【判断题】
生产经营单位的主要负责人依法履行安全生产工作职责，对安全生产工作部分负责，其他负责人对职责范围内的安全生产工作负责 （）
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【判断题】
安全生产监督管理部门是指县级以上人民政府负责安全生产监督管理职责的部门（）
【判断题】
《山东省安全生产条例》规定的行政处罚，是由安全生产监督管理部门和其他负有安全生产监督管理职责的部门按照职责分工决定（）
【判断题】
《安全生产法》不仅适用于生产经营单位，同时也适用于国家安全和社会治安方面的管理（）
【判断题】
《安全生产法》规定，在中华人民共和国领域内从事生产经营活动的单位的安全生产，适用本法这里所指的生产经营单位包括国有企业事业单位、集体所有制企业事业单位、合伙企业、个人独资企业，但不包括中外合资经营企业、中外合作经营企业、外资企业（）
【判断题】
《安全生产法》关于从业人员的安全生产义务主要有四项：即遵章守规，服从管理佩戴和使用劳动防护用品接受培训，掌握安全生产技能发现事故隐患及时报告（）
【判断题】
《安全生产法》规定，从业人员未经批准不可以了解其作业场所和工作岗位存在的危险因素、防范措施及事故应急措施（）
【判断题】
《安全生产法》规定，生产经营单位对安全生产监督检查人员的安全检查，应当予以配合，不得拒绝、阻挠（）
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《安全生产法》规定的行政处罚，由县级以上人民政府决定（）
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《安全生产法》规定的生产安全事故类型的划分标准由国家安全监督管理总局规定（）
【判断题】
《安全生产法》适用于中华人民共和国领域内从事生产经营活动的单位，因此，自然适用于香港和澳门两个特别行政区（）
【判断题】
安全生产监督管理部门和其他负有安全生产监督管理职责的部门对企业执行有关安全生产的法律、法规和国家标准或者行业标准的情况进行监督检查时，生产经营单位可以以技术保密、业务保密等理由拒绝检查（）
【判断题】
安全生产监督管理部门应当加强对建设单位验收活动和验收结果的监督考核（）
【判断题】
安全生产责任制是一项最基本的安全生产制度，是其他各项安全规章制度得以切实实施的基本保证（）
【判断题】
把作业场所和工作岗位存在的危险因素如实告知从业人员，会有负面影响，引起恐慌，增加思想负担，不利于安全生产（）
【判断题】
从业人员超过一百人的生产经营单位，应当设置安全生产管理机构或者配备专职安全生产管理人员（）
【判断题】
从业人员发现直接危及人身安全的紧急情况时，有权停止作业或者在采取可能的应急措施后撤离作业场所（）
【判断题】
从业人员享有批评、检举控告权和拒绝违章指挥、强令冒险作业的权利生产经营单位不得因从业人员行使上述权利而对其进行打击报复，如：降低工资、降低福利待遇和解除劳动合同等（）
【判断题】
从业人员有权对本单位安全生产工作中存在的问题提出批评、检举、控告（）
【判断题】
党和国家的安全生产方针政策、法律法规，可以通过各项安全生产规章制度和宣传教育等形式具体落实到基层，落实到每个职工（）
【判断题】
根据《中华人民共和国安全生产法》对负有责任的生产经营单位除要求其依法承担相应的赔偿等责任外，由安全生产监督管理部门进行罚款，发生生产安全事故，为较大事故的，处以五十万元以上一百万元以下的罚款（）
【判断题】
根据《中华人民共和国安全生产法》对负有责任的生产经营单位除要求其依法承担相应的赔偿等责任外，由安全生产监督管理部门进行罚款，发生生产安全事故，为一般事故的，处以十万元以上二十万元以下的罚款（）
【判断题】
负有安全生产监督管理职责的部门对检查中发现的事故隐患，应当责令立即排除（）
【判断题】
工会不能对建设项目的安全设施和主体工程同时设计、同时施工、同时投入生产和使用进行监督（）
【判断题】
工会有权依法参加事故调查，向有关部门提出处理意见，但并不能要求追究有关人员的责任（）
【判断题】
国家对严重危及生产安全的工艺、设备实行更换维修制度（）
【判断题】
国家对在改善安全生产条件、防止生产安全事故、参加抢险救护等方面取得显著成绩的单位给予奖励个人给予鼓励（）
【判断题】
国家鼓励和支持安全生产科学技术和安全生产先进技术的推广应用，提高安全生产水平（）
【判断题】
国务院安全生产监督管理部门和其他负有安全生产监督管理职责的部门应当根据各自的职责分工，制定相关行业、领域重大事故隐患的判定标准（）
【判断题】
监督检查不得影响被检查单位正常的生产经营活动（）
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矿山建设项目和用于生产、储存、装卸危险物品的建设项目，应当分别按照国家有关规定进行安全生产条件论证和安全评价（）
【判断题】
劳动防护用品不同于一般的商品，直接涉及到劳动者的生命安全和身体健康，故要求其必须符合国家标准或者行业标准（）
【判断题】
劳务派遣单位不用对被派遣劳动者进行安全生产教育和培训，而由生产经营单位培训即可（）
【判断题】
目前国家不强制要求所有生产经营单位投保安全生产责任保险（）
【判断题】
企业的安全生产管理人员可以直接任免，不用告知主管的负有安全生产监督管理职责的部门（）
【判断题】
企业的安全生产责任制应当明确各岗位的责任人员、责任范围和考核标准等内容（）
【判断题】
企业的从业人员没有经过安全教育培训，不了解规章制度，因而发生重大伤亡事故的，行为人不应负法律责任，应由发生事故的企业负有直接责任的负责人负法律责任（）
【判断题】
企业的主要负责人未履行《安全生产法》规定的安全生产管理职责，导致重大、特别重大生产安全事故的，5年内不得再担任本行业生产经营单位的主要负责人（）
【判断题】
企业接收中等职业学校、高校学生实习的，学校应当协助本单位对实习学生进行安全生产教育和培训（）
【判断题】
企业特种作业人员的范围由国务院安全生产监督管理部门会同国务院有关部门确定（）
推荐试题
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
