【填空题】
758.运送备用钢轨及工具材料至施工现场，放在道心时，距线路的钢轨净距不少于300㎜。___
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759.运送备用钢轨及工具材料至施工现场，新轨高度不得超过线路上的钢轨面25㎜。___
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760.起道捣固作业看道：起道人俯身距起道机20～30m处的标准股上往回看，以起好的地段为准，看钢轨下腭水平线的高低情况，指挥压机手起道。___
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761.起道捣固作业根据车流密度和线路状态，接头应适当抬高，不用考虑沉落量。___
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762.在坡道上起道，从上坡往下坡看时，每点都不能低，从下坡往上坡看时每点都不能高。___
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763.正线路轨距变化率不大于1/1000，其他线路不大于2/1000。___
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764.锯轨作业时，锯后钢轨长度误差不超过±5mm。___
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765.钻孔作业时，螺孔允许误差：孔径±3mm，位置±3mm。___
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766.钻孔作业时，钢轨孔两边应到棱，边缘不得有毛刺；倒棱倒角45°～60°，顺长0.5～1.0mm。___
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767.安装接头鱼尾板时，曲线线路接头的紧固顺序为：先紧2、5位，再1、6位，最后紧3、4位。___
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768.安装接头鱼尾板时，直线线路的接头螺栓紧固顺序为：先紧1、6位，再紧3、4位，最后拧紧2、5位。___
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769.安装接头鱼尾板时，初步紧固后，要用扭矩扳手按顺序扭紧螺帽，调校至所需的扭矩。___
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770.接头鱼尾板安装完成后的1至2个星期内，工班长应安排人员对该接头螺栓进行复紧。___
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771.更换铁垫板时，铁垫板应安放在木枕中间，位置正确平整，垫板外肩要与轨底密靠，空隙不超过6mm，滑床板与基本轨落槽，滑床板与基本轨及尖轨底部密贴。___
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772.更换铁垫板时，将更换下来的旧铁垫板整理收齐，放置在指定位置。___
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773.更换铁垫板时，施工前认真检查锤把及锤头飞边，严禁在钢轨面上直钉，防止飞钉伤人。___
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774.更换铁垫板时，拿取、安放、整正铁垫板时，严禁将手伸入轨底。___
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775.在尖轨与基本轨间松卸、安装螺栓时，其中放—木块，防止夹伤手指。___
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776.在接触网高架区段露天作业，严格遵守雨天作业的安全规定。防止触电伤害情况发生。___
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777.将轨距尺的固定端紧贴一条钢轨的工作边，另一端放置在另一股钢轨工作边上，并左右移动，直至到最小间距，此时刻度就是准确轨距值。___
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778.轨距尺垂直线路中心线架设在钢轨顶面，读取水平尺的气泡靠近末端相对应的值则为准确水平值。___
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779.线路工班人员应规定定期用钢轨磨耗测量仪检测轨道上的钢轨侧面、垂直磨耗情况。___
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780.钢轨磨耗检测方法：将磨耗测量仪紧贴钢轨行车工作边的轨腰、轨头，调校测量仪使其密贴钢轨，然后记下钢轨侧面及垂直磨耗读数。___
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781.测量道岔转辙部分的轨道不平顺时，为防止尖轨闭合，出现夹伤意外，应将转辙机转到手动位置，并放置止动块在基本轨与尖轨之间，同时应与车站保持联络畅通。___
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782."轨道巡视作业的目的为1、确保轨道及轨道支承系统的完整性；2、鉴别轨道及其邻近的障碍物和潜在危险。"___
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783.两名线路巡检员检查一指定轨段须要执行巡道的地方包括正线、车辆段、停车场。___
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784.线路巡检员上班前应按照规定穿戴好防护服装及劳保用品。___
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785.线路的终点站或区段折返站设置折返线或折返渡线。___
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786.杭州地铁设计最高运行速度为100km/h的系统。___
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787.设在两线交叉处的警冲标，应满足相邻两线设备限界的要求。___
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789.正线及配线钢轨宜采用50kg/m钢轨，车场线宜采用60kg/m钢轨。___
【填空题】
790.正线道岔钢轨类型应与相邻区间钢轨类型一致，并不得低于相邻区间钢轨的强度等级及材质要求。___
【填空题】
791.无缝线路设计应根据当地气象及地下线温度资料确定设计锁定轨温，并应对轨道结构强度、稳定性等进行计算。___
【填空题】
792.防脱护轨应设置在钢轨内侧。___
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793.排水设施应布置合理，当与桥梁、隧道、车站等排水设施衔接时，应保证排水畅通。___
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794.排水沟的横断面应按流量及用地情况确定，路基排水设施均应采取防止冲刷或渗漏的加固措施，并应确保边坡稳定。___
【填空题】
795.维修是指根据轨道变化规律和特点或者为消除施工影响，通过目视及时发现问题并生成记录报告。___
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796.在维修计划中，应根据设备条件和实际状态，结合季节特点，合理地安排维修计划和重点工作。___
【填空题】
797．线路设备状态评定时以km为单位，满分为100分，扣除缺点分后，85～100分为优良，60～85分为合格，60分以下为不合格。___
【填空题】
798.线路轨道、道岔保养质量评定，是考核线路轨道、道岔养护工作质量的基本指标，也是安排维修计划的主要依据。___
推荐试题
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
