【多选题】
骨髓抑制一般是可逆的,可以通过暂时停达希纳或降低剂量来控制。
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【多选题】
关于细胞遗传学定性检测:常用于诊断和查其他异常染色体;只提供是否存在Ph+的细胞的报告,并不提供有Ph+细胞百分比;可以检测是否存在其他染色体变异。
【多选题】
缓解程度小于DMR的患者很少能成功实现停药。
【多选题】
目前在CML领域中,分子学反应缺乏统一的监测标准。
【多选题】
如果临床需要,达希纳可与造血生长因子联合使用。
【多选题】
如果心电图显示QTc> 480毫秒,则应停止服用达希纳,及时纠正低钾或低镁,并必须检查合并用药的情况。
【多选题】
为了使得不同实验室测定的结果具有可比性,需要将各个实验室的测定值根据国际标准进行标准化。
【多选题】
相对伊马替尼,达希纳更容易与ABL结构域紧密结合?
【多选题】
荧光原位杂交(FISH)可以在200个细胞中检测出一个Ph+细胞。
【多选题】
有研究表明,母乳中伊马替尼的浓度是血浆浓度的一半。
【多选题】
有研究推荐,晚期CML患者移植后的GVHD,可接受全身性类固醇治疗治疗。
【多选题】
与竞品达沙替尼相比,达希纳非血液学不良反应交叉不耐受发生率高?
【多选题】
"与竞品达沙替尼相比,达希纳精准强效抑制BCR-ABL
【多选题】
在ENEST1st研究中接受达希纳治疗的患者中,超过五分之一12个月内达到 MR4.5 ,在24个月内比例几乎翻倍,约39达到MR4.5。
【多选题】
在ENESTnd或DASISION研究中,5年随访时,伊马替尼二线治疗组获得MR4.5的中位时间均未达到。
【多选题】
在ENESTnd研究所有风险组中,伊马替尼治疗的EMR失败率比达希纳高3-4倍。
【多选题】
在ENESTnd研究中, 达希纳组实现MR4.5的中位时间 > 2年较伊马替尼快。
【多选题】
在ENESTnd研究中,在伊马替尼400mg每天治疗失败后将剂量增加至600或800 mg每天不会导致超过一半的患者反应改善。
【多选题】
在服药前至少4小时以及服药后至少4小时内不能进食?
【多选题】
在使用达希纳以前不需要纠正低钾和低镁以及定期进行监测。
【多选题】
只用IS RQ-PCR方法就可以确认是否获得了关键的分子学反应。
【多选题】
治疗中止时患者获得MMR、CCyR或MCyR,100%的患者发生分子学和/或细胞遗传学复发。删除
【多选题】
中国CML指南推荐,Ph+ CML-CP患者一线接受伊马替尼600 mg QD治疗。
【多选题】
ENESTnd标志性分析中,3个月时获得BCR-ABL IS≤10%与60个月时更佳的OS无关
【多选题】
格列卫STIM研究表明,格列卫治疗时间≥50个月的患者中断治疗后无分子学复发生存率显著更高
【多选题】
有研究表明,母乳中伊马替尼的浓度是血浆浓度的一半。
【多选题】
只用IS RQ-PCR方法就可以确认是否获得了关键的分子学反应。
【单选题】
信息显示系统车载屏厕所显示器不正常故障处理方法之一为:___损坏,应进行更换。
A. 顺号调节器
B. 显示模块
C. GPS
D. 主控板
【单选题】
旅客列车餐车电磁灶不加热故障处理方法之一为:没有电源进入,检查电磁灶保险丝有没有熔断,检查相关___。
A. 控制开关
B. 过滤器
C. 风扇
D. 电源线路
【单选题】
旅客列车餐车DZ-4Q电热炸炉绿指示灯亮,油温不升故障处理方法之一为:电热管烧坏,更换___。
A. 过欠压保护器
B. 温控器
C. 电热管
D. 指示灯
【单选题】
旅客列车餐车DZX-9L电蒸饭箱加水指示灯亮,不能加热发生蒸汽故障处理方法之一为:电热管烧坏,更换___。
A. 电热管
B. 电磁阀
C. 启动按钮
D. 水位传感器
【单选题】
旅客列车餐车LC7-7立式冰箱显示Er2故障处理方法之一为:制冷效果不良,检查___。
A. 制冷系统是否渗漏
B. 供电线路、电压,排除供电电压过低的现象
C. 供电线路、电压及接线
D. 探头与蒸发管接触良好
【单选题】
“KAX-1客车行车安全监测诊断系统”车辆制动监测诊断子系统监测列车支管和制动管路的___,诊断制动机的制动/缓解工况,报告有无制动/缓解作用不良、自然制动、自然缓解故障。
【单选题】
“KAX-1客车行车安全监测诊断系统”车辆转向架状态监测诊断子系统在车辆一/二端的车体、转向架上安装加速度传感器。监测轮轴与一系/二系悬挂系统,并根据车体的___监测整个车辆系统的状态 。
【单选题】
TFX1型电子防滑器工作原理之一为:TFX1型防滑系统采用两种防滑判据,即减速度和___。
A. 电压差
B. 电流差
C. 速度差
D. 转速差
【单选题】
TFX1型电子防滑器防滑作用自动切换功能之一为:如果一辆车中四个防滑排风阀良好,即使只剩下一个___还在正常工作,四条轮对都能得到保护。
A. 主机
B. 速度传感器
C. 排风阀
D. 压力开关
【单选题】
康尼MS730CP50电控气动塞拉门电控系统整列车塞拉门的电控系统主要由一个___和各车箱的单车电控系统组成。
A. PLC
B. WG型网关
C. 电源箱
D. 集控箱
【单选题】
AC380V供电运用列车车体配线的绝缘测量用500V级绝缘电阻计测量,线间绝缘电阻值在相对湿度为60%以下时)≥___。
A. 0.2MΩ
B. 1MΩ
C. 2MΩ
D. 4MΩ
【单选题】
J5 型感应子发电机由机座、定子铁芯、转子、激磁绕组和电枢绕组、___、轴承及轴承盖等部分组成。
推荐试题
【单选题】
- I hear you got through your exam. Congratulations!____
A. No. I didn't do well enough.
B. Who told you that?
C. Thanks.
D. Yes, I got a good mark.
【单选题】
- Don't forget to come to my party this evening!___
A. I can't.
B. I won't.
C. I don't.
D. I will.
【单选题】
- Jim, please don't put your head out of the window on the bus. It's dangerous!___
A. Good idea.
B. Sorry, I won't do it again.
C. It doesn't matter.
D. It's good.
【单选题】
-How about going fishing?___, I have no patience for that.
A. Excuse me
B. Sorry
C. Pardon
D. Apologize
【单选题】
- Thanks for the lovely and delicious food______.
A. No thanks
B. Never mind
C. All right
D. My pleasure
【单选题】
- Haven't seen you for ages. Let's have a get-together next week._____
A. Great idea.
B. Welcome!
C. Yes, of course.
D. No, thanks.
【单选题】
- Do you mind if I switch off the radio? ______. Go ahead.
A. Never mind
B. No way
C. No, not at all
D. No, you'd better not
【单选题】
- Could I use your bike for a moment? ___
A. It's well.
B. It doesn't matter.
C. By all means.
D. I have no idea.
【单选题】
-How do you like the story?_______.
A. I'd like to read it
B. I like it very much
C. fine, thank you
D. It's very interesting
【单选题】
- I'll sorry to trouble you.______.
A. Don't say so
B. OK
C. It doesn't matter
D. That's fight
【单选题】
- We ordered 20 boxes of your products, but we have only got 19. - ____
A. You do not have to.
B. It does not matter.
C. We will send another tomorrow.
D. Nothing serious.
【单选题】
--Will you please give the note to him? _________.
A. Certainly, I'll give it to him
B. No, please not
C. Sorry, I don't
D. Yes, please do
【单选题】
- Thank you ever so much for your lovely gift____
A. Never mind
B. I'm glad you like it.
C. Please don't say so.
D. No, It's not so good.
【单选题】
- I'd like to invite you to dinner this Saturday, Mr. Smith.____
A. Oh, no. let's not.
B. I'd rather stay at home.
C. I'm sorry, but I have other plans.
D. Oh, no. That'll be too much trouble.
【单选题】
- Could you please open the window?____
A. I can't.
B. Go ahead.
C. Sure.
D. It's really very kind.
【单选题】
- Do you think I can borrow your bike for a few hours?____
A. I'm afraid you can.
B. I'm sorry, but I really need it this afternoon.
C. Yes, I don't think so.
D. I'll think about it later.
【单选题】
- Thank you very much for the dictionary you sent me.____
A. No thanks.
B. I'm glad you like it.
C. Please don't say so.
D. No, it's not so good.
【单选题】
- How do you like the movie we saw yesterday?____
A. You are welcome.
B. How about you?
C. I've never seen a better movie than it.
D. It is very expensive.
【单选题】
- What do you think of your new teacher____
A. He came to teach us last week.
B. He teaches us English.
C. He has two children.
D. He is very nice.
【单选题】
- Are you going to have a holiday?____
A. Not until next week.
B. Three weeks ago.
C. To Beijing.
D. I'm pleased to hear that.
【单选题】
- You seem to be lost. Need help? ____
A. Yes, would you please help me with the bag?
B. Help me find my key, please.
C. Yes, with pleasure.
D. I'm looking for Zhongshan Road.
【单选题】
- Can you help me clear up the mess____
A. Yes, it doesn't matter.
B. No, that's OK.
C. Yes, help yourself.
D. No problem.
【单选题】
- Does No.20 bus stop at our school?____
A. I go to school by bus.
B. I'm afraid not.
C. You are welcome.
D. I'll not take No.20 bus.
【单选题】
- Can I help you? ____
A. Sorry, I don't need your help.
B. What help can you give us?
C. I'd like to try on these shoes, please.
D. Thanks. You are welcome.
【单选题】
- Sorry to have kept you waiting. ____
A. That's OK.
B. What are you doing?
C. What's wrong with you?
D. Where have you been?
【单选题】
- What is she?____
A. She is a typist.
B. She is talking to her friend.
C. She is having a holiday.
D. She is my sister.
【单选题】
- That's a beautiful cat. I wonder who it belongs to.____
A. It belongs to the
B. rowns. B.The cat is my favourite too.
C. Mind your own business.
D. I can't say anything more.
【单选题】
- Excuse me, could you tell me the time____
A. You'd better buy a watch.
B. It's three thirty by my watch.
C. Can you see the clock?
D. It's late I think.
【单选题】
- What do you think of the movie we saw last night?____
A. The actress is bad.
B. Terrific!
C. The theatre is bad.
D. Nobody was there.
【单选题】
___ No, thanks. I'm just looking around. I'll let you know if I want anything.
A. Could you help me?
B. What will you buy?
C. Can I help you?
D. Do you like to look around?
【单选题】
- Hello, Peter. What do you do?____
A. I am fine.
B. I am not sick.
C. I am a student from Bonn University.
D. I came from Bonn University.
【单选题】
-Excuse me; can I have a seat here?___
A. Be hurry.
B. Come on.
C. Yes, please.
D. Do you mind?
【单选题】
- Shall we sit up here on the grass or down there near the water?___
A. I'd rather stay here if you don't mind.
B. Sorry, I don't like neither.
C. Certainly, why not?
D. Yes, we like these two places.
【单选题】
- What do you do on Sunday?___
A. I 'm a teacher.
B. I play football.
C. You are a student.
D. They clean rooms.
【单选题】
- Our class won the girls' relay race in our school's sports meeting.___
A. That's right.
B. Thanks a lot.
C. Congratulations!
D. It's a pleasure.
【单选题】
- Hi, is Mary there, please?___
A. Hold on. I'll get her.
B. No, she isn't here.
C. Yes, she lives here.
D. Yes, what do you want?
【单选题】
- I am afraid I can't return the book to you before Friday. ___
A. Don't be afraid
B. Be careful
C. Not at all
D. Take your time
【单选题】
- I really don't know how to thank you enough. ___.
A. No problem
B. Think nothing of it
C. Not at all
D. It doesn't matter
【单选题】
- Must I be home before seven? ___.
A. No, you needn't
B. No, you mustn't
C. Yes, you will
D. No, you won't
【单选题】
-I'm sorry to hear that you failed in the exam______.
A. Not at all
B. Oh, thank you.That's very kind of you
C. You are welcome
D. Yes, I'm really sorry