【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
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【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3)The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
(2)Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
(7)Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
(3) As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site(s) of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
推荐试题
【单选题】
与市场风险和信用风险相比,商业银行的操作风险具有___。
A. 特殊性.非盈利性和可转化性
B. 普遍性.非盈利性和可转化性
C. 特殊性.盈利性和不可转化性
D. 普遍性.盈利性和不可转化性
【单选题】
商业银行的信贷业务不应集中于同一业务.同一性质甚至同一国家的借款者,应是多方面开展,这里基于___的风险管理策略。
A. 风险对冲
B. 风险分散
C. 风险转移
D. 风险补偿
【单选题】
风险识别方法中常用的情景分析法是指___。
A. 将可能面临的风险逐一列出,并根据不同的标准进行分类
B. 通过图解来识别和分析风险损失发生前存在的各种不恰当行为,由此判断和总结哪些失误最可能导致风险损失
C. 通过有关数据.曲线.图表等模拟商业银行未来发展的可能状态,识别潜在的风险因素.预测风险的范围及结果,并选择最佳的风险管理方案
D. 风险管理人员通过实际调查研究以及对商业银行的资产负债表.损益表.财产目录等财务资料进行分析从而发现潜在风险
【单选题】
风险因素与风险管理复杂程度的关系是___。
A. 风险因素考虑得越充分,风险管理就越容易
B. 风险因素越多,风险管理就越复杂,难度就越大
C. 风险因素的多少同风险管理的复杂性的相关程度并不大
D. 风险管理流程越复杂,则会有效减少风险因素
【单选题】
以下哪一个模型是针对市场风险的计量模型?___
A. CreditMetrics
B. KMV模型
C. VaR模型
D. 高级计量法
【单选题】
预期损失率的计算公式是___。
A. 预期损失率=预期损失/资产风险敞口
B. 预期损失率=预期损失/贷款资产总额
C. 预期损失率=预期损失/风险资产总额
D. 预期损失率=预期损失/资产总额
【单选题】
信用风险经济资本是指___。
A. 商业银行在一定的置信水平下,为了应对未来一定期限内信用风险资产的非预期损失而应该持有的资本金
B. 商业银行在一定的置信水平下,为了应对未来一定期限内信用风险资产的预期损失而应该持有的资本金
C. 商业银行在一定的置信水平下,为了应对未来一定期限内信用风险资产的非预期损失和预期损失而应该持有的资本金
D. 以上都不对
【单选题】
情景分析用于___。
A. 测试单个风险因素或一小组密切相关的风险因素的假定运动对组合价值的影响
B. 一组风险因素的多种情景对组合价值的影响
C. 着重分析特定风险因素对组合或业务单元的影响
D. A和C
【单选题】
资产证券化的作用在于___。
A. 提高商业银行资产的流动性
B. 增强商业银行关于资产和负债管理的自主性
C. 是一种风险转移的风险管理方法
D. 以上都正确
【单选题】
在贷款定价中,RAROC是根据哪个公式计算出来的?___。
A. RAROC=贷款年收入/监管或经济资本
B. RAROC=(贷款年收入-预期损失)/监管或经济资本
C. RAROC=(贷款年收入-各项费用-预期损失)/监管或经济资本
D. 以上都不对
【单选题】
在上题中,根据边际非预期损失占比,商业银行分配给关注类贷款的经济资本为___30×0.03/(0.02+0.03+0.05+0.1+0.1)=3
【单选题】
30.如果商业银行在当期为不良贷款拨备的一般准备是2亿,专项准备是3亿,特种准备是4亿,当期不良贷款为54亿,那么该商业银行当年的不良贷款拨备覆盖率是___。
A. 0.25
B. 0.14
C. 0.17
D. 0.3
【单选题】
1、治安保卫重点单位应当在公安机关指导下制定单位内部治安突发事件___,并定期演练。
【单选题】
各级保卫职能部门是消防安全___,负责与公安消防部门的协调和联系。
【单选题】
营业场所应当每___配备一只灭火器,最低不得少于2只。
A. 10方米
B. 15平方米
C. 20平方米
【单选题】
志愿消防队要定期开展消防业务训练,每年组织___灭火实战演。
【单选题】
《银行营业场所风险等级和防护级别的规定》(GA38-2004)中,将营业场所风险等级划分为___
【单选题】
营业场所风险等级和防护级别中,风险最高和防护要求最高的是___
【单选题】
营业场所周边防护不达标的是___
A. 无外围围墙
B. 有围墙,无防爬越障碍物
C. 既有围墙,又有周界报警器
D. 无围墙,有周界报警器
【单选题】
银行营业场所应安装金属防护栏的楼层要求是___
A. 二层(含二层)以下
B. 三层(含三层)以下
C. 四层(含四层)以下一步
D. 五层(含五层)以下
【单选题】
现金业务区应安装不少于()独立防区的紧急报警装置___
【单选题】
营业场所与外界相通的出入口安装的监控装置,必须达到的要求是___
A. 回放图像应能耐清晰分辩出入人员体貌特征
B. 回放图像应能清晰分辨人员面部特征
C. 回放图像应能清晰分辨出入人数
D. 回放图像应能清晰分辨出入人员手中所持之物
【单选题】
运钞交接区监控装置,必须要达到的要求是___
A. 回放图像应能清晰显示整个区域内人员活动情况
B. 回放图像应能能清晰分辨人员面部特征
C. 回放图像应能清晰分辨出体貌特征
D. 回放图像应能清晰分辨出入人员手中所持之物
【单选题】
自助设备、自助银行安装的针对操作人员的监控装置,必须达到的要求是___
A. 回放图像应能清晰分辩操作人员的体貌特征
B. 回放图像应能清晰分辨操作人员的面貌特征
C. 回放图像应能清晰分辨操作人员的活动情况
D. 回放图像应能清晰分辨操作人员的手中之物
【单选题】
自助设备、自助银行安装的监控装置,不可摄入的部位是___
A. 出纳加钞
B. 客户面部
C. 客户密码输入
D. 街面情况
【单选题】
业务库清点室安装的视频安防监控,应达到的效果是___
A. 对复点过程监控
B. 对打捆过程监控
C. 对装箱过程监控
D. 以上各项都是
【单选题】
自助设备、自助银行必须安装的设施有___
A. 震动报警装置
B. 报警联动装置
C. 监控装置
D. 以上都是
【单选题】
营业场所安排不少于___名工作人员接款箱,并随时做好报警工作。
【单选题】
营业人员确需离开柜台时,必须报告当班负责人同意,并将___等入箱加锁,退出业务系统应用程序,并妥善处理桌面有关物品,在确认安全情况下离开现金区。
A. 现金、印鉴、有价证券
B. 现金、重要凭证、印鉴
C. 现金、印鉴、密押、有价证券
D. 现金、印鉴、密押、重要凭证、有价证券
【单选题】
营业期间,遇到公安、银监部门和上级主管单位人员需进入现金业务区、监控室等场所检查时,除核对其介绍信、身份证或工作证等有效证件、做好登记外,还须___陪同方可进入。
A. 有临柜人员或一般工作人员
B. 有单位安全员
C. 有上一级主要领导
D. 有负责人或上级保卫职能部门负责人
【单选题】
农村合作金融系统安全保卫工作的原则是___。
A. 人人有责
B. 谁主管、谁负责
C. 分管领导负责
【单选题】
当营业场所遭遇不法分子侵犯时,其处置方式是___。
A. 先报警、再反击、后防身
B. 先藏身、后报警、再反击
C. 先反击、再防身、后报警
【单选题】
营业人员打开联动互锁门进入营业室前,应___。
A. 整理好工作服
B. 搞好大厅外的卫生
C. 与大厅外的客户招呼
D. 注意身边是否有人员尾随
【单选题】
营业人员下班办理交接工作,下列说法正确的是___。
A. 可由交班人员独自办理全部交接
B. 可由交班人员办理好有关交接工作后,由接班人员签字或输入柜员密码确认
C. 由交接班任何一方对交接内容及实物进行核对
D. 由交接双方对交接内容及实物进行核对,并有第三人进行监交。在未办好全部交接手续前,移交人员不得离开交接现场。
【单选题】
金库守库值班人员在守库值班岗位上严禁___。
A. 吃晚饭
B. 喝酒
C. 查看库区周边监控录像图像
D. 搞值班室卫生
【单选题】
对金库守库值班人员在守库值班期间的用枪规定,下列说法不正确的是___。
A. 守库值班人员使用枪支值班必须要先取得持枪证资格
B. 只有坐班制才允许使用枪支
C. 使用枪支守库值班时,枪支应装上子弹并上膛,打开保险
【单选题】
晚间金库值班期间,库区防入侵报警系统被触发,守库人员不应___。
A. 拿起自卫武器
B. 立即出去巡视
C. 通过电视监控设备观察
D. 守库人员互相联络
【单选题】
专职守库、押运人员遇到下列哪种情形不得向犯罪分子射击___。
A. 保卫目标受到暴力侵袭或者有受到暴力侵袭的紧迫危险,非开枪不能制止的
B. 佩带的武器遭到暴力抢夺,非开枪不能制止的
C. 遭到暴力侵袭,非开枪不能自卫的
D. 罪犯已慑服的
【单选题】
金库毗邻发生火灾时,守库人员应___。
A. 全部出去参加救火
B. 向119报警并(和)向单位领导报告
C. 马上转移库款
D. 人员全部转移
【单选题】
运钞车到达营业场所后,下列做法不对的是___。
A. 运钞车开进营业场所后院
B. 运钞车熄火
C. 运钞车停在电视监控的监控范围内
D. 武装押运人员下车