【判断题】
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【判断题】
树立党日制度的法规意识，党日可以用于其他活动内容。
【判断题】
党员要积极参加党日活动，因公出差或其他特殊原因不能参加要事先请假，事后要主动了解情况，及时补课。
【判断题】
党员如果没有正当理由，不参加党日活动，应根据情节轻重给予批评教育和警告处分。
【判断题】
党支部要确定好活动日主题，不需要制定党日活动计划。
【判断题】
宣传工作的主要任务和内容是宣传党的理论、路线、方针、政策。
【判断题】
党群工作部要坚持学习党的基本理论、路线方针政策，经公司人力资源部批准后组织实施。
【判断题】
切实做好对内对外宣传工作，使公司新闻宣传工作真正起到树正气、鼓干劲、解迷惘、促发展、塑形象的巨大作用。
【判断题】
由基层党组织全体员工参加党员活动日，活动主题根据工作情况确定。
【判断题】
统一建立规范化、常态化的党员活动制度。
【判断题】
切实提高广大党员引领和实践科学发展的能力，建立党员活动制度，进一步搭建党员管理服务平台。
【单选题】
DIN复制之初，参与从超螺旋结构解开双股链的酶或因子是___
A. 解链酶
B. 拓扑异构酶I
C. DNA结合蛋白
D. 引发前体
E. 拓扑异构鹏Ⅱ
【单选题】
关于DNA复制中DNA聚合酶的说法错误的是___
A. 底物是dNTP
B. 必须有DNA模板
C. 合成方向只能是5'→3'
D. 原核生物有三种DNA聚合酶
E. 使DNA双链解开
【单选题】
下列过程中需要DNA连接酶的是___
A. DNA复制
B. RNA转录
C. DNA断裂和修饰
D. DNA的甲基化
E. DNA的乙酰化
【单选题】
在DNA复制中，链的延长上起重要作用的是___
A. DNA聚合酶I
B. RNA聚合酶Ⅲ
C. DNA聚合酶Ⅱ
D. DnaA 蛋白和DnaB蛋白
E. 以上都不是
【单选题】
下列关于DNA复制特点的叙述哪-项是错误的___
A. 有RNA参与
B. 新生A链治5'→3'方向合成
C. DNA 链的合成是不连续的
D. 复制总是定点双向进行的
E. 在一条母链上沿5'→3'方向合成，而在另条母链上则沿3'→5'方向合成
【单选题】
辨认DNA复制起始点主要依靠的酶是___
A. DNA聚合酶
B. DNA 连接酶
C. DnaA蛋白
D. 拓扑异构酶
E. 解链酵
【单选题】
反转录过程中需要的酶是___
A. DNA指导的DNA聚合酶
B. 核酸酶
C. RNA指导的RNA聚合酶
D. DNA指导的RNA聚合酶
E. RNA指导的DNA聚合酶
【单选题】
DNA合成中拓扑异构酶的功能是___
A. 解开DNA双链成为单链(单股)
B. 稳定DNA的单链结构
C. 促进引发体的生成
D. 使冈崎片段连成长链DNA
E. 解开DNA超螺旋成松弛的双螺旋结构
【单选题】
Meselson 和Stahl利用15N及14N标记大肠杆菌的实验证明的反应机制是___
A. DNA能被复制
B. DNA可转录为mRNA
C. DNA 可表达为蛋白质
D. DNA 的半保留复制
E. DNA的全保留复制
【单选题】
哺乳类动物DNA复制叙述错误的是___
A. RNA引物较小
B. 冈畸片段较小
C. DNA聚合酶δ和α参与
D. 仅有一个复制起始点
E. 片段连接时由ATP供给能量
【单选题】
下列对大肠杆菌DNA聚合酶的叙述，不正确的是___
A. DNApol I可分为大小两个片段
B. DNApolⅡ具有3'→5'的外切酶活性
C. DNApolIlI在复制链延长中起主要作用
D. DNApolⅢ由四个亚基组成
E. 以四种脱氧核苷酸作为作用物
【单选题】
关于DNA复制中连接酶的叙述错误的是___
A. 催化相邻的DNA片段以2',5'-磷酸二酯键相连
B. 连接反应需要ATP或NAD+参与
C. 催化相邻的DNA片段以3'，5'-磷酸二酯键相连
D. 参与随从链的生成
E. 参与领头链的生成
【单选题】
DNA复制时，子代DNA的合成方式是___
A. 两条链均为不连续合成
B. 两条链均为连续合成
C. 两条链均为不对称转录合成
D. 两条链均为5'→3'合成
E. 一条链5'→3'合成，另一条链3'→5'合成
【单选题】
关于反转录酶的叙述错误的是___
A. 作用物为四种dNTP
B. 催化RNA的水解反应
C. 合成方向3'→5'
D. 催化以RMA为模板进行DNA合成
E. 可形成DNA-RNA杂交体中间产物
【单选题】
DNA复制发生在细胞周期的___
A. G1期
B. G2期
C. M期
D. S期
E. 以上都不是
【单选题】
与DNA修复过程缺陷有关的疾病是___
A. 黄嘌呤尿症
B. 着色性干皮病
C. 卟啉病
D. 痛风
E. 黄疸
【单选题】
在DNA生物合成中，具有催化RNA指导的DNA聚合反应，RNA水解及DNA指导的DNA聚合反应三种功能的酶是___
A. DNA 聚合酶
B. RNA聚合酶
C. 反转录酶
D. DNA水解酶
E. 连接酶
【单选题】
DNA复制与转录过程的许多异同点中，描述错误的是___
A. 转录是只有一条DNA链作为模板，而复制时两条DNA链均可为模板链
B. 在复制和转录中合成方向都为5'→3'
C. 复制的产物通常大于转录产物
D. 两过程均衢RNA引物
E. 两过程均需聚合酶和多种蛋白因子
【单选题】
关于大肠杆菌DNA聚合酶Ⅲ说法错误的是___
A. 催化dNTP连接到DNA片段的5'羟基末端
B. 催化dNTP连接到引物链上
C. 需要四种不同的dNTP为作用物
D. 不具5'→3'外切酶活性
E. 在DNA复制链的延长中起主要作用
【单选题】
生物遗传信息传递的中心法则中不包括___
A. DNA→DNA
B. DNA→RNA
C. RNA→DNA
D. RNA→RNA
E. 蛋白质→RMA
【单选题】
生物遗传信息传递的中心法则是___
A. 以DNA为中心
B. 以RNA为中心
C. 以蛋白质为中心
D. 以复制为中心
E. 以转录为中心
【单选题】
关于DNA合成的叙述，正确的是___
A. DNA的生物合成即DNA的半保留复制
B. DNA的生物合成必须以DNA为模板
C. DNA的生物合成必须以DNA指导的DNA聚合酶催化
D. DNA的生物合成是半不连续复制
E. DNA的生物合成包括DNA的半保留复制、DNA的修复合成和反转录
【单选题】
下列关于DNA复制的叙述，错误的是___
A. 是半保留复制
B. 合成方向为5'→3'
C. 以4种dNTP为原料
D. 为半不连续合成
E. 需解链酶、DNA 聚合酶、连接酶、限制性内切酶等参与
【单选题】
关于DNA半不连续合成的叙述，错误的是___
A. 前导链是连续合成的
B. 随从链是不连续合成的
C. ,不连续合成的片段是冈崎片段
D. 随从链的合成方向为3'→5'，前导链合成方向为5'→3'
E. ,随从链的合成滞后于前导链
【单选题】
25,真核细胞中DNA复制是在哪个部位进行的___
A. 核蛋白体
B. 线粒体
C. 细胞核
D. 微粒体
E. 细胞浆
【单选题】
DNA复制的引物是___
A. 以DNA为模板合成的DNA片段
B. 以RNA为模板合成的DNA片段
C. 以DNA的一个基因为模板合成的RNA片段
D. 以复制起始处的DNA为模板合成的RNA短片段
E. 引物存在于复制完成的片段中
【单选题】
冈崎片段是___
A. DNA模板上的DNA片段
B. 引物酶仙化合成的限片段
C. 以5'→3'DMA链为机板合成的DNA片段
D. 以3'→5'DNA链为模板合成的DNA片段
E. 前导链中的DNA片段
【单选题】
关于DNA复制中的DNA聚合酶催化的反应，叙述错误的是___
A. 底物都是dNTP
B. 需要DNA模板
C. 合成方向为5'→3'
D. 需Mg2+参与
E. 需ATP供能
【单选题】
大肠杆菌DNA聚合酶___
A. 具有3'→5'核酸外切酶活性
B. 具有3'→5'聚合酶活性
C. 不需引物
D. 可催化2个游离的dNTP以3', 5'磷酸二酯键相连
E. 需4种NTP为底物
推荐试题
【单选题】
(5)Whicl of the following is a physiological process with negative feedback?___
A. blood coagulation
B. process of passing urine
C. sino-aortic baroreceptor reflex
D. process of parturition
【单选题】
(6)Which of the following is not the characteristic of regulation by hormone?___
A. diffusenin nature
B. longer in duration
C. accurate in action
D. action in overcorrection
【单选题】
7)Which of the following is not the characteristic of cells?___
A. They are bound by the plasma membrane
B. They have the ability to break down large molecules to smaller ones to Liberate energy for their activities
C. They possess a nucleus which contains genetic information in the form of deoxyribonucleicacid(DNA).
D. Living cells can not transform materials.
【单选题】
8)The breakdown of large molecules to smaller ones is called___
A. respiration
B. anabolism
C. catabolism
D. absorption
【单选题】
9) Which of the following descriptions about the characteristics of nervous regulation is wrong?___
A. It responds fast
B. It acts exactly
C. It responds slowly.D.
D. uration is short
【单选题】
10)Which of the following descriptions about the control of body function is wrong?___
A. Homeostasis is kept by feedback control.
B. Negative feedback minimizes the changes, leading to stability.
C. Positive feedback is not useful.
D. Feed-forward makes human body foresee and adapt itself to the environment promptly.
【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
