【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
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相关试题
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
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【单选题】
各种业务印章使用人员临时离开岗位时，应将业务印章和个人名章___
A. 随身携带
B. 交与内勤主任临时保管
C. 他人代管
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办理带磁条的一本(卡)通存折支取业务，账(卡)号必须由___读入。
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错款的处理：___按规定的手续审批后，长款归公，短款报损，不得以长补短。
A. 技术性错款
B. 责任事故性错款
C. 原封新币发生错款
D. 现金调拨发生的错款
【单选题】
错款的处理：___按规定的手续审批后，长款归公，短款自赔，不得以长补短。
A. 技术性错款
B. 责任事故性错款
C. 原封新币发生错款
D. 现金调拨发生的错款
【单选题】
___是鉴别人民币真假和进行反假币斗争的重要资料，县联社要指定专人负责并进行领发保管手续。
A. 真人民币
B. 假人民币
C. 人民币票样
D. 证券
【单选题】
___是做好现金收付和整点工作的基础和前提。
【单选题】
点钞的基本环节正确的顺序是___
A. 拆把持钞、清点、墩齐、扎把、记数、盖章
B. 拆把持钞、墩齐、记数、清点、扎把、盖章
C. 拆把持钞、清点、记数、墩齐、扎把、盖章
D. 拆把持钞、墩齐、清点、记数、扎把、盖章
【单选题】
下面不属于现金出纳工作的基本制度___。
A. 坚持钱账分管，当日核对帐款，“四双”制度
B. 坚持复核制度
C. 坚持交接手续和查库制度
D. 长款归公，短款报损制度
【单选题】
点钞的基本要领不包括___
A. 肌肉要放松、钞券要墩齐
B. 开扇要均匀、手指接触面要小
C. 盖章清晰
D. 动作要连贯、点数要协调
【单选题】
下列不符合可予兑换的残缺人民币的是___。
A. 在流通的过程中摩擦受到损伤的硬币，只要能辨别出正面的国徽或背面的数字的硬币
B. 对于票面污损、熏焦、水湿、油浸的票面残币少于二分之一的人民币
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D. 票面残缺三分之一，其余部分能照原样连接的人民币
【单选题】
票面残缺六分之一，其余部分能照原样连接的人民币可照___兑换。
A. 全额
B. 半数
C. 不予
D. 六分之五数
【单选题】
票面残缺三分之一，其余部分能照原样连接的人民币可照___兑换。
A. 全额
B. 半数
C. 不予
D. 三分之二数
【单选题】
对于票面污损、熏焦、水湿、油浸的票面残币少于五分之一的人民币可照___兑换。
A. 全额
B. 半数
C. 不予
D. 五分之四数
【单选题】
两张同版的百元人民币各取二分之一拼凑而成可___兑换。
【单选题】
定活两便储蓄存款存期满一年或超过一年时，计息应按一年期整存整取利率___计算。
A. 打六折
B. 打七折
C. 打七五折
D. 全额
【单选题】
下列证件可作为储蓄存款实名证件使用的是___
A. 学生证
B. 机动车驾驶证
C. 身份证复印件
D. 护照
【单选题】
可作为质押物的凭证有___
A. 整存整取定期储蓄存单
B. 活期储蓄存折
C. 零存整取定期储蓄存折
D. 股金证
【单选题】
活期储蓄存款结息日为___
A. 每季末月20日
B. 6月30日
C. 7月1日
D. 每季末月月底
【单选题】
一日一次性超过（ ）元以上的现金支付或一日数次累计超过（ ）元以上的现金支付，金融机构内部要逐笔登记。___
A. 3万 5万
B. 5万 5万
C. 3万 5万
D. 5万 10万
【单选题】
村镇银行会计科目划分为___科目。
A. 现金和转账
B. 表内和表外
C. 基本和特定
D. 原始和记账
【单选题】
票据上的金额可以由___授权补记。
A. 持票人
B. 出票人
C. 持票人或出票人
D. 以上答案均不对
【单选题】
5万元（含）以上的销户，若代理人代理销户时，必须提供___的身份证件。
A. 存款人
B. 代理人
C. 存款人和代理人
D. 均不需要
【单选题】
储户凭未到期的定期储蓄存款存单到___办理部分提前支取手续。
A. 本网点
B. 任一联网网点
C. 辖属内网点
D. 玉川村镇银行所属网点
【单选题】
点钞法的优点是持票人所占的票面较小，视线可及票面的四分之三，容易发现假币，挑剔残破币也较容易___。
A. 手持式单指单张
B. 手持式一指多张
C. 手持式四指拨动
D. 手持式五指拨动
【单选题】
___点钞法不易发现残破币和假币。
A. 手持式单指单张
B. 手持式一指多张
C. 手持式四指拨动
D. 手持式五指拨动
【单选题】
各种储蓄存款利率由人民银行制订，按___利率挂牌公告。
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会计资料必须做到合法、真实、准确___
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我国支付结算制度是以 ___ 为主体的。
A. “三票一卡”
B. 汇兑方式
C. 托收承付方式
D. 委托收款方式
【单选题】
会计凭证的处理指从 ___ 开始，经过审查和传递，到 为止的全过程。
A. 申领凭证、使用凭证
B. 填制凭证、保管凭证
C. 受理或填制凭证、装订保管
D. 装订保管、受理凭证
【单选题】
村镇银行的支行是 ___ 。
A. 法人机构
B. 非法人机构
C. 独立核算机构
D. 综合机构
【单选题】
存折存款是指 ___ 。
A. 活期存款
B. 储蓄存款
C. 定期存款
D. 担保存款
【单选题】
甲某2012年3月1日存入1000元，原定存期1年，假设存入时该档次存款月利率为千分之9，甲于2012年12月1日支取该笔存款，如果支取日挂牌公告的活期储蓄存款利率为千分之3，应付利息为 ___ 。
A. 81元
B. 54元
C. 27元
D. 17元
【单选题】
存款实名制自什么时间施行: ___
A. 2000年4月1日
B. 2000年5月1日
C. 2001年4月1日
D. 2000年7月1日
【单选题】
关于支付结算应遵循的原则中不含：___
A. 诚实
B. 谁的钱进谁的帐，归谁支配
C. 银行不垫款
D. 银行负责强制扣款
【单选题】
会计档案保管期限分为 ___ 和 两种。
A. 永久、长期
B. 永久、定期
C. 短期、永久
D. 短期、长期
【单选题】
假币收缴单位应当自收到鉴定单位通知之日起 ___个工作日内，将需要鉴定的货币送达鉴定单位。
【单选题】
存款人的工资、奖金等现金的支取只能通过哪个账户___支取。
A. 一般存款账户
B. 临时存款账户
C. 专用存款账户
D. 基本存款账户
