。
A. CP-OFDM
B. DFT-S-OFDM
C. S-OFDM
D. DFT-OFDM
【多选题】
SCG failure 后，下面正确的是（ ）。
A. 安全模式已建立情况下，回IDLE
B. 安全模式已建立情况下，启动重建流程
C. 不重建，触发SCG failure后，向MCG上报SCGFailureInformationNRmessage
D. 安全模式未建立情况下，启动重建流程
【多选题】
CDMA手机是通过接收（ ）信道消息来获得长码状态,系统时间等消息。
【多选题】
在CDMA 信道中每一帧的帧长是（ ）。
A. 40ms
B. 20ms
C. 100ms
D. 80ms
【多选题】
CDMA系统是自干扰系统,在前向链路主要是( )受限。
【多选题】
CDMA手机是通过接收（ ）信道消息来获得长码状态，系统时间等消息的？
【多选题】
40W功率折算到 dB域为（ ） dBm。
【多选题】
考虑到干扰控制，市区水平波束宽度一般不宜大于（ ）。
A. 120°
B. 65°
C. 360°
D. 90°
【多选题】
直放站中的关键技术有（ ）。
A. 增益，功率控制技术
B. 低噪放电路技术
C. 收发双工技术
D. RAKE接收技术
【多选题】
云端的虚拟基站集群构成虚拟网络，利用（ ）技术优化网络结构。
A. MAC
B. SDN
C. PHY
D. RLC
【多选题】
邻区比服务小区质量高于一个绝（相对）对门限，用于频内/ 频间基于覆盖的切换是基于（ ）事件的切换 。
【多选题】
用户反映上网速率慢时，常用的排查手段有哪些？( )
A. 信令，数据跟踪
B. ping
C. 模拟服务器测试
D. 镜像抓包
【多选题】
关于UMTS接入的QOS中，描述正确的是
A. P-CSCF将动态的QOS相关的应用层参数映射为决策建立信息
B. PDF实现IP承载层基于业务的本地策略控制
C. P-CSCF通过Go接口把决策建立信息传递给PDF
D. P-CSCF完成应用功能SF
【多选题】
单站点测试空闲模式需要验证的工作有哪些？（ ）
A. CINR检查
B. 频率检查
C. RSRP检查
D. PCI检查
【多选题】
NB-IoT上下行分别采用的多址技术分别是什么？（ ）
A. SCFDMA\SCFDMA
B. OFDMA\SCFDMA
C. OFDMA\OFDMA
D. SCFDMA\OFDMA
【多选题】
在NB-IoT技术中，R13版本采用的双工方式是（ ）。
A. FDD全双工
B. TDD
C. TDD半双工
D. FDD半双工
【多选题】
NB-IoT覆盖广，较2/3/4G网络覆盖更强，其增益为（ ）dB。
【多选题】
目前部署在授权的频段上的主要的物联网技术有（ ）。
A. LoRa
B. SIGFOX
C. NB-IoT
D. LTE-M
【多选题】
NB-IOT支持的下行物理信道有（ ）。
A. NPSS
B. NPDSCH
C. NPBCH
D. NPDCCH
【多选题】
Initial UL/DL BWP，Additional UL/DL BWP，SUL BWP均由哪三部分配置组成?（ ）
A. bwp-Dedicated
B. bwp-id
C. bwp-Uplink？
D. bwp-Common
【多选题】
NR中SR在下列哪个信道上发送？（ ）
A. PUSCH
B. PUCCH format1/format 0
C. PUCCH format3
D. PUCCH format1/1a/1b
【多选题】
对于NR中的上行SPS，下列说法错误的是（ ）。
A. Configured grant Type2配置之后，还需要通过CS-RNTI PDCCH激活才能使用
B. 通过ConfiguredGrantConfig来配置
C. ？Periodicity依据不同的子载波间隔取值范围不同
D. Configured grant Type1配置之后，还需要通过CS-RNTI PDCCH激活才能使用
【多选题】
下列选项中哪个不是在UCI上传递的信息（ ）。
A. SR
B. CSI
C. HARQ
D. DM-RS
【多选题】
下面哪个不是NR支持的PRG?（ ）
A. 8
B. 2
C. Wideband
D. 4
【多选题】
CDMA2000 1x系统前向信道包括哪些？（ ）
A. 同步信道
B. 导频信道
C. 寻呼信道
D. 接入信道
【多选题】
CDMA2000 1X采用的语音编码技术是（ ）。
A. 8K QCLEP
B. 8K EVRC
C. 13K QCLEP
D. 13K EVRC
【多选题】
下列哪些是属于前向信道？（ ）
A. Paging Channel
B. Access Channel
C. Broadcast Channel
D. Sync Channel
【多选题】
NFV网络功能虚拟化基础建设（NFVI），主要包含：（ ）三个功能区块。
A. 虚拟资源
B. 编排器
C. 虚拟化层
D. 硬件资源
【多选题】
NFV网络功能虚拟化基础建设（NFVI），主要包含哪三个功能区块？（ ）
A. 虚拟资源
B. 编排器
C. 虚拟化层
D. 硬件资源
【多选题】
对于选频直放站的频点改变是由 （ ）操作。
A. 本地终端设置
B. 自动随施主信号频率变化而变化
C. 基站
【多选题】
多普勒频移和哪些因素有关（ ）。
A. 速度
B. 频率
C. 路径损耗
D. 天线高度
【多选题】
单站点验证测试处于哪个网络优化流程之后。（ ）
A. RF优化
B. 项目准备和启动
C. 参数优化
D. 项目签约
【多选题】
同频小区重选参数cellReselectionPriority通过哪条系统消息广播？（ ）
A. 系统消息3
B. 系统消息1
C. 系统消息5
D. 系统消息2
