【单选题】
Q4: Which of the following is the disadvantage of long commutes?___
A. Traffic jams .
B. Expensive housing .
C. Poorer life quality .
D. A tiring and boring trip .
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相关试题
【单选题】
Q1: What did Katy like about Jason’s last Halloween party?___
A. She liked playing an interesting game .
B. She enjoyed seeing many of her old friends .
C. She enjoyed wearing her Halloween costume .
D. She liked the decorations in Jason's front yard .
【单选题】
Q2: What is the actual reason that Katy doesn’t want to attend Jason’s party?___
A. None of her friends likes Jason .
B. None of Jason's guests is young .
C. She wants to go to Linda's party ..
D. She went to Jason's party last year .
【单选题】
Q3: What is special about Linda’s party?___
A. The party will last four hours .
B. Six people will attend the party .
C. They will have huge bags of candy .
D. They will play a new game called "GuessWho ".
【单选题】
Q4: What will Katy do to solve her problem?___
A. Go to Jason's party .
B. Go to Linda's party .
C. Attend both Jason's and Linda's parties .
D. Celebrate Halloween with her parents .
【单选题】
Q1: What is special about this year’s Black Friday shopping?___
A. Some stores offered bigger holiday discounts .
B. Some stores provided more choices of nightlife.
C. Some stores made efforts to attract young people .
D. Some stores opened much earlier than they used to .
【单选题】
Q2: Why did some stores open at midnight on Thanksgiving night?___
A. To attract young customers .
B. To beat other stores for sale.
C. To let people sleep late the next day .
D. To keep people stay up for the night .
【单选题】
Q3: How many Black Friday shoppers were reported to go to the shops at midnight this year?___
A. 24 percent .
B. 37 percent .
C. 9.5 percent .
D. 23.5 percent .
【单选题】
Q4: What can we learn about the 15-year-old Jenny?___
A. She and her cousins went back home at midnight .
B. She liked the traditional 4 a.m. Black Friday.
C. She preferred midnight shopping to early morning shopping .
D. She and her cousins got up very early to buy discounted items .
【单选题】
Q1: Why did the woman decide to do a triathlon?___
A. Because she did it in college .
B. Because she wanted to be tough .
C. Because her sister did it and liked it .
D. Because her sister said it was good for her .
【单选题】
Q2: When did the man first do a triathlon?___
A. Last year .
B. In college .
C. Last week .
D. In high school .
【单选题】
Q3: How does the man feel about running?___
A. Boring.
B. Scaring .
C. Exciting .
D. Interesting .
【单选题】
Q4: Why doesn’t the woman like swimming in the triathlon?___
A. Because she fears that a big fish might eat her .
B. Because she fears that she would get lost in lakes .
C. Because she doesn't want to scare away small fishes .
D. Because she doesn't like swimming with many people .
【单选题】
Q1: What is the ratio of positive to negative emotions that can make a person happier?___
A. 1:3.
B. 3 :1.
C. 1 :10 .
D. 10 :1.
【单选题】
Q2: What is the most exciting finding about increasing positive emotions?___
A. It improves relationships .
B. It leads to greater success .
C. It helps develop creativity .
D. It contributes to good health .
【单选题】
Q3: What does the speaker say about negative feelings?___
A. People should turn every negative feeling around .
B. Negative feelings can sometimes have positive effects .
C. Negative feelings often cause people to make mistakes .
D. People should never show negative feelings in public places .
【单选题】
Q4: What is the main idea of the passage?___
A. People should learn to manage their emotions .
B. People should be patient with their negative feelings .
C. People should learn to analyze causes of unhappiness .
D. People should identify as many positive feelings as possible .
【单选题】
Q1: What are the man and woman talking about?___
A. Whether nature is magical and kind .
B. Whether nature is powerful and full of risks .
C. Whether Christopher was well prepared for the trip .
D. Whether Christopher's trip to Alaska was worthwhile .
【单选题】
Q2: What can we learn about Christopher?___
A. He made a film about his trip to Alaska .
B. He wrote a story about his trip to Alaska .
C. He died while having an adventure in Alaska .
D. He learned how powerful and risky Alaska was .
【单选题】
Q3: What does the woman think about Christopher taking the trip to Alaska?___
A. He was too foolish .
B. He was really romantic .
C. He had a very kind heart .
D. He had a spirit for trying things .
【单选题】
Q4: Which of the following is NOT mentioned as something that would have saved Christopher’s life?___
A. A gun to hunt .
B. The map of the area .
C. Emergency food supplies .
D.
E. mergency communication equipment .
【单选题】
Q1: What speed can an avalanche reach within five seconds of taking off?___
A. At 8 miles an hour .
B. At 18 miles an hour .
C. At 80 miles an hour .
D. At 88 miles an hour .
【单选题】
Q2: According to the passage, under what circumstances may an avalanche occur?___
A. There are too many layers of snow on the .
B. There is a layer of snow covering an entire area .
C. The top layer of snow slides off the layer below it .
D. The layer of snow below the surface becomes unstable .
【单选题】
Q3: What are skiers advised to do to avoid being caught in an avalanche?___
A. Ski only in the official ski areas .
B. Look for solid snow to walk on .
C. Look out for each other while skiing .
D. Learn to control themselves in an avalanche .
【单选题】
Q4: Why does the ski patrol use explosives?___
A. To dig holes in the snow .
B. To close the area for skiing .
C. To make an avalanche move on purpose .
D. To' check how different layers are holding up .
【单选题】
Q1:What is conversation mainly about?___
A. The woman's happy college life the man's doubt .
B. The woman's spending habits and the man's concerns .
C. The man's reminding the woman of the exam this Thursday .
D. The man's support for the woman over the past 15 years .
【单选题】
Q2:What did the woman do last night?___
A. She bought a new leather coat .
B. She studied very hard for an exam .
C. She treated all her friends to dinner .
D. She went to a concert with her friends .
【单选题】
Q3:Where did the woman get the money?___
A. She just received her student loan .
B. She saved some money for herself .
C. She borrowed the money from her friends .
D. She asked her mom to send her the money .
【单选题】
Q4:What is the man?___
A. A teacher of biology .
B. An undergraduate student .
C. A freshman in biology class .
D. A graduate teaching assistant .
【单选题】
Q1: What is this passage mainly about?___
A. How businesses can compete with each other .
B. How small businesses operate during holidays .
C. How small businesses manage holiday workers .
D. How can earn more money during holidays .
【单选题】
Q2: According to Rubin, what can small companies do to thank holiday workers?___
A. Have talks with their families .
B. Give them good extra benefits .
C. Offer them expensive holiday tokens .
D. Show appreciation to them face to face .
【单选题】
Q3: What can small business owners do to help holiday workers get into the holiday spirit?___
A. Entertain them with big meals .
B. Let them enjoy some holiday games .
C. Give them handmade thank-you cards .
D. Send their families some holiday gift cards .
【单选题】
Q4: Who are supposed to benefit most from this passage?___
A. Workers who have to work during holidays .
B. Employees who intend to earn extra money .
C. Big companies that usually close on holidays .
D. Small businesses that try to be more competitive .
【单选题】
In the first two paragraphs of the passage the writer tries to tell us that___
A. he had lived in Washington D.C. for twenty years
B. he was very imaginative when he was a child
C. he had fond memories of his old neighborhood
D. )he had come from a very poor neighborhood
【单选题】
The writer ,as a child ,was very fond of playing in the basement because ___
A. it was bright and alive
B. it contained a movie house and a space station
C. it was ideal for playing hide-and-seek
D. it was surrounded by trees and flowers
【单选题】
How did the writer feel when he visited his old neighborhood in Washington D.C. ?___
A. Greatly surprised .
B. Very regretful .
C. Quite excited .
D. Very sad .
【单选题】
On his visit to his hometown ,the writer found the old apartment building___
A. see medunfit to live in
B. had been repaired
C. could hardly be recognized
D. looked dirty and smelt horrible
【单选题】
" Youcan never go home again "inthe last sentence of this passage means that___
A. one should never revisit his hometown after many years of absence
B. one will never find his hometown the same as it was in his childhood memory
C. avisit to one's hometown will bring back one's fond memories of home
D. avisit to one's hometown will bring back many sad memorie
【单选题】
We learn from the passage that Tracy died___
A. on December 8,1992
B. of brain damage
C. 24 hours after he fell off the roof of a car
D. in a car crash
【单选题】
Tracy's parents decided to donate Tracy's organs because___
A. Tracy told them to do so just before he died
B. they wanted to save others the pain of seeing a dear one die
C. David's life could continue in a meaningful way
D. they knew David was suffering from a hopeless liver disease
【单选题】
The meeting between the writer's family and Tracy's parents was arranged because___
A. the writer and her husband wished to express their thanks to Tracy's parents
B. the local organ bank wanted to see how both families felt about the donation
C. Tracy's parents wanted to see someone whose life had been saved by the donation
D. the two families were linked by the most bittersweet ties imaginable
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【多选题】
ENESTchina中,中国CML 发病的中位年龄是( )。
【多选题】
ENESTcmr研究中,与使用伊马替尼相比, 使用达希纳实现首次MR4.5的中位时间缩短了
A. 3个月
B. 6个月
C. 1年
D. 2年
【多选题】
ENESTFreedom研究中,巩固期PCR检测频率为
A. 每4周一次
B. 每6周一次
C. 每8周一次
D. 每12周一次
【多选题】
ENESTFreedom研究中,停药后48周维持TFR的患者比例为
A. 0.442
B. 0.516
C. 0.589
D. 0.56
【多选题】
ENESTFreedom研究中,重启达希纳治疗后获得的治疗反应是指
A. 实现CCyR
B. 实现MMR
C. 实现CMR
D. 以上都正确
【多选题】
ENESTFreedom研究中,重启治疗的标准是
A. 丧失MR4.5
B. 丧失MMR
C. 丧失CCyR
D. 疾病进展
【多选题】
ENESTnd 和DASISION研究中伊马替尼二线治疗患者12个月时达MMR的比例不超过
A. 0.3
B. 0.4
C. 0.5
D. 0.6
【多选题】
ENESTnd 研究随访到5年时,达希纳300mgBID和伊马替尼组的患者中,达到MR4.5的患者的百分比是多少?
A. 32%、15%
B. 40%、 23%
C. 42%、 24%
D. 54%、 31%
【多选题】
ENESTnd 研究中,达希纳300mg BID 和伊马替尼组患者在12个月时累计的MMR率是多少?
A. 40% 和 23%
B. 54% 和 31%
C. 60% 和 31%
D. 55% 和 27%
【多选题】
ENESTnd 研究中,达希纳300mg BID 和伊马替尼组患者在三个月没有达到BCR-ABL ≤ 10%的百分比是多少?
A. 7% 和 29%
B. 7% 和 30%
C. 9% 和 30%
D. 9% 和 33%
【多选题】
ENESTnd 研究中,达希纳300mg BID 和伊马替尼组患者在以下哪个milstone的百分比分别为91%和 67%?
A. 6个月Bcr-Abl ≤ 1%
B. 6个月Bcr-Abl > 1%
C. 3个月Bcr-Abl ≤ 10%
D. 3个月Bcr-Abl > 10 %
【多选题】
ENESTnd 研究中,达希纳300mg BID组出现3-4级的胆固醇升高的人数为( )。删除
【多选题】
ENESTnd 研究中,随访到第5年时,达希纳300mgBID和伊马替尼治疗组的患者中,累积达到MMR的患者的百分比是多少?
A. 55%、27%
B. 62%、40%
C. 76%、56%
D. 77%、60%
【多选题】
ENESTnd的主要研究终点是( )。
A. 12个月时获得的MMR
B. 6个月时获得的MMR
C. 12个月时获得的CCyR
D. 12个月时获得的CCyR
【多选题】
ENESTnd试验核心研究中,有多少患者在第五年发生新的疾病进展?
【多选题】
ENESTnd研究landmark分析中,达希纳300mg BID治疗第六年哪组患者的结局百分率为94.5%?
A. 3个月BCR-ABL > 10%的患者总生存期
B. 3个月BCR-ABL ≤ 10%的患者总生存期
C. 3个月BCR-ABL > 10%的患者无进展生存
D. 3个月BCR-ABL ≤ 10%的患者无进展生存
【多选题】
ENESTnd研究landmark分析中,达希纳300mg BID治疗第五年哪组患者的结局百分率为97%?
A. 3个月BCR-ABL > 10%的患者总生存期
B. 3个月BCR-ABL ≤ 10%的患者总生存期
C. 3个月BCR-ABL > 10%的患者无进展生存
D. 3个月BCR-ABL ≤ 10%的患者无进展生存
【多选题】
ENESTnd研究随访五年时,以下哪个研究终点,达希纳300mg BID 和伊马替尼组之间反应差异率为23%?
A. MMR
B. MR4.0
C. MR4.5
D. MR5.0
【多选题】
ENESTnd研究中,达希纳300mgBID组中获得MR4.5的患者在60个月时发生疾病进展的人数为( )。
【多选题】
ENESTnd研究中,达希纳累积MR4.5率与伊马替尼相比的结果是( )。
A. 达希纳持续优于伊马替尼
B. 伊马替尼优于达希纳
C. 结果无差别
D. 以上均不正确
【多选题】
ENESTnd研究中,达希纳体现了良好的耐受性,48个月时达希纳300mg BID组患者的实际用药剂量达预期剂量的( )。
A. 0.8
B. 0.85
C. 0.9
D. 0.99
【多选题】
ENESTnd研究中,达希纳一线治疗6年累积达到MR4.5的患者比例为
A. 0.49
B. 0.52
C. 0.56
D. 0.58
【多选题】
ENESTnd研究中,达希纳与格列卫一线治疗6年累积达到MR4.5的患者比例的差值
A. 逐渐缩小
B. 逐渐增大
C. 基本不变
D. 先增大后缩小
【多选题】
ENESTnd研究中,达希纳组患者维持在慢性期的比例是( )。
A. 0.9
B. 0.85
C. 0.99
D. 0.8
【多选题】
ENESTnd研究中,达希纳组疾病进展( )伊马替尼组。
A. 低于
B. 高于
C. 等于
D. 以上均不正确
【多选题】
ENESTnd研究中,随访5年,达希纳一线治疗组疾病进展至AP/BC的患者数与伊马替尼相比,显著更少,分别为( )例和( )例。
A. 5,5
B. 6,7
C. 2,12
D. 8,9
【多选题】
ENESTnd研究中,伊马替尼治疗CML患者发生突变比达希纳治疗的患者多
A. 1.5倍
B. 2倍
C. 2.5倍
D. 3倍
【多选题】
"ENESTnd研究中,伊马替尼组MR4.5累积率不及达希纳治疗组,并且持续证实了MR4.5率比达希纳组更低的随访时间为
【多选题】
ENESTnd研究中,在发生突变的患者中,伊马替尼治疗出现治疗失败的患者数量为达希纳治疗的
A. 2倍
B. 2.5倍
C. 3倍
D. 4倍
【多选题】
ENESTnd研究中接受达希纳300 mg BID 治疗3个月时达到EMR的中度SOKAL风险患者的比例为
A. 0.89
B. 0.9
C. 0.91
D. 0.92
【多选题】
ENESTnd研究中接受达希纳治疗的患者在6年内未进展至AP/BC的比例为
A. 0.87
B. 0.61
C. 0.59
D. 0.99
【多选题】
ENESTop研究中,在符合严格的TFR尝试资格标准的患者中,停药144周后仍可保持TFR(无MMR丢失或MR4确认丢失)的患者比例为
A. 0.189
B. 0.237
C. 0.376
D. 0.484
【多选题】
ENESTop研究中MMR丢失或MR4确认丢失后重新启动后,每月监测一次,直到以前的MMR或MR4重新建立,此后监测时间为
A. 每4周一次
B. 每6周一次
C. 每12周一次
D. 每半年一次
【多选题】
ENESTswift 研究中大约三分之一的患者在因对伊马替尼或达沙替尼耐受不良而改用达希纳3个月后达到
A. 无MMR
B. MMR
C. MR4
D. MR4.5
【多选题】
ENESTxtnd研究中,一线达希纳300mg BID治疗反应欠佳或治疗失败后患者允许增加剂量至
A. 350 mg BID
B. 400 mg BID
C. 450 mg BID
D. 500 mg BID
【多选题】
ENESTxtnd研究中,一线达希纳治疗反应欠佳或治疗失败后增加剂量治疗后患者24个月内达到MMR的比例超过
A. 0.3
B. 0.4
C. 0.5
D. 0.6
【多选题】
ENRICH研究中,接受伊马替尼治疗出现低级别慢性AEs的患者换用达希纳12个月后,达到MMR的患者比例为
A. 0.69
B. 0.78
C. 0.88
D. 0.99
【多选题】
ENRICH研究中,接受伊马替尼治疗出现低级别慢性AEs的患者换用达希纳12个月后,达到MR4.5的患者比例为
A. 0.19
B. 0.23
C. 0.42
D. 0.44
【多选题】
ENRICH研究中,接受伊马替尼治疗出现低级别慢性AEs的患者换用达希纳12个月后,达到MR4的患者比例为
A. 0.54
B. 0.64
C. 0.73
D. 0.88
【多选题】
GIMEMA CML工作组数据,格列卫治疗CML-AP患者,( ) 患者回复至慢性期。删除
A. 0.7
B. 0.85
C. 0.9
D. 0.96