【多选题】
有研究表明，母乳中伊马替尼的浓度是血浆浓度的一半。
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有研究推荐，晚期CML患者移植后的GVHD，可接受全身性类固醇治疗治疗。
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与竞品达沙替尼相比，达希纳非血液学不良反应交叉不耐受发生率高？
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"与竞品达沙替尼相比，达希纳精准强效抑制BCR-ABL
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在ENEST1st研究中接受达希纳治疗的患者中，超过五分之一12个月内达到 MR4.5 ，在24个月内比例几乎翻倍，约39达到MR4.5。
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在ENESTnd或DASISION研究中，5年随访时，伊马替尼二线治疗组获得MR4.5的中位时间均未达到。
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在ENESTnd研究所有风险组中，伊马替尼治疗的EMR失败率比达希纳高3-4倍。
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在ENESTnd研究中, 达希纳组实现MR4.5的中位时间 > 2年较伊马替尼快。
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在ENESTnd研究中，在伊马替尼400mg每天治疗失败后将剂量增加至600或800 mg每天不会导致超过一半的患者反应改善。
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在服药前至少4小时以及服药后至少4小时内不能进食？
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在使用达希纳以前不需要纠正低钾和低镁以及定期进行监测。
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只用IS RQ-PCR方法就可以确认是否获得了关键的分子学反应。
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治疗中止时患者获得MMR、CCyR或MCyR，100%的患者发生分子学和/或细胞遗传学复发。删除
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中国CML指南推荐，Ph+ CML-CP患者一线接受伊马替尼600 mg QD治疗。
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ENESTnd标志性分析中，3个月时获得BCR-ABL IS≤10%与60个月时更佳的OS无关
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格列卫STIM研究表明，格列卫治疗时间≥50个月的患者中断治疗后无分子学复发生存率显著更高
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有研究表明，母乳中伊马替尼的浓度是血浆浓度的一半。
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只用IS RQ－PCR方法就可以确认是否获得了关键的分子学反应。
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信息显示系统车载屏厕所显示器不正常故障处理方法之一为：___损坏，应进行更换。
A. 顺号调节器
B. 显示模块
C. GPS
D. 主控板
【单选题】
旅客列车餐车电磁灶不加热故障处理方法之一为：没有电源进入，检查电磁灶保险丝有没有熔断,检查相关___。
A. 控制开关
B. 过滤器
C. 风扇
D. 电源线路
【单选题】
旅客列车餐车DZ-4Q电热炸炉绿指示灯亮，油温不升故障处理方法之一为：电热管烧坏，更换___。
A. 过欠压保护器
B. 温控器
C. 电热管
D. 指示灯
【单选题】
旅客列车餐车DZX-9L电蒸饭箱加水指示灯亮，不能加热发生蒸汽故障处理方法之一为：电热管烧坏，更换___。
A. 电热管
B. 电磁阀
C. 启动按钮
D. 水位传感器
【单选题】
旅客列车餐车LC7-7立式冰箱显示Er2故障处理方法之一为：制冷效果不良，检查___。
A. 制冷系统是否渗漏
B. 供电线路、电压，排除供电电压过低的现象
C. 供电线路、电压及接线
D. 探头与蒸发管接触良好
【单选题】
“KAX-1客车行车安全监测诊断系统”车辆制动监测诊断子系统监测列车支管和制动管路的___,诊断制动机的制动/缓解工况，报告有无制动/缓解作用不良、自然制动、自然缓解故障。
【单选题】
“KAX-1客车行车安全监测诊断系统”车辆转向架状态监测诊断子系统在车辆一/二端的车体、转向架上安装加速度传感器。监测轮轴与一系/二系悬挂系统，并根据车体的___监测整个车辆系统的状态 。
【单选题】
TFX1型电子防滑器工作原理之一为：TFX1型防滑系统采用两种防滑判据，即减速度和___。
A. 电压差
B. 电流差
C. 速度差
D. 转速差
【单选题】
TFX1型电子防滑器防滑作用自动切换功能之一为：如果一辆车中四个防滑排风阀良好，即使只剩下一个___还在正常工作，四条轮对都能得到保护。
A. 主机
B. 速度传感器
C. 排风阀
D. 压力开关
【单选题】
康尼MS730CP50电控气动塞拉门电控系统整列车塞拉门的电控系统主要由一个___和各车箱的单车电控系统组成。
A. PLC
B. WG型网关
C. 电源箱
D. 集控箱
【单选题】
AC380V供电运用列车车体配线的绝缘测量用500V级绝缘电阻计测量，线间绝缘电阻值在相对湿度为60%以下时）≥___。
A. 0.2MΩ
B. 1MΩ
C. 2MΩ
D. 4MΩ
【单选题】
J5 型感应子发电机由机座、定子铁芯、转子、激磁绕组和电枢绕组、___、轴承及轴承盖等部分组成。
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KP-2A型控制箱由___个回路组成，即主整流回路、激磁回路、测量回路、触发器回路、限流充电回路、起激回路、过压保护回路。
【单选题】
TFX1型电子防滑器排风阀的结构：该阀的空气通路直径不小于___，完全适应于防滑器的快速控制要求。
A. 0.5mm
B. 1mm
C. 2mm
D. 3mm
【单选题】
TFX1型电子防滑器监视功能：防滑器___对各组成部分不间断地进行监视。
A. 主机
B. 速度传感器
C. 排风阀
D. 压力开关
【单选题】
我国客车车轴发电机供电方式是采用车轴驱动的发电机与蓄电池组并联向负载供电。轴驱式发电机的工作电压，当功率小于3kW时用24V，功率为3～10kW时用48V，功率在10kW以上时采用___。
A. 110V
B. 220V
C. 380V
D. 600V
【单选题】
如果上一级保护失控，加热管继续加热，加热腔将被烧干，当电热管露出水面时，加热腔内的温度进一步提高、达到规定温度值时，装在___上的温度保险器动作，切断加热回路，确保安全。
A. 冷水缺水保护器
B. 开水满水保护器
C. 磁化过滤器
D. 加热管
【单选题】
康尼MS730CP50电控气动塞拉门可用手动操作开门。开门：用专用三角钥匙按紧急解锁装置（或外操作装置）标记上箭头所指方向（顺时针）转动装置上的三角头转轴约___实现解锁后，用手拉动门扇即可实现开门。
A. 30°
B. 45°
C. 90°
D. 180°
【单选题】
康尼MS730CP50电控气动塞拉门电控气动操作开门：在有集控关门信号且有电有气时，内操作装置不能开门，操作外操作装置压下微动开关，系统将关门电磁阀电源切断，这时可以手动开门，___后门将自动关闭。
A. 3s
B. 6s
C. 10s
D. 30s
【单选题】
康尼MS730CP50电控气动塞拉门集控处在关门状态时，各车厢单门系统的内操作不能电控开门，外操作只能实现手动开门，___后自动关门。
A. 3s
B. 6s
C. 10s
D. 30s
【单选题】
“KAX-1客车行车安全监测诊断系统”列车级通信网络收发器采用双绞线收发器FTT-10A，传输介质采用双绞屏蔽线，传输速率78.5Kb/S，传输距离___。
A. 1000m
B. 2000m
C. 2700m
D. 3000m
【单选题】
欧特美电动内端拉门的电气系统之电动门门控制系统电机概述：无刷电机电机功率为___、电机驱动器和减速器为集成一体化的结构。
A. 30W
B. 40W
C. 50W
D. 57W
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【单选题】
If you don’t ___ cooking today, we can go out to eat at the new restaurant.
A. would like
B. go on with
C. feel like
D. figure out、
【单选题】
Bullying (恃强欺弱) can ___ a climate of fear and anxiety in school, and prevent students from focusing on their schoolwork.
A. keep back
B. give rise to
C. feel like
D. make use of
【单选题】
Science can now ___ many things which were thought to be mysterious by ancient people.
A. care for
B. lay out
C. account for
D. set up
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The school has ___ many after-class activity groups for the pupils to make their spare time more colorful.
A. set up
B. set off
C. set out
D. set down
【单选题】
When he was a small kid, he ___ from his peers because he could read fast and remember whatever he rea D.
A. showed off
B. worked out
C. stood out
D. straightened up
【单选题】
The fall in the number of deaths from heart disease is generally ___ improvements in diet.
A. put up with
B. attributed to
C. added to
D. replaced with
【单选题】
We can be partners for now, but ultimately you have to ___ to develop a new software for our project.
A. keep up
B. fire off
C. make sense
D. take the lead
【单选题】
Emotional Intelligence (情商) could be of practical use in many ___ such as how companies decide which job applicant to hire, how parents should raise their children, how schools should teach the students, and so on.
A. aspects
B. disciplines
C. structures
D. opportunities
【单选题】
The teacher should praise students for their correct answers and also suggest ___ possibilities.
A. unlimited
B. unique
C. alternative
D. essential
【单选题】
In some classrooms, desks are arranged in a U-shape, so the teacher can ___ easily with the students.
A. interrupt
B. interact
C. interpret
D. interview
【单选题】
Computer technology ___ individuals to educate themselves and adapt to a constantly changing job market.
A. lets
B. makes
C. enables
D. provides
【单选题】
Our hope for an enjoyable dinner was instantly ___ when the waiter dropped a salad plate on my hea D.
A. spoiled
B. restricted
C. exploded
D. vanished
【单选题】
___ the world has ever seen has occurred in the information and communications technologies.
A. Great a change
B. The great change
C. A greatest change
D. The greatest change
【单选题】
___ so many people around, it wasn’t convenient to have a long talk with him.
A. As
B. When
C. With
D. Since
【单选题】
Alice used to be terribly shy, but working abroad for a year has completely ___ her.
A. solved
B. transformed
C. characterized
D. regulated
【单选题】
Chinese Mandarin (普通话) is ___ for foreigners to learn because the changes in the tone will totally change the meaning of words.
A. difficult
B. accessible
C. competitive
D. easy
【单选题】
Take action on those things that will have the biggest ___ impact on your life with the least amount of effort.
A. portable
B. positive
C. sophisticated
D. moderate
【单选题】
The adoption of this measure will greatly reduce the ___ of greenhouse gas emissions (排放物), which may help slow global warming.
A. loan
B. decline
C. release
D. response
【单选题】
I think I have a healthy lifestyle. I eat a lot of fruit and vegetables, and I’m a ___ drinker.
A. moderate
B. heavy
C. gradual
D. delicate
【单选题】
In a way the human race needs to improve its mental and physical qualities if it is to deal with the more and more ___ world and meet new challenges.
A. typical
B. complex
C. rational
D. orderly
【单选题】
If a person simply does not care about this activity, it’s ___ impossible to get him to participate.
A. barely
B. seldom
C. hardly
D. practically
【单选题】
Sometimes, even when the mind ___ functioning, the body keeps on working normally.
A. ceases
B. arouses
C. regulates
D. specializes
【单选题】
Jeffery expressed his ___ about the health and fitness of his co-workers, but they said they didn’t want to “waste time” on an exercise bike or jogging.
A. agony
B. concern
C. addiction
D. feedback
【单选题】
Such chemicals are indeed negatively ___ those humans to whom they are expose D.
A. risking
B. detecting
C. impacting
D. overwhelming
【单选题】
We regret for selling you the faulty product, and our company has agreed to ___ you by $500.
A. match
B. reverse
C. reward
D. compensate
【单选题】
This lecture taught me how to manage my time better to include my online studies in my busy ___.
A. schedule
B. outline
C. structure
D. responsibility
【单选题】
Generally speaking, an Irish person will not accept an offer straight away; he will ___ once or twice first before accepting it.
A. receive
B. decline
C. summarize
D. polish
【单选题】
There is every possibility that many species (物种) of animals will die out because of their disappearing food ___.
A. mode
B. source
C. pattern
D. foundation
【单选题】
As a college student, you should enjoy learning and get yourself ___ in those things that interest you.
A. concerned
B. devoted
C. involved
D. pursued
【单选题】
The name of Hitler (希特勒) has always been associated with war and ___ killing in the minds of those people who lived through World War Two.
A. imaginary
B. multiple
C. indispensable
D. massive
【单选题】
He works hard every day to make more money, but he ___ his health, time with his family, and the hobbies he once love D.
A. neglects
B. reminds
C. ceases
D. Declines
【单选题】
I asked a passenger sitting beside me if our train was the Westlake Express train, and he said he ___ of it.
A. not even heard
B. had not even heard
C. even not heard
D. ever had not heard
【单选题】
Whatever you say in the paper has to ___ your own thinking; hence simply repeating the professor’s opinions or whatever is in the readings will not get you very far.
A. ignore
B. arouse
C. reflect
D. release
【单选题】
We are sorry to know that they did not succeed ___ the project for lack of necessary funds.
A. to fulfill
B. to have fulfilled
C. in fulfilling
D. with fulfilling
【单选题】
It is surprising that fewer students were prepared to undertake the ___ to hand in written work on a regular basis, or to study over long periods.
A. engagement
B. commitment
C. authority
D. aspiration
【单选题】
Emily felt hurt and ___ by a close friend who had borrowed a considerable sum of money to pay for a house and then took it as a gift, never thinking of giving back the money.
A. conflicted
B. curbed
C. swollen
D. betrayed
【单选题】
In 1988 the old system was ___ in the country and a new system was introduced to take effect in 1990.
A. transmitted
B. abolished
C. assumed
D. compensated
【单选题】
We should not ___ ourselves to the classroom. We should go out of the classroom, see the world and talk to others as much as we can.
A. entertain
B. confine
C. assign
D. involve
【单选题】
I have always been grateful ___ Fred __the generous and helpful information when I was at the crossroads.
A. to … for
B. to … with
C. for … with
D. for … to
【单选题】
I think we both need to ___ the past, be happy about what we had for a time, learn from our experiences, and move on from there.
A. let go of
B. give authority to
C. make sense of
D. keep up with
