【单选题】
(5)Whicl of the following is a physiological process with negative feedback?___
A. blood coagulation
B. process of passing urine
C. sino-aortic baroreceptor reflex
D. process of parturition
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【单选题】
(6)Which of the following is not the characteristic of regulation by hormone?___
A. diffusenin nature
B. longer in duration
C. accurate in action
D. action in overcorrection
【单选题】
7)Which of the following is not the characteristic of cells?___
A. They are bound by the plasma membrane
B. They have the ability to break down large molecules to smaller ones to Liberate energy for their activities
C. They possess a nucleus which contains genetic information in the form of deoxyribonucleicacid(DNA).
D. Living cells can not transform materials.
【单选题】
8)The breakdown of large molecules to smaller ones is called___
A. respiration
B. anabolism
C. catabolism
D. absorption
【单选题】
9) Which of the following descriptions about the characteristics of nervous regulation is wrong?___
A. It responds fast
B. It acts exactly
C. It responds slowly.D.
D. uration is short
【单选题】
10)Which of the following descriptions about the control of body function is wrong?___
A. Homeostasis is kept by feedback control.
B. Negative feedback minimizes the changes, leading to stability.
C. Positive feedback is not useful.
D. Feed-forward makes human body foresee and adapt itself to the environment promptly.
【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
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【多选题】
积极促进“一带一路”国际合作，努力实现___、____、____、____、____，打造国际合作新平台，增添共同发展新动力。
A. 政策沟通
B. 设施联通
C. 贸易畅通
D. 人员互通
E. 资金融通
F. 民心相通
【多选题】
要深刻认识党面临的___的长期性和复杂性。
A. 执政考验
B. 改革开放考验
C. 市场经济考验
D. 生态保护考验
E. 外部环境考验
【多选题】
新时代党的建设总要求是___。
A. 坚持和加强党的全面领导，坚持党要管党、全面从严治党
B. 以加强党的长期执政能力建设、先进性和纯洁性建设为主线，以党的政治建设为统领，以坚定理想信念宗旨为根基，以调动全党积极性、主动性、创造性为着力点
C. 全面推进党的政治建设、思想建设、组织建设、作风建设、纪律建设
D. 把制度建设贯穿其中，深入推进反腐败斗争，不断提高党的建设质量
E. 把党建设成为始终走在时代前列、人民衷心拥护、勇于自我革命、经得起各种风浪考验、朝气蓬勃的马克思主义执政党
【多选题】
领导十三亿多人的社会主义大国，我们党既要政治过硬，也要本领高强。要___。
A. 增强学习本领，增强政治领导本领
B. 增强改革创新本领，增强科学发展本领
C. 增强依法执政本领，增强群众工作本领
D. 增强狠抓落实本领，增强驾驭风险本领
【多选题】
以___、____、____、____、____，把党内和党外、国内和国外各方面优秀人才集聚到党和人民的伟大奋斗中来。
A. 识才的慧眼
B. 敬才的风度
C. 爱才的诚意
D. 用才的胆识
E. 容才的雅量
F. 聚才的良方
【多选题】
青年兴则国家兴，青年强则国家强。青年一代___、____、____，国家就有前途，民族就有希望。
A. 有品德
B. 有理想
C. 有本领
D. 有担当
【多选题】
全党全国各族人民要紧密团结在党中央周围，高举中国特色社会主义伟大旗帜，锐意进取，埋头苦干，为实现推进现代化建设、完成祖国统一、维护世界和平与促进共同发展三大历史任务，为___继续奋斗！
A. 决胜全面建成小康社会
B. 夺取新时代中国特色社会主义伟大胜利
C. 全面建成社会主义现代化强国
D. 实现中华民族伟大复兴的中国梦
E. 实现人民对美好生活的向往
【多选题】
各级党组织和全体党员要带头___，任何组织和个人都不得有超越宪法法律的特权，绝不允许以言代法、以权压法、逐利违法、徇私枉法。
【多选题】
司法部大力推进公共法律服务平台建设。今年8月出台了《关于推进公共法律服务平台建设的意见》《12348中国法网（中国公共法律服务网）建设指南》等一系列政策文件，9月召开了推进公共法律服务平台建设电视电话会议，对平台建设进行了全面部署，着力打造___、、三大平台。
【多选题】
加大全民普法力度，建设社会主义法治文化，树立___、的法治理念。
A. 宪法法律至上
B. 宪法至上
C. 法律面前人人平等
D. 宪法面前人人平等
【多选题】
几乎与十九大召开同时，两项有关律师制度改革重大举措出台，分别是___试点工作和试点工作。
A. 司法行政（法律服务）案例库建设
B. 刑事案件律师辩护全覆盖
C. 律师调解
【多选题】
党组织和党员必须牢固树立___，自觉遵守党章，严格执行和维护党的纪律，自觉接受党的纪律约束，模范遵守国家法律法规。
A. 政治意识
B. 大局意识
C. 核心意识
D. 看齐意识
【多选题】
对党员的纪律处分种类有___
A. 警告
B. 严重警告
C. 撤销党内职务
D. 留党察看
E. 开除党籍
【多选题】
运用监督执纪“四种形态”，经常___。
A. 开展批评和自我批评、约谈函询，让“红红脸、出出汗”成为常态
B. 党纪轻处分、组织调整成为违纪处理的大多数
C. 党纪重处分、重大职务调整的成为少数
D. 严重违纪涉嫌违法立案审查的成为极少
【多选题】
根据《中国共产党纪律处分条例》，有下列情形之一的，应当从重或者加重处分___.
A. 强迫、唆使他人违纪的；
B. 拒不上交或者退赔违纪所得的；
C. 违纪受处分后又因故意违纪应当受到党纪处分的；
D. 违纪受到党纪处分后，又被发现其受处分前的违纪行为应当受到党纪处分的；
【多选题】
政治品行恶劣，___造成损害或者不良影响的，情节严重的，给予开除党籍处分。
A. 匿名诬告
B. 有意陷害或制造其他谣言
C. 受到行政拘留
D. 受到法律、行政法规规定的其他行政处罚
【多选题】
违反民主集中制原则，故意规避集体决策，决定___，给予警告或者严重警告处分；情节严重的，给予撤销党内职务或者留党察看处分。
A. 重大事项
B. 重要干部任免
C. 重要项目安排
D. 大额资金使用
【多选题】
___配偶、子女及其配偶等亲属、身边工作人员和其他特定关系人利用党员干部本人职权或者职务上的影响谋取私利，情节较轻的，给予警告或者严重警告处分。
【多选题】
借用___的钱款、住房、车辆等，影响公正执行公务，情节较重的，给予警告或者严重警告处分。
A. 管理对象
B. 服务对象
C. 亲属
D. 朋友
【多选题】
对于严重违犯党的纪律、本身又不能纠正的党组织，上一级党的委员会在查明核实后，根据情节严重的程度，可以予以___。
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利用___等决策、审批过程中掌握的信息买卖股票，利用职权或者职务上的影响通过购买信托产品、基金等方式非正常获利的，情节较重的，给予撤销党内职务或者留党察看处分；情节严重的，给予开除党籍处分。
A. 参与企业重组改制
B. 定向增发
C. 兼并投资
D. 土地使用权出让
【多选题】
盲目___，搞劳民伤财的“形象工程”、“政绩工程”，致使国家、集体或者群众财产和利益遭受较大损失的，对直接责任者和领导责任者，给予警告或者严重警告处分；情节严重的，给予撤销党内职务、留党察看或者开除党籍处分。
A. 举债
B. 铺摊子
C. 上项目
D. 进行企业改制
【多选题】
违反民主集中制原则，违反议事规则，___决定重大问题的,给予警告或者严重警告处分；情节严重的，给予撤销党内职务或者留党察看处分。
A. 个人
B. 少数人
C. 领导干部
D. 上级领导
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拒不执行党组织的___等决定的，给予警告、严重警告或者撤销党内职务处分。
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侵犯党员的___和被选举权，情节较重的，给予警告或者严重警告处分；情节严重的，给予撤销党内职务处分。
A. 表决权
B. 名誉权
C. 隐私权
D. 选举权
【多选题】
违反有关规定自定薪酬或者滥发津贴、补贴、奖金等，对___，情节较轻的，给予警告或者严重警告处分；情节较重的，给予撤销党内职务或者留党察看处分；情节严重的，给予开除党籍处分。
A. 直接责任者
B. 主要领导
C. 会计
D. 领导责任者
【多选题】
在长期的革命、建设、改革过程中，已经结成由中国共产党领导的，有各民主党派和各人民团体参加的，包括___的广泛的爱国统一战线，这个统一战线将继续巩固和发展。
A. 全体社会主义劳动者
B. 社会主义事业的建设者
C. 拥护社会主义的爱国者
D. 拥护祖国统一和致力于中华民族伟大复兴的爱国者
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人民行使国家权力的机关是全国人民代表大会和地方各级人民代表大会。人民依照法律规定，通过各种途径和形式，管理___。
A. 国家事务
B. 经济事业
C. 社会事务
D. 文化事业
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国家保障各少数民族的合法的权利和利益，维护和发展各民族___的关系。
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全国人民代表大会常务委员会的组成人员不得担任下列___的职务。
A. 国家行政机关
B. 监察机关
C. 审判机关
D. 检察机关
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中华人民共和国设立国家监察委员会和地方各级监察委员会。监察委员会由下列___人员组成。
A. 主任
B. 副主任若干
C. 委员若干
D. 秘书长
【多选题】
依据宪法，监察机关办理职务违法和职务犯罪案件，应当与___互相配合，互相制约。
A. 审判机关
B. 检察机关
C. 行政机关
D. 执法部门
【多选题】
国家监察工作应遵守的原则有___。
A. 严格遵照宪法和法律，以事实为根据，以法律为准绳
B. 在适用法律上一律平等，保障当事人的合法权益
C. 权责对等，严格监督
D. 惩戒与教育相结合，宽严相济
【多选题】
监察委员会依照本法和有关法律规定履行___职责。
【多选题】
依照国家监察法和有关法律规定监察委员会的职责为___。
A. 对公职人员开展廉政教育，对其依法履职、秉公用权、廉洁从政从业以及道德操守情况进行监督检查
B. 对涉嫌贪污贿赂、滥用职权、玩忽职守、权力寻租、利益输送、徇私舞弊以及浪费国家资财等职务违法和职务犯罪进行调查
C. 对违法的公职人员依法作出政务处分决定
D. 对履行职责不力、失职失责的领导人员进行问责；
E. 对涉嫌职务犯罪的，将调查结果移送人民检察院依法审查、提起公诉；向监察对象所在单位提出监察建议。
【多选题】
关于各级监察机关的监察事项的管辖权限问题，下列说法正确的是___。
A. 上级监察机关可以办理下一级监察机关管辖范围内的监察事项，必要时也可以办理所辖各级监察机关管辖范围内的监察事项。
B. 监察机关之间对监察事项的管辖有争议的，由其共同的上级监察机关确定。
C. 上级监察机关可以将其所管辖的监察事项指定下级监察机关管辖，也可以将下级监察机关有管辖权的监察事项指定给其他监察机关管辖。
D. 监察机关认为所管辖的监察事项重大、复杂，需要由上级监察机关管辖的，可以报请上级监察机关管辖。
【多选题】
监察机关及其工作人员对监督、调查过程中知悉的___，应当保密。
A. 国家秘密
B. 商业秘密
C. 个人隐私
D. 舆情信息
【多选题】
各级监察委员会可以向___以及所管辖的行政区域、国有企业等派驻或者派出监察机构、监察专员。
A. 本级中国共产党机关
B. 国家机关
C. 法律法规授权或者委托管理公共事务的组织和单位
D. 基层群众性自治组织
【多选题】
监察机关根据监督、调查结果，有权对违法的公职人员依照法定程序作出___、撤职、开除等政务处分决定。
【多选题】
监察机关应当依法公开监察工作信息，接受___。
A. 民主监督
B. 社会监督
C. 舆论监督
D. 行政监督
