【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
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【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
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【单选题】
零件长度为 36mm，切刀宽度为 4mm，左刀尖为刀位点，以右端面为原点，则编程时定位在___处切断工件。
A. Z-40
B. Z-36
C. Z-32
D. Z40
【单选题】
已知刀具沿一直线方向加工的起点坐标为（X20，Z-10），终点坐标为（X10，Z20），则其程序是___。
A. G01 X10 W30 F100
B. G01 X-10 Z20 F100
C. G01 X20 Z-10 F100
D. G01 U30 W-10 F100
【单选题】
程序段 G02 X50 Z-20 I28 K5 F0.3 中 I28 K5 表示___。
A. 圆弧的圆心相对圆弧起点坐标
B. 圆弧的终点C.圆弧的始点 D.圆弧的半径
【单选题】
暂停指令 G04 用于中断进给，中断时间的长短可以通过地址 X（U）或___来指定。
【单选题】
FANUC 系统指令 G50 S200 的含义是___。
A. 最高转速 200r/min
B. 最高线速度 200mm/min
【单选题】
下列关于基轴制的描述中，___是不正确的。
A. 基准轴的基本偏差为下偏差
B. 基轴制的轴是配合的基准件C.基准轴的上偏差数值为为零 D.基准孔下偏差为负值
【单选题】
限位开关在电路中起的作用是___。
A. 行程控制
B. 过载保护
C. 欠压保护
D. 短路保护
【单选题】
C.开环数控系统 D.开放式数控系统 11233.数控设备中，可加工最复杂零件的控制系统是___系统。
A. 轮廓控制
B. 点位控制
C. 直线控制
D. 以上都不是
【单选题】
滚珠丝杠螺母副消除间隙的目的是___。
A. 提高反向传动精度
B. 减小摩擦力矩
C. 增大驱动力矩
D. 提高使用寿命11236.采用双导程蜗杆传递运动是为了（ ）。
【单选题】
电机通过联轴器直接与丝杠联接，通常是电机轴与丝杠之间采用锥环无键联接或高精度十字联轴器联接，从而使进给传动系统具有较高的___和传动刚度，并大大简化了机械结构。
A. 传动精度
B. 运行速度
C. 传动位置
D. 传动频率
【单选题】
___不在每日检查范围之内。
A. 液压控制阀
B. 液压系统油标
C. 液压系统压力
D. 液压系统油温
【单选题】
数控机床进给传动方式有以下几种形式。其中___适用于负载力矩大、需要放大伺服电机输出扭矩的场合。
A. 电动机通过齿轮与丝杆连接
B. 电动机通过联轴器直接与丝杆连接C.电动机通过齿形带与丝杆连接 D.直线电动机直接驱动
【单选题】
以下___系统适用于大扭距切削。
A. 带有变速齿轮的主传动
B. 通过带传动的主传动C.由主轴电动机直接驱动的主传动 D.有电主轴的主传动
【单选题】
测量与反馈装置的作用是为了___。
A. 提高机床的定位精度、加工精度
B. 提高机床的使用寿命C.提高机床的安全性 D.提高机床的灵活性
【单选题】
数控机床的检测反馈装置的作用是：将其准确测得的___数据迅速反馈给数控装置， 以便与加工程序给定的指令值进行比较和处理。
A. 角位移或直线位移
B. 直线位移
C. 角位移
D. 直线位移和角位移
【单选题】
C.半闭环控制 D.半开环控制11244.在半闭环数控系统中，位置反馈量是___。
A. 进给伺服电机的转角
B. 机床的工作台位移
C. 主轴电机转速
D. 主轴电机转角
【单选题】
下列___检测元件检测线位移。
A. 感应同步器
B. 光电盘
C. 旋转变压器
D. 脉冲编码器
【单选题】
___属于成形类数控机床。
A. 数控冲床
B. 数控车床
C. 数控铣床
D. 数控激光切割机床11248.当 NC 故障排除后，按 RESET 键（ ）。
【单选题】
C.利用磁盘机读入程序 D.从网络通过 Modem 接收程序11250.数控机床加工调试中若遇到问题需停机，应先停止___。
A. 进给运动
B. 辅助运动
C. 主运动
D. 冷却液
【单选题】
请找出下列数控屏幕上菜单词汇的对应英文词汇 SPINDLE.EMERGENCY STOP 、FEED.、COOLANT ___。
A. 主轴、急停、进给、冷却液
B. 冷却液、主轴、急停、进给C.主轴、冷却液、急停、进给 D.进给、主轴、冷却液、急停
【单选题】
在机床执行自动方式下按进给暂停键，___会立即停止，一般在编程出错或将要碰撞时按此键。
A. 进给运动
B. 控制系统
C. 参数运算
D. 计算机
【单选题】
关于数控系统的串口通讯，错误的说法是___。
A. 如果数据传输不正常，可以通过拔下数据通讯线进行复位，然后再插上通讯线
B. 确认数控系统串口功能是否已开通
C. 确认上位机软件里的参数设置和数控系统里面的串口参数是否一样
D. 进行串口通讯前，首先检查传输线是否完好
【单选题】
在数控程序传输参数中，“9600E71”，分别代表___。
A. 波特率、奇偶校验、数据位、停止位
B. 数据位、停止位、波特率、奇偶校验C.波特率、数据位、停止位、奇偶校验D.数据位、奇偶校验、波特率、停止位
【单选题】
程序编制中首件试切的作用是___。
A. 检验程序单的正确性，并检查是否满足加工精度要求
B. 检验零件工艺方案的正确性
C. 检验零件图样的正确性
D. 检验数控程序的逻辑性
【单选题】
线切割机床加工模具时，可以加工___。
A. 以直线为母线的曲面
B. 任意空间曲面
C. 阶梯空
D. 不通孔
【单选题】
数控机床的位移量与指令脉冲数量___。
A. 成正比
B. 相等
C. 相反
D. 成反比
【单选题】
___。
A. 快速响应性能和运动精度
B. 运动精度和刚度
【单选题】
C.传动精度 D.传动精度和刚度11277.采用轮廓控制的数控机床是___。
【单选题】
在加工表面、刀具和切削用量中的切削速度和进给量都不变的情况下，所连续完成的那部分工艺过程称为___。
【单选题】
数控加工的批量生产中，当本道工序定位基准与上道工序已加工表面不重合时，就难以保证本道工序将要加工表面与上道工序已加工表面之间的___。
A. 位置精度
B. 表面质量
C. 尺寸精度
D. 形状精度
【单选题】
工艺尺寸链用于定位基准与___不重合时尺寸换算、工序尺寸计算及工序余量解算等。
A. 设计基准
B. 工艺基准
C. 装配基准
D. 工序基准
【单选题】
CAM 系统中的加工模拟无法检查___。
【单选题】
C.加工程序验证 D.优化加工过程11289.不完全定位是指___。
A. 根据工件的加工要求，有时并不需要限制工件的全部自由度。
B. 工件的六个自由度全部被限制的定位。一般当工件在 x、y、z 三个坐标方向上均有尺寸要求或位置精度要求时采用。
C. 根据工件的加工要求，应该限制的自由度没有完全被限制定位。此种定位无法保障加工要求，所以是绝对不允许的。
【单选题】
D.重复限制工件的同一个或几个自由度的现象。此种定位往往会带来不良后果，应尽量避免。11290.___适用凸模或较浅的型腔三维曲面工件的粗铣加工。
A. 等高层铣
B. 平行加工
C. 垂直插铣
D. 仿形加工
【单选题】
下列关于欠定位叙述正确的是___。
A. 应该限制的自由度没有限制完
B. 限制的自由度大于六个
C. 没有限制完六个自由度
D. 不该限制的自由度而限制了
【单选题】
工件以外圆柱面定位时，常用以下几种定位元件。其中___既能用于完整的圆柱面定位，也能用于局部的圆柱面定位，且对中性好。
A. V 形块
B. 定位套
C. 半圆套
D. 圆锥套
【单选题】
关于粗基准的选择和使用，以下叙述不正确的是___ 。
A. 当工件表面均需加工，应选加工余量最大的坯料表面作粗基准
B. 粗基准只能用一次
C. 选工件上不需加工的表面作粗基准
【单选题】
D.当工件所有表面都要加工，应选用加工余量最小的毛坯表面作粗基准11298.精基准是用___作为定位基准面。
A. 加工后的表面
B. 复杂表面
C. 切削量小的
D. 未加工表面
【单选题】
___在一定的范围内无需调整或稍加调整就可用于装夹不同的工件。这类夹具通常作 为机床附件由专业厂生产，操作费时、生产率低，主要用于单件小批量生产。
A. 通用夹具
B. 专用夹具
C. 可调夹具
D. 组合夹具
【单选题】
经常作为智能控制典型研究对象的是___。
A. 智能机器人
B. 智能故障诊断系统
C. 智能制造系统
D. 智能决策系统
