【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
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【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
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【单选题】
当APU火警按钮按出后，对电气有何影响？___
A. APU发电机不工作。
B. APU发电机脱开。
C. APU发电机工作。
D. 以上都不对
【单选题】
哪部显示会出现警告信息？___
A. 系统显示。
B. 发动机和警告显示。
C. 状态显示。
D. 以上都不对
【单选题】
在地面，双发关车，ECAM上通常会显示哪个系统的页面？___
A. 发动机页面。
B. 舱门/氧气页面
C. 电气页面。
D. 以上都不对
【单选题】
如果按压CALL（再现）电门，会出现什么情况？___
A. 警告受抑制。
B. 显示状态页面。
C. 警告再现。
D. 以上都不对
【单选题】
冲压空气开关何时使用？___
A. 任何时候
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C. 只在压差大于1SPI时
D. 只在放气valve完全打开时
【单选题】
电动刮雨器由两个独立的旋钮选择控制：___
【单选题】
风挡加温计算机为风挡提供两档加温功率：___
A. 高于20000英尺时为高功率，低于20000英尺时为低功率
B. 飞行中为高功率，地面为低功率
C. 结冰条件下为高功率，其他条件下为低功率
D. 以上都不对
【单选题】
刮雨器可以不同的速度工作：___
A. 低速和高速
B. 只有一个速度
C. 低速，中速，高速
D. 以上都不对
【单选题】
下列关于FIN号说法错误的是：___
A. FIN号的标签一般贴在设备附近
B. FIN号的标签一般贴在设备上
C. 每一个部件的Fin号是唯一的
D. 同一件号的件，Fin号可能不同
【单选题】
下面哪个表述是正确的:___
A. AMM/IPC/SRM/MMEL均为适航批准文件
B. FM/SB/SRM/MMEL均为适航批准文件.
C.
D.
【单选题】
___
A. AMM,IPC,SRM均为客户化手册
B. SM,ESPM均为通用手册
C.
D.
【单选题】
___
A. 可通过”TroubleShooting”功能找到排故程序
B. 应直接进入TSM查找排故程序.
C.
D.
【单选题】
在根据PFR上的ECAM和CFDS信息确定排故程序时:___
A. 所有的ECAM警告和CFDS故障信息均应分别处理查找各自相应的排故程序
B. 应依据”ATA”和”GMT”判断ECAM警告和CFDS故障信息的关联而进行综合分析
C.
D.
【单选题】
在排故程序中,Possiblecauses列出所有可能的故障原因:___
A. 它可以作为排故的捷径方法
B. 实际的故障原因还需要按排故程序的步骤确认
C.
D.
【单选题】
“2121-5012”是导线的:___
A. 识别号
B. 标准件号
C. 导线的规格号
D. 标准导线的件号
【单选题】
导线3231-0019的种类,直径,长度及相关插钉件号可以在那种手册中找到:___
【单选题】
___
A. “AWL-WirebyFINconnectorpin”
B. “AWL-Equipmentinformation”
C. AWM
D.
【单选题】
已知导线的识别号,如何查找导线的插钉件号:___
A. 通过菜单”AWM-Figurebywirenumber”
B. 通过菜单”AWL-Wireinformation”
C.
D.
【单选题】
___
A. 010件在某些飞机上禁止使用
B. 在”RU010”下面的件号只允许安装在”010”件上
C.
D.
【单选题】
下面哪个表述错误的是:___
A. LM表示航线可维护件
B. NP表示不可获得的件
C. D5323038320019是空客公司的产权件
D.
【单选题】
在IPC的件号有效性中,有时需要参考某一服务信涵SIL了解件号的互换性和混装性,而SIL如何查寻:___
A. 在EDCI(AirN@vEngineering)中
B. 在空客在线‘AOLS–TechnicalData–Engineeringtechnicaldocumentation’
C. 在AirN@vMaintenance中.
D. A和B均正确
【单选题】
航线发现某一液压接头有渗漏，如何查找紧固的标准力矩？___
A. MANINTENCE
B. ASSOCIATEDDATA
C. EDCI
D. 以上答案均不正确
【单选题】
___
A. SRMATA53章
B. AMMATA53章
C. CDLATA53章.
D.
【单选题】
机身外形整流罩丢失时,放行可能参考:___
【单选题】
如在AMM中要求使用消耗材料04-024,则:___
A. 只能使用与04-024对应的材料
B. 所有与04-024,04-024A,04-024B对应的材料均可使用.
C.
D.
【单选题】
在AirN@v手册中是否包含MPD？___
【单选题】
A320飞机可以选用哪种发动机？___
A. V2500A5或CFM56-5B
B. V2500A5或CFM56-3B
C. V2500D5或CFM56-5B
D. 以上都不对
【单选题】
A320飞机电子舱门有___
A. 2个
B. 3个
C. 4个
D. 以上都不对
【单选题】
A320飞机驾驶舱指示为灯灭逻辑___
【单选题】
A320飞机驾驶舱按钮上FAULT灯：___
A. 按钮在按下位时才有可能亮
B. 按钮在弹出位时灯亮
C. 只要有故障，该灯就亮，与按钮的位置无关
D. 不确定
【单选题】
A320系列飞机上的机头站位：___
A. 0
B. 100
C. 254
D. 2540
【单选题】
在新式A319飞机上，仪表显示器为：___
A. CRT
B. LCD
C. 等离子显示
D. 不确定
【单选题】
若通过姿态监控仪来检查飞机是否水平停放，则水滴应位于：___
【单选题】
在AMM手册中,关于勤务工作的页面块是___
A. 101-199
B. 201-299
C. 301-399
D. 401-499
【单选题】
要了解部件内更详细的信息,可参考:___
A. IPC
B. AMM
C. CMM
D. SRM
