【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
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【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
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【单选题】
"436.☆柜员发生现金长、短款差错，金额在等值人民币（）以上的，应立即向上级单位报告,各单位应在24小时之内口头上报总行运营管理部。___
A. 1,000元（含）
B. 5,000元（含）
C. 10,000元（含）
D. 50,000元（含）"
【单选题】
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A. 网点派驻团队
B. 分行运营管理部门
C. 总行运营管理部门
D. 总行现金中心"
【单选题】
"438.☆各营业机构应（）不定时进行库存检查，对营业机构所有的库存现金（含自助机具钞箱现金）进行清点核对，并做好查库记录。___
A. 每周
B. 每两周
C. 每月
D. 每季度"
【单选题】
"439.☆我行影像交换系统目前处理的全国支票限定金额为（）（含）以下。___
A. 10万元
B. 30万元
C. 50万元
D. 100万元"
【单选题】
"440.☆☆提回票据票面金额与票据磁码金额不符，应作退票处理，在下一场交换按（）退原提出行。___
A. 票据磁码金额
B. 票面金额
C. 客户确认金额
D. 原提出行确认金额"
【单选题】
"441.☆☆同城票据交换的托收票据不包括（）。___
A. 贷记凭证
B. 支票
C. 汇票
D. 本票"
【单选题】
"442.☆☆定期开户申请书上预留私章为代理人章的，还需提供（）。___
A. 代理人身份证件
B. 经办人身份证件
C. 法定代表人授权书
D. 单位授权书"
【单选题】
"443.☆☆验印环节，若是支付密码户，支付密码正确，但单位财务专用章与预留印鉴内容不符，选择（）。___
A. 验印通过
B. 印鉴形式审核不通过退票
C. 印鉴与预留印鉴不符退票
D. 支付密码未通过退票"
【单选题】
"444.☆中国人民银行规定的全国支票的回执返回期为（）。___
A. T+0
B. T+1
C. T+2
D. T+3"
【单选题】
"445.☆“重要信息系统”是指，（）的信息系统，其信息安全和系统服务安全关系公民、法人和组织的权益或社会秩序和公共利益，甚至影响国家安全的信息系统。___
A. 重要业务的所有业务环节所依赖
B. 重要业务的关键业务环节所依赖
C. 重要业务所依赖
D. 重要业务最主要的一个环节所依赖"
【单选题】
"446.☆根据监管规定，全面的业务影响分析应至少（）开展一次。___
【单选题】
"447.☆业务恢复时间目标和重要业务恢复点目标的英文缩写为业务（）___
A. RTO和RPO
B. RPO和RTO
C. BTO和BPO
D. BPO和BTO"
【单选题】
"448.☆☆原则上重要业务恢复时间目标不得大于（），重要业务恢复点目标不得大于（）。___
A. 2小时、1小时
B. 3小时、1小时
C. 4小时、半小时
D. 以上都不对"
【单选题】
"449.☆纳入全行业务连续性管理的重要业务演练应（）全覆盖。___
A. 三年内
B. 二年内
C. 四年内
D. 以上都不对"
【单选题】
"450.☆☆在业务服务时段导致全行重要业务全面停顿，或两个（含）以上省（自治区、直辖市）重要业务无法正常开展达（）（含）以上，或一个省（自治区、直辖市）重要业务无法正常开展达（）（含）以上为特别重大运营中断事件___
A. 1、3
B. 2、5
C. 3、6
D. 3、5"
【单选题】
"451.☆（）预案用于在发生运营中断事件后，规范、指导运营中断事件处置过程中常面临的危机管理和保障性行动措施,包括安全保卫、监管沟通、媒体公关、应急所需资金、后勤保障、法律事务等方面。___
A. 支持保障
B. 信息系统
C. 业务
D. 专项"
【单选题】
"452.☆发生运营中断事件，事发单位应在（）分钟内完成向本级综合管理部门、业务连续性主管部门、相关职能部门的口头报告，并原则上在（）小时内提交书面正式报告___
A. 15、2
B. 30、2
C. 30、1
D. 15、1"
【单选题】
"453.☆业务场所发生火灾等灾难性事件时，事发单位现场负责人应迅速做出灾难判断及应急疏散决定，重点保障（）。___
A. 场所安全
B. 系统安全
C. 财产安全
D. 人员安全"
【单选题】
"454.☆总行（）是业务连续性管理执行部门，负责业务连续性管理中信息技术应急响应与恢复相关工作___
A. 运营管理部
B. 信息技术部
C. 各业务部门
D. 各支持保障部门"
【单选题】
"455.☆总行（）负责就运营中断事件相关事宜，向与重大突发事件、重要事项报告相应的外部监管机构的归口管理部门进行报告___
A. 办公室
B. 运营管理部
C. 法律合规部
D. 人力资源部"
【单选题】
"456.☆我行在完成业务连续性计划的全行性演练后，应当在（）个工作日内向监管机构提交演练总结报告。___
【单选题】
"457.☆（）根据设定的运营中断事件发生的场景，实地演习整个处理过程，使所有相关人员切实参与，掌握运营中断事件处理方法和过程，同时检查存在的不足。___
A. 沙盘演练
B. 模拟演练
C. 实战演练
D. 桌面演练"
【单选题】
"458.☆总行审计部应每年对我行业务连续性管理进行审计，每（）至少开展一次全面审计___
【单选题】
"459.☆各单位应加强业务连续性管理（），确保各级员工获得业务连续性管理方面的足够知识，以提高各级员工业务连续性管理意识。___
A. 宣传
B. 教育
C. 培训
D. 以上都是"
【单选题】
"460.☆发生运营中断事件时，应据以进行事件的评估分级，并基于分级结果进行（）的应对处置。___
A. 差异化
B. 统一
C. 快速
D. 有效"
【单选题】
"461.☆☆高级管理层下设（），作为全行业务连续性管理的领导机构，对高级管理层负责___
A. 业务连续性管理执行部门
B. 业务连续性管理办公室
C. 业务连续性管理委员会
D. 以上都不对"
【单选题】
"462.☆总行运维申请原则上在每个工作日（）前提交至总行运维操作部门。___
A. 16:00
B. 16:30
C. 17:00
D. 17:30"
【单选题】
"463.☆运维申请的登陆网址及选择路径为文档一体化系统内“日常管理”模块下（）进行发起和审批。___
A. 互联网使用申请
B. 科技需求审批流程
C. 工作联系单
D. 业务系统运维申请"
【单选题】
"464.☆安全发卡系统用户密码不应包含（）。___
A. 字母
B. 数字
C. 特殊字符
D. 中文"
【单选题】
"465.☆（）是发卡系统的管理部门，也是业务应用管理部门之一。___
A. 总行运营管理部
B. 总行零售业务部
C. 总行信用卡中心
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【单选题】
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A. 1小时
B. 2小时
C. 3小时
D. 1天"
【单选题】
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A. 业务受理单
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【单选题】
"471.☆会计档案统一影像调阅功能，分行辖内用户由（）建立。___
A. 总行
B. 分行系统管理员
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A. 次年
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C. 2年
D. 不用上交"
【单选题】
"473.☆()作为会计档案的归口管理部门，制定会计档案管理制度和管理要求，负责对全行会计档案管理工作进行指导、检查、监督、评价、培训等工作。___
A. 总行运营管理部
B. 总行信息技术部
C. 总行计划财务部
D. 各分行管理部"
【单选题】
"474.☆（）负责系统交易形成的电子档案（即系统服务器生成/备份的电子档案）的保管工作。___
A. 总行运营管理部
B. 总行信息技术部
C. 总行计划财务部
D. 各分行管理部"
【单选题】
"475.☆（）负责财务类会计档案日常管理工作。___
A. 总行运营管理部
B. 总行信息技术部
C. 总行计划财务部
D. 各分行管理部"
