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51、选拔任用党政领导干部,必须把___放在首位。
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52、把___作为干部工作核心理念贯穿选人用人全过程,做到公道对待干部、公平评价干部、公正使用干部。
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54、省委十届六次全会指出,要把___作为一项战略的性、基础性工程。
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55、在剧院观看演出不宜___退场,如需要退场要安排在幕间或一个节目结束后。
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56、每年的12月13日为南京大屠杀死难者___,以国家公祭的方式,祭奠在南京大屠杀中死亡的30多万同胞。
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58、太学即古代国立大学,目前保留最早的太学遗址位于河南___。
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59、中国特色社会主义文化,源自于中华民族五千多年文明历史所孕育的___,熔铸于党领导人民在革命、建设、改革中创造的革命文化和社会主义先进文化,植根于中国特色社会主义伟大实践。
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60、群众路线是党的根本工作路线,以毛泽东为主要代表的中国共产党在长期斗争中形成了___,___和从群众中来,到群众中去的群众路线。
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61、南水北调中线工程的源头是___、渠首在河南省南阳市淅川县丹阳村。
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62、在正式场合,如采取“正襟危坐”,上身与大腿、大腿与小腿、小腿与地面,应当均为___。
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63、为了增强全社会的宪法意识,弘扬宪法精神,加强宪法实施,全面推进依法治国,将每年的12月4日设立为___。
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64、河南省总面积16.7万平方公里,居全国各省区市第___位,占全国总面积的1.73%。(答案中的数字使用阿拉伯数字)
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65、历史小说作家___,原名凌解放,南阳作家群代表人物。他创作的“帝王系列”——《康熙大帝》《雍正皇帝》《乾隆皇帝》被改编成多部影视剧,为海内外读者熟知。
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66、2019年4月19日,中共中央政治局举行第十四次集体学习。中共中央总书记习近平在主持学习时强调,加强对五四运动和___的研究,激励广大青年为民族复兴不懈奋斗。
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68、2014年7月23日,中央精神文明建设指导委员会印发《关于推进诚信建设制度化的意见》,就着力推进诚信建设___、___、长效化做出了明确规定。
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69、2018年12月18日,庆祝改革开放40周年大会在北京人民大会堂隆重举行。大会表彰了100名“___”称号获得者和10名“___”获得者。
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70、在开展“诚信,让河南更出彩”主题活动中,要持续开展全员诚信主题教育,引导干部职工自觉践行《___》,培育诚信理念、规则意识、契约精神。
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71、党的十八届四中全会提出,坚持依法治国首先要坚持___。
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73、孔子提出要敬畏天命,主动担当起上天赋予自己的历史使命和责任。他的思想的核心是“___”,主张“仁者爱人”、“见利思义”、“己所不欲,勿施于人”等。
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74、在长期实践中,我们党坚持把开展严肃认真的党内政治生活作为党的建设重要任务来抓,形成了以___、理论联系实际、密切联系群众、批评和自我批评、___、严明党的纪律等为主要内容的党内政治生活基本规范。
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75、党员要做到的“四个合格”是指:___、执行纪律合格、品德合格、发挥作用合格。
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77、2019年1月3日上午10点26分,“___”探测器成功着陆在月球背面东经177.6度、南纬45.5度附近的预选着陆区,并通过“___”中继星传回了世界第一张近距离拍摄的月背影像图,揭开了古老月背的神秘面纱。
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78、毛泽东提出愚公精神的核心内容是:“___,不怕牺牲, ___,去争取胜利”。
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80、“四风问题”是指:___、___、享乐主义和奢靡之风。
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81、___是当代中国精神的集中体现,凝结着全体人民共同的价值追求。
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82、2019年1月2日,中国政府网公布《国务院关于河北___新区总体规划(2018—2035年)的批复》
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83、举旗帜,就是要高举马克思主义、中国特色社会主义的旗帜,坚持不懈用新时代中国特色社会主义思想武装全党、教育人民、推动工作,在___上下功夫,推动当代中国马克思主义、21世纪马克思主义深入人心、落地生根、
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84、中国共产党在社会主义初级阶段的基本路线是:领导和团结全国各族人民,以___为中心,坚持四项基本原则,坚持___,自力更生,艰苦创业,为把我国建设成为富强民主文明和谐美丽的社会主义现代化强国而奋斗
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85、2019年5月15日,亚洲文明对话大会在北京隆重举行,国家主席习近平在开幕式上发表发表题为《深化文明交流互鉴共建亚洲___》的主旨演讲。
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86、著名抗日民族英雄、东北抗日联军创建人和领导人___,于1905年生于河南省确山县。在他牺牲后,当残忍的日军割头剖腹,发现他的胃里尽是枯草、树皮和棉絮,竟无一粒粮食,也无不为之震惊。
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87、2019年4月24日,“一带一路”___成立大会在北京召开,这是响应中国国家主席习近平“要发挥智库作用,建设好智库联盟和合作网络”建议的重要举措,也是对中外专家关于搭建合作平台、推动“一带一路”学术交流机制化常态化共同意愿的积极回应。
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88、2019年3月30日,首个行政区域5G网络在___建成并开始试用。
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89、文明家庭创建要更加注重___、注重___、注重___,促进家庭和睦,促进亲人相亲相爱,孝老爱幼,少有所教,老有所养,使千千万万个家庭成为国家发展、民族进步、社会和谐的重要基点,成为人们梦想启航的地方。
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91、大力倡导雷锋精神,弘扬___、友爱、___、进步的志愿精神,.进一步推动学雷锋志愿服务活动持续深入发展。
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92、《___》是西汉著名史学家司马迁撰写的一部纪传体史书,是中国历史上第一部纪传体通史,被列为“二十四史”之首。
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93、2019年3月15日,十三届全国人大二次会议表决通过《中华人民共和国___》本部法律是贯彻落实党中央扩大对外开放、促进外商投资决策部署的重要举措。
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94、2018年12月18日,在庆祝改革开放40周年大会上,100名改革先锋受到隆重表彰,在这100名改革先锋中,被誉为“乡镇党委书记的榜样”的河南省卫辉市唐庄镇党委书记___入选。
【填空题】
省委十届六次全会指出,推动经济高质量发展,要坚持___工作总基调,始终把握好稳增长和调结构这个重要关系。
【填空题】
95、要把___作为群众性精神文明创建活动的中心环节,让理想信念的明灯永远在全国各族人民心中闪亮。
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96、宣传思想干部要不断增强___,眼力,___,笔力,努力打造一支政治过硬,本领高强,求实创新,能打胜仗的宣传思想工作队伍。
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【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
(2)Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
(7)Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
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The nervous system uses electrical signals to transmit information very rapidly to specific cells.
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With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
(3) As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site(s) of action.
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
【单选题】
(1)地球表层覆盖着很多圈层,其中最厚的圈层是 ___
A. 岩石圈
B. 水圈
C. 大气圈
D. 生物圈