【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
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相关试题
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
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【单选题】
扒砟时，扒开的道床的长度自钢轨中心向两侧（）mm。 ___
A. 300
B. 400
C. 450
D. 500
【单选题】
扒砟时，扒开的道床的深度距轨枕边不少于（）mm。 ___
【单选题】
扒砟时，要保证枕木盒内有（）的石砟。 ___
A. 三分之二
B. 二分之一
C. 三分之一
D. 四分之一
【单选题】
在使用捣鼓机时，要启动捣鼓机运转（）min,检查电机各部温升是否正常。 ___
A. 1~3
B. 2~3
C. 3~5
D. 1~7
【单选题】
捣鼓范围为钢轨两侧各不少于（)mm。 ___
A. 100
B. 450
C. 300
D. 200
【单选题】
无缝线路轨温超过锁定轨温（）℃是禁止作业。 ___
A. 20
B. 21
C. 22.5
D. 25
【单选题】
使用吊轨车每次运载不超过（）公斤。 ___
A. 450
B. 500
C. 650
D. 750
【单选题】
使用吊轨车吊短轨的长度不超过（）米。 ___
【单选题】
进行打磨时，非操作人员应离开作业区至少（）米以上。 ___
【单选题】
进行锯轨时，非操作人员应离开作业区至少（）米以上。 ___
【单选题】
一组道岔中的叉心部分需要量几处。 ___
【单选题】
正线中一组道岔中的第二处的轨距为（）。 ___
A. 1435
B. 1440
C. 1445
D. 1450
【单选题】
车辆段中一组道岔中的第二处的轨距为（）。 ___
A. 1435
B. 1440
C. 1445
D. 1450
【单选题】
在测量现场正矢中存在肥边，肥边大于（）mm应铲除之。 ___
【单选题】
地铁正线采用（）道床，停车场采用（）道床。 ___
A. 无咋，有咋
B. 无咋，无咋
C. 有咋，有咋
D. 有咋，无咋
【单选题】
尖轨动程规定在第（）连接杆(拉杆)中心处测量 ___
【单选题】
正线线路中钢轨上的R代表（）。 ___
A. 超高
B. 一个字母
C. 正矢点
D. 半径
【单选题】
正线线路中钢轨上的H代表（）。 ___
A. 超高
B. 一个字母
C. 正矢点
D. 半径
【单选题】
正线线路中钢轨上的F代表（）。 ___
A. 超高
B. 一个字母
C. 正矢点
D. 半径
【单选题】
菱形道岔如何判定右股（）。 ___
A. 随意
B. 面向停车场或者车站左边
C. 都可以
D. 面向停车场或者车站右边
【单选题】
菱形道岔如何判定左股（）。 ___
A. 随意
B. 面向停车场或者车站左边
C. 都可以
D. 面向停车场或者车站右边
【单选题】
2号线正线60kg/m，9号单开道岔AT弹性可弯尖轨直向过岔允许最高速度为（）km/h。 ___
A. 60
B. 80
C. 120
D. 100
【单选题】
4号线正线60kg/m，9号单开道岔AT弹性可弯尖轨直向过岔允许最高速度为（）km/h。 ___
A. 140
B. 100
C. 120
D. 80
【单选题】
正线开通初期3个月内每（）小时巡道一次，3个月后视情况可改为每（）小时巡道一次。 ___
A. 24 24
B. 24 48
C. 48 48
D. 48 72
【单选题】
人工巡道的周期间隔不应超过（）小时。 ___
【单选题】
车辆段、停车场所有道岔（）巡查一遍，特殊情况下，根据调度部门下发的施工计划执行。 ___
A. 24h
B. 48h
C. 72h
D. 每周
【单选题】
正线折返道岔、车辆段、停车场咽喉道岔应每（）全面检查一次。 ___
A. 每周
B. 每3天
C. 每两周
D. 每两天
【单选题】
正线普通道岔（）全面检查一次。 ___
【单选题】
正线道岔每（）检查一次钢轨、轨端、尖轨、叉心等是否有肥边和波磨，并计划安排打磨。 ___
【单选题】
正线及车辆段、停车场道岔每（）检查一次钢轨、轨端、尖轨、叉心等是否有肥边和波磨，并有计划安排打磨。 ___
【单选题】
每年在（)季来临之前完成正线所有道岔及车辆段、停车场咽喉道岔的辙叉部分趾端和跟端接头拆检并涂油。 ___
【单选题】
每年（）月完成所有道岔和道岔前后轨缝调查和轨缝均匀工作并做好记录。 ___
【单选题】
50kg/m钢轨曲线型尖轨7号道岔设计动程：（）mm。 ___
A. 160
B. 152
C. 120
D. 80
【单选题】
道岔两尖轨尖端相错量不得超过( )mm。 ___
