【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
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相关试题
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
推荐试题
【单选题】
衿翼扭力限制器在什么位置?___
A. A.作动筒齿轮箱.
B. B.作动筒驱动臂.
C. C.支持轴承.
D. D.PCU.
【单选题】
哪个传感器用于衿,缝翼ECAM显示?___
A. A.APPU.
B. B.FPPU.
C. C.IPPU.
D. D.LVDT.
【单选题】
哪里选择点火A和B?___
A. A.发动机面板
B. B.ECAM控制面板
C. C.EEC.
D.
【单选题】
哪些计算机接受侧杆指令?___
A. A.ELAC.
B. B.FCDC
C. C.FAC,ELAC,SEC
D. D.FMGC
【单选题】
扭力限制器在什么地方?___
A. A.扭力轴
B. B.作动筒
C. C.PCU输出轴.
D.
【单选题】
扰流板在地面怎样人工放出?___
A. A.液压系统释压,使用维护开锁装置.
B. B.按压SEC电门.
C. C.使用维护开锁装置,并按压SEC电门.
D. D.保持液压并使用维护开锁装置.
【单选题】
扰流板在飞机接地时自动放出的条件是?___
A. A.扰流板手柄预位,油门手柄在慢车或反推位.
B. B.扰流板手柄不预位,油门在慢车位.
C. C.只要油门在反推位.
D. D.要扰流板手柄预位.
【单选题】
若滑油田油滤堵塞,则:___
A. A.驾驶舱内触发滑油滤堵塞警告
B. B.油滤上的目视堵塞指示器变为红色
C. C.滑油低压电门闭合.
D.
【单选题】
升降舵作动筒有什么工作方式?___
A. A.主动,随动
B. B.空中
C. C.A和B.
D.
【单选题】
什么用来防止金属粒子进入滑油田油泵:___
A. A.一个主金属屑探测器
B. B.回油滤
C. C.6个磁性金属屑探测器及泼、网.
D.
【单选题】
推力控制组件将推力手柄位置信号传送到:___
A. A.燃调组件
B. B.发动机接口组件(EIU)
C. C.EEC的两个通道.
D.
【单选题】
怎样知道水平安定面作动筒卡阻。___
A. A.头顶板上卡阻灯.
B. B.水平安定面作动筒卡阻指示器.
C. C.A检.
D. D.ECAM信息.
【单选题】
A319/320飞机每边的大翼上有5块扰流板，其中横滚扰流板、减速板、地面扰流板分别有块？___
A. 5、4、3；
B. 4、3、5；
C. 3、4、5。
D.
【单选题】
A319/320飞机每边的大翼上有5块扰流板，其中减速扰流板为？___
A. 2、3、4、5；
B. 2、3、4；
C. 1、2、3、4、5。
D.
【单选题】
A320飞机的主飞行操纵是通过传统的飞行操纵面来完成的。所有的飞行操纵面均为电控液压操纵，C除正常的电传操纵外还各有一套备用的机械操纵系统。___
A. 方向舵及可配平水平安定面（THS）；
B. 升降舵和方向舵；
C. 升降舵及可配平水平安定面（THS）
D.
【单选题】
EFCS包括D，计算机系统时刻控制并监控飞行操纵面，同时记录并存储故障。___
A. ELACS、SECS、FCDCS；
B. ELACS、SECS；
C. ELACS、SECS和垂直加速度计；
D. ELACS，SECS，FCDCS和垂直加速度计。
【单选题】
EFCS系统中两部FCDC将D与其它飞机系统隔离开，用于维护和数据采集。___
A. SEC；
B. ELAC；
C. FAC；
D. SEC+ELAC。
【单选题】
ELAC1由直流主汇流条（4PP）供电，当A时，电瓶1通过专用的二极管设备（电源供给切断组件）取代供电。___
A. 4PP汇流条电压降至电瓶输出电压以下；
B. 在地面二发关车后30秒；
C. 直流正常汇流条2PP故障时。
D.
【单选题】
FWC与哪一部EFCS计算机相？___
A. SECS；
B. ELACS和SECS；
C. 只与FCDCS相连。
D.
【单选题】
LGCIU从哪些传感器接收信息___
A. 全部四个脱开传感器；
B. 每边大翼一个传感器；
C. 一边大翼上的两个传感器。
D.
【单选题】
THS的钢索张力由A保持恒定？___
A. 钢索张力补偿器；
B. 钢索张力人工调节器；
C. 人工感觉机构。
D.
【单选题】
THS作动器的输入轴2号驱动马达可由C控制？___
A. ELAC1；
B. ELAC2；
C. ELAC1或SEC1；
D. SEC2。
【单选题】
WTB（翼尖刹车）位于何处___
A. 位于翼尖，APPU外侧；
B. 在每一边大翼的11和12滑轨之间；
C. 在每一边大翼的7和8号滑轨之间。
D.
【单选题】
半速监控何时工作___
A. 当方向valve通电时；
B. 当控制valve在全速位置时；
C. 始终工。
D.
【单选题】
当C时偏航阻尼作动器处于旁通模式？___
A. 液压压力下降；
B. 一个电磁valve断电；
C. A+B。
D.
【单选题】
当电源故障时对应的扰流板液压保持在收起位；当液压故障时，伺服机构液压锁定在防止扰流板放出的方向上。在上述两种情况下，与之对称的扰流板。___
A. 仍能正常工作；
B. 也被抑制；
C. 前者不受影响，后者将被抑制。
D.
【单选题】
当横滚和减速板指令之和超过扰流板最大作动角度时___
A. 减速板功能被抑制；
B. 所有的扰流板将收到附加的放出指令；
C. 对称的扰流板将收回一定的角度，使得两个舵面的角度差等于横滚指令。
D.
【单选题】
当襟翼/缝翼构型为1+F，CAS达到210节时。___
A. 襟翼自动收回到0位，襟缝翼构型变为1；
B. 因为速度太大，襟翼自动放出；
C. 因为速度太大alphalock功能衔接。
D.
【单选题】
当襟翼PCU滑阀卡阻时，将触发何种警告___
A. 一级警告；
B. 二级警告；
C. 三级警告。
D.
【单选题】
当两个侧杆运动方向相同或相反时：___
A. 舵面运动与两个侧杆的运动矢量和成正比；
B. 舵面运动与最后一个侧杆杆的运动成正比；
C. 舵面运动与带一个侧杆的运动成正比。
D.
【单选题】
当两个液压系统失效时，THS作动器将。___
A. THS将保持在最后的位置；
B. THS将回到中立位置；
C. 此时仍然可以通过钢索机械操纵THS。
D.
【单选题】
当你按压控制面板上的复位按钮时，可以通过D复位方向舵至零位。___
A. FCDCS；
B. SECS；
C. ELACS；
D. FACS。
【单选题】
当同一边副翼的两套伺服系统均无液压时，两套伺服系统。___
A. 自动转为阻尼模式；
B. 自动工作于定中模式；
C. 自动工作于随动模式。
D.
【单选题】
当一边升降舵的两套伺服机构均电操纵故障时，伺服机构自动转为A，当一边升降舵的双液压均失效时，自动工作于___
A. 定中模式；
B. 阻尼模式；
C. 工作模式。
D.
【单选题】
当一个侧杆的转换按钮按压超过40s时：___
A. 在松开转换按钮后，另一侧杆不起作用；
B. 在松开转换按钮后，另一侧杆仍然有效；
C. 两侧杆均不起作用。
D.
【单选题】
当一个电配平马达故障时。___
A. THS电配平失效；
B. THS半速配平；
C. THS电配平完全可用。
D.
【单选题】
当一个襟翼的PCU马达不工作时会有什么后果？___
A. 襟翼的运动不受影响；
B. 系统被锁住，襟翼无法作动；
C. 襟翼以半速运动。
D.
【单选题】
当一个液压系统失效时，THS作动器将。___
A. 由另一液压系统驱动以半速工作；
B. 此时相应的POB和NO-BACKBRAKE工作；
C. 由另一液压系统驱动以全速工作。
D.
【单选题】
当自动驾驶衔接时飞机稳定前行时，在控制面板上最大允许的方向舵配平限制显示是。___
A. 右1度和左23度；
B. 左右各20度；
C. 左1度和右23度。
D.
【单选题】
地面扰流板的预选的必要条件是什么?___
A. 两个油门杆在慢车位；
B. 地面扰流板在预备位，且两个油门杆在慢车位；
C. 地面扰流板在预备位，且两个油门杆在慢车位，一个在反推位，另一个不超过慢车位。
D.
