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【单选题】
胞内受体化学性质为___
A. DNA结合蛋白
B. G蛋白
C. 糖蛋白
D. 脂蛋白
E. 糖脂
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答案
A
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【单选题】
下列哪种受体是催化型受体___
A. 胰岛素
B. 生长激素受体
C. 干扰素受体
D. 甲状腺素受体
E. 活性维生素D3受体
【单选题】
IP3相应受体结合后,可使胞浆内哪种离子浓度升高___
A. K+
B. Na+
C. HCO3-
D. Ca2+
E. Mg2+
【单选题】
心钠素通过下列哪种信息传导途径发挥调节作用___
A. cAMP‐蛋白激酶途径
B. cGMP‐蛋白激酶途径
C. Ca2+‐CaM激酶途径
D. 受体型TPK‐Ras‐MAPK途径
E. JAKs‐STAT途径
【单选题】
在细胞内传递激素信息的小分子物质称为___
A. 递质
B. 载体
C. 第一信使
D. 第二信使
E. 第三信使
【单选题】
影响离子通道开关的配体主要是___
A. 神经递质
B. 类固醇激素
C. 生长因子
D. 无机离子
E. 甲状腺素
【单选题】
cGMP能激活___
A. 磷脂酶C
B. 蛋白激酶A
C. 蛋白激酶G
D. 酪氨酸蛋白激酶
E. 蛋白激酶C
【单选题】
cAMP能别构激活___
A. 磷脂酶A
B. 蛋白激酶A
C. 蛋白激酶C
D. 蛋白激酶G
E. 酪氨酸蛋白激酶
【单选题】
下列哪种物质不是细胞间信息物质___
A. 一氧化氮
B. 葡萄糖
C. 甘氨酸
D. 前列腺素
E. 乙酰胆碱
【单选题】
激活的G蛋白直接影响下列哪种酶___
A. 蛋白激酶A
B. 蛋白激酶C
C. 蛋白激酶G
D. 磷脂酶A
E. 磷脂酶C
【单选题】
G蛋白是指___
A. 蛋白激酶A
B. 鸟苷酸环化酶
C. 蛋白激酶G
D. Grb-2结合蛋白
E. 鸟苷酸结合蛋白
【单选题】
下列哪项是小G蛋白___
A. G蛋白的亚基
B. Grb-2结合蛋白
C. 蛋白激酶G
D. Ras蛋白
E. Raf蛋白
【单选题】
下列有关细胞内信息物质的叙述哪项是错误的___
A. 细胞内信息物质的组成多样化
B. 无机离子也是一种细胞内信息物质
C. 细胞内信息物质绝大部分通过酶促级联反应传递信号
D. 信号蛋白分子多为癌基因产物
E. 细胞内受体是激素作用的第二信使
【单选题】
在信息传递过程中产生第二信使的激素是___
A. 糖皮激素
B. 雌二醇
C. 5β-氢睾酮
D. 醛固酮
E. 促肾上腺皮质激素
【单选题】
在信息传递过程中不产生第二信使的物质是___
A. 肾上腺素
B. 胰岛素
C. 甲状腺素
D. 促肾上腺皮质激素
E. 促性腺激素
【单选题】
既能抑制腺苷酸环化酶,又能激活磷酸二酯酶的激素是___
A. 胰高血糖素
B. 肾上腺素
C. 促肾上腺皮质激素
D. 胰岛素
E. 经上都不是
【单选题】
以IP3和DAG为第二信使的双信号途径是___
A. cAMP-蛋白激酶途径
B. Ca2+‐磷脂依赖性蛋白激酶途径
C. cGMP‐蛋白激酶途径
D. 酪氨酸蛋白激活酶途径
E. 以上都不是
【单选题】
下列哪种受体与G蛋白偶联___
A. 环状受体
B. 蛇型受体
C. 催化性受体
D. 细胞核内受体
E. 细胞浆内受体
【单选题】
目前认为下列哪种蛋白激酶不直接被胞内第二信使调节___
A. PKA
B. PKC
C. PKG
D. TPK
E. Ca2+‐CaM激酶
【单选题】
其磷酸化能被激活的PKA所催化的氨基酸主要是___
A. 酪氨酸
B. 甘氨酸
C. 酪氨酸/甘氨酸
D. 甘氨酸/丝氨酸
E. 苏氨酸/丝氨酸
【单选题】
依赖Ca2+蛋白激酶是___
A. PKA
B. PKC
C. PKG
D. 受体型TPK
E. 非受体型 TPK
【单选题】
肾上腺素与膜上β受体结合,激活G蛋白后___
A. 激活鸟苷酸环化酶
B. 抑制鸟苷酸环化酶
C. 激活腺苷酸环化酶
D. 抑制腺苷酸环化酶
E. 激活磷脂酶C
【单选题】
下列哪组氨基酸容易发生磷酸化与脱磷酸___
A. Gly、Ser、Val
B. Thr、 Ser、 Tyr
C. Ala、Ile、Leu
D. Phe、Thr、Val
E. Tyr、Val、Gly
【单选题】
矩型双曲线反映了受体‐配体结合的哪一种特性___
A. 高度专一性
B. 高度亲和力
C. 可饱和性
D. 可逆性
E. 特定的作用模式
【单选题】
作为G蛋白的一种特点,其α亚基具有下列哪种酶的活性___
A. GTP酶
B. ATP酶
C. TTP酶
D. CTP酶
E. UTP酶
【单选题】
与G蛋白活化密切相关的核苷酸是___
A. ATP
B. CTP
C. GTP
D. TTP
E. UTP
【单选题】
胰岛素受体可具下列哪种酶活性___
A. 蛋白激酶A
B. 蛋白激酶C
C. 蛋白激酶G
D. 酪氨酸蛋白激酶
E. Ca2+‐CaM激酶
【单选题】
直接激活蛋白激酶C的是___
A. cAMP
B. cGMP
C. IP3
D. PIP2
E. DAG
【单选题】
蛋白激酶的作用是使蛋白质或酶___
A. 脱磷酸
B. 磷酸化
C. 水解
D. 合成
E. 激活
【多选题】
下列氨基酸中属于人类必需氨基酸的有___
A. 苯丙氨酸
B. 酪氨酸
C. 丝氨酸
D. 苏氨酸
【多选题】
一碳单位是合成下列是哪些物质所需要的原料?___
A. 腺嘌呤核苷酸
B. 胆固醇
C. 胸腺嘧啶核苷酸
D. 血红素
【多选题】
半胱氨酸代谢能生成具有重要生理功能的物质是___
A. 5-羟色胺
B. r氨基丁酸
C. 牛磺酸
D. 谷胱甘肽
【多选题】
α酮酸在体内的代谢途径有___
A. 生成相应的非必需氨基酸
B. 转变成糖和脂肪
C. 氧化生成CO2和水
D. 合成必需氨基酸
【多选题】
经转氨基作用能直接转变成常见氨基酸的α酮酸的有___
A. 草酰乙酸
B. 丙酮酸
C. α酮戊二酸
D. α酮丁酸
【多选题】
谷氨酰胺是___
A. 氨的解毒产物
B. 氨的储存形式
C. 氨的转运形式
D. 必需氨基酸
【多选题】
甘氨酸参与___
A. 血红素合成
B. 谷胱甘肽合成
C. 嘌呤核苷酸合成
D. 肌酸合成
【多选题】
下列可作为体内氨来源的有___
A. 氨基酸脱氨基作用
B. 消化道氨的吸收
C. 肾分泌的氨
D. 嘌呤、嘧啶核苷酸分解产生的氨
【多选题】
组织之间氨转运的主要形式有___
A. NH4CI
B. 丙氨酸
C. 尿素
D. 谷氨酰胺
【多选题】
一碳单位的主要形式有___
A. -CH=NH
B. -CHO
C. =CH2
D. -CH3
【多选题】
与鸟氨酸循环生成尿素直接有关的氨基酸有___
A. 鸟氨酸、瓜氨酸、精氨酸
B. 天冬氨酸
C. 谷氨酰胺
D. N-乙酰谷氨酸
【多选题】
由氨基酸参与生成的神经递质和激素有___
A. 去甲肾上腺素
B. 5-羟色胺
C. r氨基丁酸
D. 甲状腺素
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