【单选题】
(5)Whicl of the following is a physiological process with negative feedback?___
A. blood coagulation
B. process of passing urine
C. sino-aortic baroreceptor reflex
D. process of parturition
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【单选题】
(6)Which of the following is not the characteristic of regulation by hormone?___
A. diffusenin nature
B. longer in duration
C. accurate in action
D. action in overcorrection
【单选题】
7)Which of the following is not the characteristic of cells?___
A. They are bound by the plasma membrane
B. They have the ability to break down large molecules to smaller ones to Liberate energy for their activities
C. They possess a nucleus which contains genetic information in the form of deoxyribonucleicacid(DNA).
D. Living cells can not transform materials.
【单选题】
8)The breakdown of large molecules to smaller ones is called___
A. respiration
B. anabolism
C. catabolism
D. absorption
【单选题】
9) Which of the following descriptions about the characteristics of nervous regulation is wrong?___
A. It responds fast
B. It acts exactly
C. It responds slowly.D.
D. uration is short
【单选题】
10)Which of the following descriptions about the control of body function is wrong?___
A. Homeostasis is kept by feedback control.
B. Negative feedback minimizes the changes, leading to stability.
C. Positive feedback is not useful.
D. Feed-forward makes human body foresee and adapt itself to the environment promptly.
【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
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【单选题】
已知圆的标准方程(x-3)2+(y-1)2=16,则该圆的半径r=___
【单选题】
已知圆的一般方程为x2+y2-16=0，则该圆的半径是___
【单选题】
斜率为2，在y轴上的截距是3的直线方程是___
A. 2x－y＋3＝0
B. 2x＋y＋3＝0
C. 2x－y－3＝0
【单选题】
直线的方程为y＝3x－5,则直线在y轴上的截距是___
【单选题】
下列点不在直线x＋y－2＝0上的是___
A. (0, 2)
B. (2, 0)
C. (1, 1)
D. (2, 2)
【单选题】
已知点A（1，2），点B（－1，4），则线段AB的中点坐标是___
A. （0，3）
B. （1，3）
C.
D. （0，6）
【单选题】
已知点O（0，0），点N（4，2），则线段ON的中点坐标是___
A. （2，1）
B. （1，2 ）
C. （0，2）
D. （0，-2）
【单选题】
关于零向量下列说法错误的是___
A. 零向量没有方向
B. 零向量的长度为0
C. 零向量与任一向量平行
D. 零向量的方向是任意的
【单选题】
直线2x－y＋5＝0的法向量是___
A. （2，-1）
B. （1，2 ）
C. （2，1）
D. （-1, 2）
【单选题】
直线方程y-3=x-1，它的截距是 ___
【单选题】
点A（－1，1）和B（3，4）之间的距离是___
【填空题】
2.直线x-y-1=0和x+y-3=0的交点是 《___ 》
【填空题】
1.直线mx+2y+1=0与x+2y+1=0互相垂直，求m= ___
【填空题】
2.直线x-y-1=0和x+y-3=0的交点是 ___ )
【单选题】
1．造成柴油机工作粗暴，发生敲缸的原因，是由于喷油提前角___造成的。
【单选题】
2．机车上自动开关(DZ)的作用是：___。
A. 防止电压过高
B. 自动保护和开关作用
C. 接通电路
【单选题】
3．JZ-7型空气制动机非操纵端自阀手把误放运转位时，当操纵端自阀施行制动时，操纵端中继阀排风口___。
【单选题】
4．JZ-7型空气制动机工作风缸充气止回阀胶垫不平整，阀口有损伤，有异物时，将工作风缸压力空气漏入___为内漏。
【单选题】
5．JZ-7型空气制动机客货车转换阀置于货车位，自阀手把制动区．过减位，取柄位 制动管都不能保压时，为___泄漏。
【单选题】
6．JZ-7空气制动机常用限压阀是当常用制动时，限制作用风缸压力不超过___。
A. 300kPa
B. 350kPa
C. 420kPa
【单选题】
7．JZ-7型空气制动机自阀制动后，工作风缸压力正常，机车制动缸压力逐渐增高，为___泄漏。
【单选题】
8．JZ-7型空气制动机客货车转换阀置于货车位，制动后保压良好，但降压快，自阀手把前2位增压缓慢时，为___及管路泄漏。
【单选题】
9．JZ-7型空气制动机使用自阀操纵，机车制动、缓解不良，但使用单阀操纵正常时，为___故障。
【单选题】
10．JZ-7型空气制动机单阀调整阀供气或排气部分泄漏，均会使阀盖下方缺口___。
【单选题】
11．机油系统对柴油机各运动部件进行___。
【单选题】
12．下列哪个部件属于高温水冷却部件。___
【单选题】
13．列车制动机为一次缓解型，JZ-7型空气制动机客货车转换阀手柄置于客车位时，当制动管有漏泄，或自阀置于常用制动区后误将手把在制动区向左移动时，会使列车制动机发生___。
【单选题】
14．JZ-7型空气制动机自阀制动，机车制动缸压力不能按比例上升，且不能保压，工作风缸指示压力下降，为___泄漏。
【单选题】
15．JZ-7型空气制动机自阀制动后，工作风缸泄漏时，其压力___，机车自然缓解。
【单选题】
18．遮断阀管8直接与大气连通时，使中继阀___缓解作用。
【单选题】
19．单阀调整阀用来调整___的最高充气压力，并控制其压力变化，使机车产生或消除单独制动的作用。
A. 单独缓解管
B. 单独作用管
C. 作用阀作用管
【单选题】
20．___根据制动管压力变化，控制作用风缸的压力变化。
【单选题】
21．作用阀根据___内空气压力的变化，控制机车制动缸的充气或排气。
A. 作用管
B. 作用风缸
C. 作用风缸或作用管
【单选题】
22．燃油在气缸内燃烧不充分是由于喷油器___所造成。
A. 调整失败
B. 调整压力过低
C. 调整压力过高
【单选题】
23．运行中柴油机突然停机，属于柴油机方面的原因之一___故障。
A. 1~2YJ
B. 柴油机主机油泵
C. 柴油机水泵
